PTEN c.566G>A ;(p.R189K)

Variant ID: 10-89711948-G-A

NM_000314.4(PTEN):c.566G>A;(p.R189K)

This variant was identified in 4 publications

View GRCh38 version.




Publications:


Impact of p85α Alterations in Cancer.

Biomolecules
Marshall, Jeremy D S JDS; Whitecross, Dielle E DE; Mellor, Paul P; Anderson, Deborah H DH
Publication Date: 2019-01-15

Variant appearance in text: PTEN: R189K
PubMed Link: 30650664
Variant Present in the following documents:
  • Main text
View BVdb publication page



Pilot investigation of the mutation profile of PIK3CA/PTEN genes (PI3K pathway) in grade 3 endometrial cancer.

Oncology Reports
Malentacchi, Francesca F; Turrini, Irene I; Sorbi, Flavia F; Projetto, Elisabetta E; Castiglione, Francesca F; Fambrini, Massimiliano M; Petraglia, Felice F; Pillozzi, Serena S; Noci, Ivo I
Publication Date: 2019-03

Variant appearance in text: PTEN: 566G>A; R189K
PubMed Link: 30569174
Variant Present in the following documents:
  • Main text
  • or-41-03-1560.pdf
View BVdb publication page



Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Publication Date: 2018

Variant appearance in text: PTEN: R189K
PubMed Link: 29698444
Variant Present in the following documents:
  • pone.0196434.s001.xlsx, sheet 3
  • pone.0196434.s001.xlsx, sheet 2
View BVdb publication page



Mutational heterogeneity in non-serous ovarian cancers.

Scientific Reports
Teer, Jamie K JK; Yoder, Sean S; Gjyshi, Anxhela A; Nicosia, Santo V SV; Zhang, Chaomei C; Monteiro, Alvaro N A ANA
Publication Date: 2017-08-29

Variant appearance in text: PTEN: R189K
PubMed Link: 28852190
Variant Present in the following documents:
  • 41598_2017_10432_MOESM2_ESM.xlsx, sheet 5
View BVdb publication page