PTEN c.582G>C ;(p.L194F)

Variant ID: 10-89711964-G-C

NM_000314.4(PTEN):c.582G>C;(p.L194F)

This variant was identified in 4 publications

View GRCh38 version.




Publications:


Targeting the Ezrin Adaptor Protein Sensitizes Metastatic Breast Cancer Cells to Chemotherapy and Reduces Neoadjuvant Therapy-induced Metastasis.

Cancer Research Communications
Hoskin, Victoria V; Ghaffari, Abdi A; Laight, Brian J BJ; SenGupta, Sandip S; Madarnas, Yolanda Y; Nicol, Christopher J B CJB; Elliott, Bruce E BE; Varma, Sonal S; Greer, Peter A PA
Publication Date: 2022-06

Variant appearance in text: PTEN: L194F
PubMed Link: 36923551
Variant Present in the following documents:
  • crc-21-0117-s01.pdf
View BVdb publication page



Identification of potential new treatment response markers and therapeutic targets using a Gaussian process-based method in lapatinib insensitive breast cancer models.

Plos One
Santra, Tapesh T; Roche, Sandra S; Conlon, Neil N; O'Donovan, Norma N; Crown, John J; O'Connor, Robert R; Kolch, Walter W
Publication Date: 2017

Variant appearance in text: PTEN: L194F
PubMed Link: 28481952
Variant Present in the following documents:
  • Main text
  • pone.0177058.pdf
View BVdb publication page



Genome-wide effects of MELK-inhibitor in triple-negative breast cancer cells indicate context-dependent response with p53 as a key determinant.

Plos One
Simon, Marisa M; Mesmar, Fahmi F; Helguero, Luisa L; Williams, Cecilia C
Publication Date: 2017

Variant appearance in text: PTEN: L194F
PubMed Link: 28235006
Variant Present in the following documents:
  • Main text
  • pone.0172832.pdf
View BVdb publication page