PTEN c.710A>G ;(p.K237R)

Variant ID: 10-89717685-A-G

NM_000314.4(PTEN):c.710A>G;(p.K237R)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


FBXO22 degrades nuclear PTEN to promote tumorigenesis.

Nature Communications
Ge, Meng-Kai MK; Zhang, Na N; Xia, Li L; Zhang, Cheng C; Dong, Shuang-Shu SS; Li, Zhan-Ming ZM; Ji, Yan Y; Zheng, Min-Hua MH; Sun, Jing J; Chen, Guo-Qiang GQ; Shen, Shao-Ming SM
Publication Date: 2020-04-06

Variant appearance in text: PTEN: K237R
PubMed Link: 32249768
Variant Present in the following documents:
  • 41467_2020_Article_15578.pdf
View BVdb publication page



Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Publication Date: 2018

Variant appearance in text: PTEN: K237R
PubMed Link: 29698444
Variant Present in the following documents:
  • pone.0196434.s001.xlsx, sheet 3
  • pone.0196434.s001.xlsx, sheet 1
  • pone.0196434.s001.xlsx, sheet 2
View BVdb publication page



Transcriptional regulation of hepatic lipogenesis.

Nature Reviews. Molecular Cell Biology
Wang, Yuhui Y; Viscarra, Jose J; Kim, Sun-Joong SJ; Sul, Hei Sook HS
Publication Date: 2015-11

Variant appearance in text: PTEN: K237R
PubMed Link: 26490400
Variant Present in the following documents:
  • Main text
View BVdb publication page