PTEN c.727T>C ;(p.F243L)

Variant ID: 10-89717702-T-C

NM_000314.4(PTEN):c.727T>C;(p.F243L)

This variant was identified in 7 publications

View GRCh38 version.




Publications:


A Review of Margetuximab-Based Therapies in Patients with HER2-Positive Metastatic Breast Cancer.

Cancers
Alasmari, Moudi M MM
Publication Date: 2022-12-21

Variant appearance in text: PTEN: F243L
PubMed Link: 36612034
Variant Present in the following documents:
  • Main text
  • cancers-15-00038.pdf
View BVdb publication page



Comprehensive germline and somatic genomic profiles of Chinese patients with biliary tract cancer.

Frontiers In Oncology
Yu, Haipeng H; Xu, Yan Y; Gao, Wei W; Li, Mei M; He, Ji'an J; Deng, Xiaoqian X; Xing, Wenge W
Publication Date: 2022

Variant appearance in text: PTEN: F243L
PubMed Link: 36072793
Variant Present in the following documents:
  • Table_3.xlsx, sheet 1
View BVdb publication page



Relevance of Fc Gamma Receptor Polymorphisms in Cancer Therapy With Monoclonal Antibodies.

Frontiers In Oncology
Mata-Molanes, Juan J JJ; Rebollo-Liceaga, Joseba J; Martínez-Navarro, Elena Mª EM; Manzano, Ramón González RG; Brugarolas, Antonio A; Juan, Manel M; Sureda, Manuel M
Publication Date: 2022

Variant appearance in text: PTEN: F243L
PubMed Link: 35814459
Variant Present in the following documents:
  • Main text
  • fonc-12-926289.pdf
View BVdb publication page



The Right Partner in Crime: Unlocking the Potential of the Anti-EGFR Antibody Cetuximab via Combination With Natural Killer Cell Chartering Immunotherapeutic Strategies.

Frontiers In Immunology
Baysal, Hasan H; De Pauw, Ines I; Zaryouh, Hannah H; Peeters, Marc M; Vermorken, Jan Baptist JB; Lardon, Filip F; De Waele, Jorrit J; Wouters, An A
Publication Date: 2021

Variant appearance in text: PTEN: F243L
PubMed Link: 34557197
Variant Present in the following documents:
  • fimmu-12-737311.pdf
View BVdb publication page



Multi-omics profiling of primary small cell carcinoma of the esophagus reveals RB1 disruption and additional molecular subtypes.

Nature Communications
Li, Renda R; Yang, Zhenlin Z; Shao, Fei F; Cheng, Hong H; Wen, Yaru Y; Sun, Sijin S; Guo, Wei W; Li, Zitong Z; Zhang, Fan F; Xue, Liyan L; Bi, Nan N; Wang, Jie J; Sun, Yingli Y; Li, Yin Y; Tan, Fengwei F; Xue, Qi Q; Gao, Shugeng S; Shi, Susheng S; Gao, Yibo Y; He, Jie J
Publication Date: 2021-06-18

Variant appearance in text: PTEN: 727T>C; F243L
PubMed Link: 34145257
Variant Present in the following documents:
  • 41467_2021_24043_MOESM5_ESM.xlsx, sheet 1
View BVdb publication page



Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Publication Date: 2018

Variant appearance in text: PTEN: F243L
PubMed Link: 29698444
Variant Present in the following documents:
  • pone.0196434.s001.xlsx, sheet 3
  • pone.0196434.s001.xlsx, sheet 2
  • pone.0196434.s001.xlsx, sheet 1
View BVdb publication page



Amplicon sequencing of colorectal cancer: variant calling in frozen and formalin-fixed samples.

Plos One
Betge, Johannes J; Kerr, Grainne G; Miersch, Thilo T; Leible, Svenja S; Erdmann, Gerrit G; Galata, Christian L CL; Zhan, Tianzuo T; Gaiser, Timo T; Post, Stefan S; Ebert, Matthias P MP; Horisberger, Karoline K; Boutros, Michael M
Publication Date: 2015

Variant appearance in text: PTEN: F243L
PubMed Link: 26010451
Variant Present in the following documents:
  • pone.0127146.s014.xlsx, sheet 3
View BVdb publication page