Publications:

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Heterogeneity of the cancer cell line metabolic landscape.

Molecular Systems Biology

Shorthouse, David D; Bradley, Jenna J; Critchlow, Susan E SE; Bendtsen, Claus C; Hall, Benjamin A BA

Publication Date: 2022-11

Variant appearance in text: PTEN: 821delG; Val275fs*1

PubMed Link: 36321551

Variant Present in the following documents:

• MSB-18-e11006-s010.xlsx, sheet 1

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Combined p53- and PTEN-deficiency activates expression of mesenchyme homeobox 1 (MEOX1) required for growth of triple-negative breast cancer.

The Journal Of Biological Chemistry

Gasparyan, Mari M; Lo, Miao-Chia MC; Jiang, Hui H; Lin, Chang-Ching CC; Sun, Duxin D

Publication Date: 2020-08-21

Variant appearance in text: PTEN: 823delG; V275fsX1

PubMed Link: 32467227

Variant Present in the following documents:

• Main text

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Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen.

Nature Communications

Menden, Michael P MP; Wang, Dennis D; Mason, Mike J MJ; Szalai, Bence B; Bulusu, Krishna C KC; Guan, Yuanfang Y; Yu, Thomas T; Kang, Jaewoo J; Jeon, Minji M; Wolfinger, Russ R; Nguyen, Tin T; Zaslavskiy, Mikhail M; , ; Jang, In Sock IS; Ghazoui, Zara Z; Ahsen, Mehmet Eren ME; Vogel, Robert R; Neto, Elias Chaibub EC; Norman, Thea T; Tang, Eric K Y EKY; Garnett, Mathew J MJ; Veroli, Giovanni Y Di GYD; Fawell, Stephen S; Stolovitzky, Gustavo G; Guinney, Justin J; Dry, Jonathan R JR; Saez-Rodriguez, Julio J

Publication Date: 2019-06-17

Variant appearance in text: PTEN: V275fs*1

PubMed Link: 31209238

Variant Present in the following documents:

• 41467_2019_9799_MOESM5_ESM.xlsx, sheet 1

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Oncogenic PIK3CA mutations increase dependency on the mRNA cap methyltransferase, RNMT, in breast cancer cells.

Open Biology

Dunn, Sianadh S; Lombardi, Olivia O; Lukoszek, Radoslaw R; Cowling, Victoria H VH

Publication Date: 2019-04-26

Variant appearance in text: PTEN: 823delG; V275fs*1

PubMed Link: 30991934

Variant Present in the following documents:

• Main text

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Pan-urologic cancer genomic subtypes that transcend tissue of origin.

Nature Communications

Chen, Fengju F; Zhang, Yiqun Y; Bossé, Dominick D; Lalani, Aly-Khan A AA; Hakimi, A Ari AA; Hsieh, James J JJ; Choueiri, Toni K TK; Gibbons, Don L DL; Ittmann, Michael M; Creighton, Chad J CJ

Publication Date: 2017-08-04

Variant appearance in text: PTEN: 821delG; V275fs*1

PubMed Link: 28775315

Variant Present in the following documents:

• 41467_2017_289_MOESM7_ESM.xlsx, sheet 1

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Analytical Validation of the Next-Generation Sequencing Assay for a Nationwide Signal-Finding Clinical Trial: Molecular Analysis for Therapy Choice Clinical Trial.

The Journal Of Molecular Diagnostics : Jmd

Lih, Chih-Jian CJ; Harrington, Robin D RD; Sims, David J DJ; Harper, Kneshay N KN; Bouk, Courtney H CH; Datta, Vivekananda V; Yau, Jonathan J; Singh, Rajesh R RR; Routbort, Mark J MJ; Luthra, Rajyalakshmi R; Patel, Keyur P KP; Mantha, Geeta S GS; Krishnamurthy, Savitri S; Ronski, Karyn K; Walther, Zenta Z; Finberg, Karin E KE; Canosa, Sandra S; Robinson, Hayley H; Raymond, Amelia A; Le, Long P LP; McShane, Lisa M LM; Polley, Eric C EC; Conley, Barbara A BA; Doroshow, James H JH; Iafrate, A John AJ; Sklar, Jeffrey L JL; Hamilton, Stanley R SR; Williams, P Mickey PM

Publication Date: 2017-03

Variant appearance in text: PTEN: 821delG

PubMed Link: 28188106

Variant Present in the following documents:

• Main text

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A Landscape of Pharmacogenomic Interactions in Cancer.

Cell

Iorio, Francesco F; Knijnenburg, Theo A TA; Vis, Daniel J DJ; Bignell, Graham R GR; Menden, Michael P MP; Schubert, Michael M; Aben, Nanne N; Gonçalves, Emanuel E; Barthorpe, Syd S; Lightfoot, Howard H; Cokelaer, Thomas T; Greninger, Patricia P; van Dyk, Ewald E; Chang, Han H; de Silva, Heshani H; Heyn, Holger H; Deng, Xianming X; Egan, Regina K RK; Liu, Qingsong Q; Mironenko, Tatiana T; Mitropoulos, Xeni X; Richardson, Laura L; Wang, Jinhua J; Zhang, Tinghu T; Moran, Sebastian S; Sayols, Sergi S; Soleimani, Maryam M; Tamborero, David D; Lopez-Bigas, Nuria N; Ross-Macdonald, Petra P; Esteller, Manel M; Gray, Nathanael S NS; Haber, Daniel A DA; Stratton, Michael R MR; Benes, Cyril H CH; Wessels, Lodewyk F A LFA; Saez-Rodriguez, Julio J; McDermott, Ultan U; Garnett, Mathew J MJ

Publication Date: 2016-07-28

Variant appearance in text: PTEN: 821delG; V275fs*1

PubMed Link: 27397505

Variant Present in the following documents:

• mmc3.xlsx, sheet 3

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Target enrichment using parallel nanoliter quantitative PCR amplification.

Bmc Genomics

De Wilde, Bram B; Lefever, Steve S; Dong, Wes W; Dunne, Jude J; Husain, Syed S; Derveaux, Stefaan S; Hellemans, Jan J; Vandesompele, Jo J

Publication Date: 2014-03-10

Variant appearance in text: PTEN: 823delG; V275fs*1

PubMed Link: 24612714

Variant Present in the following documents:

• Main text
• 1471-2164-15-184.pdf

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