PTEN c.1031A>G ;(p.K344R)

Variant ID: 10-89725048-A-G

NM_000314.4(PTEN):c.1031A>G;(p.K344R)

This variant was identified in 9 publications

View GRCh38 version.




Publications:


Genomic landscape, immune characteristics and prognostic mutation signature of cervical cancer in China.

Bmc Medical Genomics
Liu, Jing J; Li, Zirong Z; Lu, Ting T; Pan, Junping J; Li, Li L; Song, Yanwen Y; Hu, Dan D; Zhuo, Yanhong Y; Chen, Ying Y; Xu, Qin Q
Publication Date: 2022-11-04

Variant appearance in text: PTEN: 1031A>G; K344R
PubMed Link: 36333792
Variant Present in the following documents:
  • 12920_2022_1376_MOESM1_ESM.xlsx, sheet 1
View BVdb publication page



Molecular correlates and therapeutic targets in T cell-inflamed versus non-T cell-inflamed tumors across cancer types.

Genome Medicine
Bao, Riyue R; Stapor, Daniel D; Luke, Jason J JJ
Publication Date: 2020-10-27

Variant appearance in text: PTEN: K344R
PubMed Link: 33106165
Variant Present in the following documents:
  • 13073_2020_787_MOESM1_ESM.xlsx, sheet 9
View BVdb publication page



Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway.

Science (New York, N.Y.)
Lee, Yu-Ru YR; Chen, Ming M; Lee, Jonathan D JD; Zhang, Jinfang J; Lin, Shu-Yu SY; Fu, Tian-Min TM; Chen, Hao H; Ishikawa, Tomoki T; Chiang, Shang-Yin SY; Katon, Jesse J; Zhang, Yang Y; Shulga, Yulia V YV; Bester, Assaf C AC; Fung, Jacqueline J; Monteleone, Emanuele E; Wan, Lixin L; Shen, Chen C; Hsu, Chih-Hung CH; Papa, Antonella A; Clohessy, John G JG; Teruya-Feldstein, Julie J; Jain, Suresh S; Wu, Hao H; Matesic, Lydia L; Chen, Ruey-Hwa RH; Wei, Wenyi W; Pandolfi, Pier Paolo PP
Publication Date: 2019-05-17

Variant appearance in text: PTEN: K344R
PubMed Link: 31097636
Variant Present in the following documents:
  • Main text
View BVdb publication page



Impact of p85α Alterations in Cancer.

Biomolecules
Marshall, Jeremy D S JDS; Whitecross, Dielle E DE; Mellor, Paul P; Anderson, Deborah H DH
Publication Date: 2019-01-15

Variant appearance in text: PTEN: K344R
PubMed Link: 30650664
Variant Present in the following documents:
  • Main text
  • biomolecules-09-00029.pdf
View BVdb publication page



Pan-urologic cancer genomic subtypes that transcend tissue of origin.

Nature Communications
Chen, Fengju F; Zhang, Yiqun Y; Bossé, Dominick D; Lalani, Aly-Khan A AA; Hakimi, A Ari AA; Hsieh, James J JJ; Choueiri, Toni K TK; Gibbons, Don L DL; Ittmann, Michael M; Creighton, Chad J CJ
Publication Date: 2017-08-04

Variant appearance in text: PTEN: 1031A>G; K344R
PubMed Link: 28775315
Variant Present in the following documents:
  • 41467_2017_289_MOESM7_ESM.xlsx, sheet 1
View BVdb publication page



A Landscape of Pharmacogenomic Interactions in Cancer.

Cell
Iorio, Francesco F; Knijnenburg, Theo A TA; Vis, Daniel J DJ; Bignell, Graham R GR; Menden, Michael P MP; Schubert, Michael M; Aben, Nanne N; Gonçalves, Emanuel E; Barthorpe, Syd S; Lightfoot, Howard H; Cokelaer, Thomas T; Greninger, Patricia P; van Dyk, Ewald E; Chang, Han H; de Silva, Heshani H; Heyn, Holger H; Deng, Xianming X; Egan, Regina K RK; Liu, Qingsong Q; Mironenko, Tatiana T; Mitropoulos, Xeni X; Richardson, Laura L; Wang, Jinhua J; Zhang, Tinghu T; Moran, Sebastian S; Sayols, Sergi S; Soleimani, Maryam M; Tamborero, David D; Lopez-Bigas, Nuria N; Ross-Macdonald, Petra P; Esteller, Manel M; Gray, Nathanael S NS; Haber, Daniel A DA; Stratton, Michael R MR; Benes, Cyril H CH; Wessels, Lodewyk F A LFA; Saez-Rodriguez, Julio J; McDermott, Ultan U; Garnett, Mathew J MJ
Publication Date: 2016-07-28

Variant appearance in text: PTEN: 1031A>G; K344R
PubMed Link: 27397505
Variant Present in the following documents:
  • mmc3.xlsx, sheet 2
View BVdb publication page



Protein domain-level landscape of cancer-type-specific somatic mutations.

Plos Computational Biology
Yang, Fan F; Petsalaki, Evangelia E; Rolland, Thomas T; Hill, David E DE; Vidal, Marc M; Roth, Frederick P FP
Publication Date: 2015-03

Variant appearance in text: PTEN: K344R
PubMed Link: 25794154
Variant Present in the following documents:
  • pcbi.1004147.s001.xlsx, sheet 1
View BVdb publication page



Genomic Rearrangements of PTEN in Prostate Cancer.

Frontiers In Oncology
Phin, Sopheap S; Moore, Mathew W MW; Cotter, Philip D PD
Publication Date: 2013-09-17

Variant appearance in text: PTEN: K344R
PubMed Link: 24062990
Variant Present in the following documents:
  • Main text
  • fonc-03-00240.pdf
View BVdb publication page



Predicting the functional impact of protein mutations: application to cancer genomics.

Nucleic Acids Research
Reva, Boris B; Antipin, Yevgeniy Y; Sander, Chris C
Publication Date: 2011-09-01

Variant appearance in text: PTEN: K344R
PubMed Link: 21727090
Variant Present in the following documents:
  • supp_gkr407_Supplement2_Table_SM1_COSMIC_mutations.xls, sheet 1
View BVdb publication page