Publications:

Grb2 binds to PTEN and regulates its nuclear translocation to maintain the genomic stability in DNA damage response.

Cell Death & Disease

Hou, Bolin B; Xu, Shanshan S; Xu, Yang Y; Gao, Quan Q; Zhang, Caining C; Liu, Ling L; Yang, Huaiyi H; Jiang, Xuejun X; Che, Yongsheng Y

Publication Date: 2019-07-18

Variant appearance in text: PTEN: T398A

PubMed Link: 31320611

Variant Present in the following documents:

• Main text

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PTEN Methylation by NSD2 Controls Cellular Sensitivity to DNA Damage.

Cancer Discovery

Zhang, Jinfang J; Lee, Yu-Ru YR; Dang, Fabin F; Gan, Wenjian W; Menon, Archita Venugopal AV; Katon, Jesse M JM; Hsu, Chih-Hung CH; Asara, John M JM; Tibarewal, Priyanka P; Leslie, Nicholas R NR; Shi, Yang Y; Pandolfi, Pier Paolo PP; Wei, Wenyi W

Publication Date: 2019-09

Variant appearance in text: PTEN: T398A

PubMed Link: 31217297

Variant Present in the following documents:

• Main text

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Precise definition of PTEN C-terminal epitopes and its implications in clinical oncology.

Npj Precision Oncology

Mingo, Janire J; Luna, Sandra S; Gaafar, Ayman A; Nunes-Xavier, Caroline E CE; Torices, Leire L; Mosteiro, Lorena L; Ruiz, Rebeca R; Guerra, Isabel I; Llarena, Roberto R; Angulo, Javier C JC; López, José I JI; Pulido, Rafael R

Publication Date: 2019

Variant appearance in text: PTEN: T398A

PubMed Link: 30993208

Variant Present in the following documents:

• Main text
• 41698_2019_83_MOESM1_ESM.pdf
• 41698_2019_Article_83.pdf

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ATM-mediated PTEN phosphorylation promotes PTEN nuclear translocation and autophagy in response to DNA-damaging agents in cancer cells.

Autophagy

Chen, Jing-Hong JH; Zhang, Peng P; Chen, Wen-Dan WD; Li, Dan-Dan DD; Wu, Xiao-Qi XQ; Deng, Rong R; Jiao, Lin L; Li, Xuan X; Ji, Jiao J; Feng, Gong-Kan GK; Zeng, Yi-Xin YX; Jiang, Jian-Wei JW; Zhu, Xiao-Feng XF

Publication Date: 2015

Variant appearance in text: PTEN: T398A

PubMed Link: 25701194

Variant Present in the following documents:

• Main text

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Nuclear PTEN controls DNA repair and sensitivity to genotoxic stress.

Science (New York, N.Y.)

Bassi, C C; Ho, J J; Srikumar, T T; Dowling, R J O RJ; Gorrini, C C; Miller, S J SJ; Mak, T W TW; Neel, B G BG; Raught, B B; Stambolic, V V

Publication Date: 2013-07-26

Variant appearance in text: PTEN: T398A

PubMed Link: 23888040

Variant Present in the following documents:

• Main text

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