Identification of antigenic epitopes recognized by tumor infiltrating lymphocytes in high grade serous ovarian cancer by multi-omics profiling of the auto-antigen repertoire.
Cancer Immunology, Immunotherapy : Cii
Millar, Douglas G DG; Yang, S Y Cindy SYC; Sayad, Azin A; Zhao, Qingchuan Q; Nguyen, Linh T LT; Warner, Kathrin K; Sangster, Ami G AG; Nakatsugawa, Munehide M; Murata, Kenji K; Wang, Ben X BX; Shaw, Patricia P; Clarke, Blaise B; Bernardini, Marcus Q MQ; Pugh, Trevor T; Thibault, Pierre P; Hirano, Naoto N; Perreault, Claude C; Ohashi, Pamela S PS
A Phase II Trial of Guadecitabine plus Atezolizumab in Metastatic Urothelial Carcinoma Progressing after Initial Immune Checkpoint Inhibitor Therapy.
Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Jang, H Josh HJ; Hostetter, Galen G; MacFarlane, Alexander W AW; Madaj, Zachary Z; Ross, Eric A EA; Hinoue, Toshinori T; Kulchycki, Justin R JR; Burgos, Ryan S RS; Tafseer, Mahvish M; Alpaugh, R Katherine RK; Schwebel, Candice L CL; Kokate, Rutika R; Geynisman, Daniel M DM; Zibelman, Matthew R MR; Ghatalia, Pooja P; Nichols, Peter W PW; Chung, Woonbok W; Madzo, Jozef J; Hahn, Noah M NM; Quinn, David I DI; Issa, Jean-Pierre J JJ; Topper, Michael J MJ; Baylin, Stephen B SB; Shen, Hui H; Campbell, Kerry S KS; Jones, Peter A PA; Plimack, Elizabeth R ER
Genome-wide analyses of 200,453 individuals yield new insights into the causes and consequences of clonal hematopoiesis.
Nature Genetics
Kar, Siddhartha P SP; Quiros, Pedro M PM; Gu, Muxin M; Jiang, Tao T; Mitchell, Jonathan J; Langdon, Ryan R; Iyer, Vivek V; Barcena, Clea C; Vijayabaskar, M S MS; Fabre, Margarete A MA; Carter, Paul P; Petrovski, Slavé S; Burgess, Stephen S; Vassiliou, George S GS
Serial monitoring of genomic alterations in circulating tumor cells of ER-positive/HER2-negative advanced breast cancer: feasibility of precision oncology biomarker detection.
Molecular Oncology
Cani, Andi K AK; Dolce, Emily M EM; Darga, Elizabeth P EP; Hu, Kevin K; Liu, Chia-Jen CJ; Pierce, Jackie J; Bradbury, Kieran K; Kilgour, Elaine E; Aung, Kimberly K; Schiavon, Gaia G; Carroll, Danielle D; Carr, T Hedley TH; Klinowska, Teresa T; Lindemann, Justin J; Marshall, Gayle G; Rowlands, Vicky V; Harrington, Elizabeth A EA; Barrett, J Carl JC; Sathiyayogan, Nitharsan N; Morrow, Christopher C; Sero, Valeria V; Armstrong, Anne C AC; Baird, Richard R; Hamilton, Erika E; Im, Seock-Ah SA; Jhaveri, Komal K; Patel, Manish R MR; Dive, Caroline C; Tomlins, Scott A SA; Udager, Aaron M AM; Hayes, Daniel F DF; Paoletti, Costanza C
Molecular genomic features associated with in vitro response of the NCI-60 cancer cell line panel to natural products.
Molecular Oncology
Krushkal, Julia J; Negi, Simarjeet S; Yee, Laura M LM; Evans, Jason R JR; Grkovic, Tanja T; Palmisano, Alida A; Fang, Jianwen J; Sankaran, Hari H; McShane, Lisa M LM; Zhao, Yingdong Y; O'Keefe, Barry R BR
NF1 patient missense variants predict a role for ATM in modifying neurofibroma initiation.
Acta Neuropathologica
Yu, Yanan Y; Choi, Kwangmin K; Wu, Jianqiang J; Andreassen, Paul R PR; Dexheimer, Phillip J PJ; Keddache, Mehdi M; Brems, Hilde H; Spinner, Robert J RJ; Cancelas, Jose A JA; Martin, Lisa J LJ; Wallace, Margaret R MR; Legius, Eric E; Vogel, Kristine S KS; Ratner, Nancy N
Serial patient-derived orthotopic xenografting of adenoid cystic carcinomas recapitulates stable expression of phenotypic alterations and innervation.
Ebiomedicine
Cornett, Ashley A; Athwal, Harleen K HK; Hill, Emily E; Murphy, George G; Yeoh, Kenji K; Moskaluk, Christopher A CA; Witt, Robert L RL; D'Silva, Nisha J NJ; Agarwal, Seema S; Lombaert, Isabelle M A IMA
Optimized creation of glioblastoma patient derived xenografts for use in preclinical studies.
Journal Of Translational Medicine
William, Doreen D; Mullins, Christina Susanne CS; Schneider, Björn B; Orthmann, Andrea A; Lamp, Nora N; Krohn, Mathias M; Hoffmann, Annika A; Classen, Carl-Friedrich CF; Linnebacher, Michael M
MEK inhibitors block growth of lung tumours with mutations in ataxia-telangiectasia mutated.
Nature Communications
Smida, Michal M; Fece de la Cruz, Ferran F; Kerzendorfer, Claudia C; Uras, Iris Z IZ; Mair, Barbara B; Mazouzi, Abdelghani A; Suchankova, Tereza T; Konopka, Tomasz T; Katz, Amanda M AM; Paz, Keren K; Nagy-Bojarszky, Katalin K; Muellner, Markus K MK; Bago-Horvath, Zsuzsanna Z; Haura, Eric B EB; Loizou, Joanna I JI; Nijman, Sebastian M B SM
Validation and utilisation of high-coverage next-generation sequencing to deliver the pharmacological audit trail.
British Journal Of Cancer
Ong, M M; Carreira, S S; Goodall, J J; Mateo, J J; Figueiredo, I I; Rodrigues, D N DN; Perkins, G G; Seed, G G; Yap, T A TA; Attard, G G; de Bono, J S JS
Integrated analysis of germline and somatic variants in ovarian cancer.
Nature Communications
Kanchi, Krishna L KL; Johnson, Kimberly J KJ; Lu, Charles C; McLellan, Michael D MD; Leiserson, Mark D M MD; Wendl, Michael C MC; Zhang, Qunyuan Q; Koboldt, Daniel C DC; Xie, Mingchao M; Kandoth, Cyriac C; McMichael, Joshua F JF; Wyczalkowski, Matthew A MA; Larson, David E DE; Schmidt, Heather K HK; Miller, Christopher A CA; Fulton, Robert S RS; Spellman, Paul T PT; Mardis, Elaine R ER; Druley, Todd E TE; Graubert, Timothy A TA; Goodfellow, Paul J PJ; Raphael, Benjamin J BJ; Wilson, Richard K RK; Ding, Li L
Identification of nine genomic regions of amplification in urothelial carcinoma, correlation with stage, and potential prognostic and therapeutic value.
Plos One
Chekaluk, Yvonne Y; Wu, Chin-Lee CL; Rosenberg, Jonathan J; Riester, Markus M; Dai, Qishan Q; Lin, Sharron S; Guo, Yanan Y; McDougal, W Scott WS; Kwiatkowski, David J DJ
Low expression levels of ATM may substitute for CHEK2 /TP53 mutations predicting resistance towards anthracycline and mitomycin chemotherapy in breast cancer.
Breast Cancer Research : Bcr
Knappskog, Stian S; Chrisanthar, Ranjan R; Løkkevik, Erik E; Anker, Gun G; Østenstad, Bjørn B; Lundgren, Steinar S; Risberg, Terje T; Mjaaland, Ingvil I; Leirvaag, Beryl B; Miletic, Hrvoje H; Lønning, Per E PE
ATM polymorphisms as risk factors for prostate cancer development.
British Journal Of Cancer
Angèle, S S; Falconer, A A; Edwards, S M SM; Dörk, T T; Bremer, M M; Moullan, N N; Chapot, B B; Muir, K K; Houlston, R R; Norman, A R AR; Bullock, S S; Hope, Q Q; Meitz, J J; Dearnaley, D D; Dowe, A A; Southgate, C C; Ardern-Jones, A A; Easton, D F DF; Eeles, R A RA; Hall, J J
Oligonucleotide microarrays demonstrate the highest frequency of ATM mutations in the mantle cell subtype of lymphoma.
Proceedings Of The National Academy Of Sciences Of The United States Of America
Fang, Nicole Y NY; Greiner, Timothy C TC; Weisenburger, Dennis D DD; Chan, Wing C WC; Vose, Julie M JM; Smith, Lynette M LM; Armitage, James O JO; Mayer, R Aeryn RA; Pike, Brian L BL; Collins, Francis S FS; Hacia, Joseph G JG