Detection of pleiotropy through a Phenome-wide association study (PheWAS) of epidemiologic data as part of the Environmental Architecture for Genes Linked to Environment (EAGLE) study.
Plos Genetics
Hall, Molly A MA; Verma, Anurag A; Brown-Gentry, Kristin D KD; Goodloe, Robert R; Boston, Jonathan J; Wilson, Sarah S; McClellan, Bob B; Sutcliffe, Cara C; Dilks, Holly H HH; Gillani, Nila B NB; Jin, Hailing H; Mayo, Ping P; Allen, Melissa M; Schnetz-Boutaud, Nathalie N; Crawford, Dana C DC; Ritchie, Marylyn D MD; Pendergrass, Sarah A SA
Lipid trait-associated genetic variation is associated with gallstone disease in the diverse Third National Health and Nutrition Examination Survey (NHANES III).
Bmc Medical Genetics
Goodloe, Robert R; Brown-Gentry, Kristin K; Gillani, Niloufar B NB; Jin, Hailing H; Mayo, Ping P; Allen, Melissa M; McClellan, Bob B; Boston, Jonathan J; Sutcliffe, Cara C; Schnetz-Boutaud, Nathalie N; Dilks, Holli H HH; Crawford, Dana C DC
Generalization and dilution of association results from European GWAS in populations of non-European ancestry: the PAGE study.
Plos Biology
Carlson, Christopher S CS; Matise, Tara C TC; North, Kari E KE; Haiman, Christopher A CA; Fesinmeyer, Megan D MD; Buyske, Steven S; Schumacher, Fredrick R FR; Peters, Ulrike U; Franceschini, Nora N; Ritchie, Marylyn D MD; Duggan, David J DJ; Spencer, Kylee L KL; Dumitrescu, Logan L; Eaton, Charles B CB; Thomas, Fridtjof F; Young, Alicia A; Carty, Cara C; Heiss, Gerardo G; Le Marchand, Loic L; Crawford, Dana C DC; Hindorff, Lucia A LA; Kooperberg, Charles L CL; ,
Genetic association with lipids in Filipinos: waist circumference modifies an APOA5 effect on triglyceride levels.
Journal Of Lipid Research
Wu, Ying Y; Marvelle, Amanda F AF; Li, Jin J; Croteau-Chonka, Damien C DC; Feranil, Alan B AB; Kuzawa, Christopher W CW; Li, Yun Y; Adair, Linda S LS; Mohlke, Karen L KL
Investigation of gene-by-sex interactions for lipid traits in diverse populations from the population architecture using genomics and epidemiology study.
Bmc Genetics
Taylor, Kira C KC; Carty, Cara L CL; Dumitrescu, Logan L; Bůžková, Petra P; Cole, Shelley A SA; Hindorff, Lucia L; Schumacher, Fred R FR; Wilkens, Lynne R LR; Shohet, Ralph V RV; Quibrera, P Miguel PM; Johnson, Karen C KC; Henderson, Brian E BE; Haessler, Jeff J; Franceschini, Nora N; Eaton, Charles B CB; Duggan, David J DJ; Cochran, Barbara B; Cheng, Iona I; Carlson, Chris S CS; Brown-Gentry, Kristin K; Anderson, Garnet G; Ambite, Jose Luis JL; Haiman, Christopher C; Le Marchand, Loïc L; Kooperberg, Charles C; Crawford, Dana C DC; Buyske, Steven S; North, Kari E KE; Fornage, Myriam M; ,
Hypothesis-based analysis of gene-gene interactions and risk of myocardial infarction.
Plos One
Lucas, Gavin G; Lluís-Ganella, Carla C; Subirana, Isaac I; Musameh, Muntaser D MD; Gonzalez, Juan Ramon JR; Nelson, Christopher P CP; Sentí, Mariano M; , ; , ; Schwartz, Stephen M SM; Siscovick, David D; O'Donnell, Christopher J CJ; Melander, Olle O; Salomaa, Veikko V; Purcell, Shaun S; Altshuler, David D; Samani, Nilesh J NJ; Kathiresan, Sekar S; Elosua, Roberto R
Genetic determinants of lipid traits in diverse populations from the population architecture using genomics and epidemiology (PAGE) study.
Plos Genetics
Dumitrescu, Logan L; Carty, Cara L CL; Taylor, Kira K; Schumacher, Fredrick R FR; Hindorff, Lucia A LA; Ambite, José L JL; Anderson, Garnet G; Best, Lyle G LG; Brown-Gentry, Kristin K; Bůžková, Petra P; Carlson, Christopher S CS; Cochran, Barbara B; Cole, Shelley A SA; Devereux, Richard B RB; Duggan, Dave D; Eaton, Charles B CB; Fornage, Myriam M; Franceschini, Nora N; Haessler, Jeff J; Howard, Barbara V BV; Johnson, Karen C KC; Laston, Sandra S; Kolonel, Laurence N LN; Lee, Elisa T ET; MacCluer, Jean W JW; Manolio, Teri A TA; Pendergrass, Sarah A SA; Quibrera, Miguel M; Shohet, Ralph V RV; Wilkens, Lynne R LR; Haiman, Christopher A CA; Le Marchand, Loïc L; Buyske, Steven S; Kooperberg, Charles C; North, Kari E KE; Crawford, Dana C DC
A polygenic basis for four classical Fredrickson hyperlipoproteinemia phenotypes that are characterized by hypertriglyceridemia.
Human Molecular Genetics
Hegele, Robert A RA; Ban, Matthew R MR; Hsueh, Neil N; Kennedy, Brooke A BA; Cao, Henian H; Zou, Guang Yong GY; Anand, Sonia S; Yusuf, Salim S; Huff, Murray W MW; Wang, Jian J
Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.
Nature Genetics
Kathiresan, Sekar S; Melander, Olle O; Guiducci, Candace C; Surti, Aarti A; Burtt, Noël P NP; Rieder, Mark J MJ; Cooper, Gregory M GM; Roos, Charlotta C; Voight, Benjamin F BF; Havulinna, Aki S AS; Wahlstrand, Björn B; Hedner, Thomas T; Corella, Dolores D; Tai, E Shyong ES; Ordovas, Jose M JM; Berglund, Göran G; Vartiainen, Erkki E; Jousilahti, Pekka P; Hedblad, Bo B; Taskinen, Marja-Riitta MR; Newton-Cheh, Christopher C; Salomaa, Veikko V; Peltonen, Leena L; Groop, Leif L; Altshuler, David M DM; Orho-Melander, Marju M