Publications:

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Genome-Wide Identification of Rare and Common Variants Driving Triglyceride Levels in a Nevada Population.

Frontiers In Genetics

Read, Robert W RW; Schlauch, Karen A KA; Lombardi, Vincent C VC; Cirulli, Elizabeth T ET; Washington, Nicole L NL; Lu, James T JT; Grzymski, Joseph J JJ

Publication Date: 2021

Variant appearance in text: rs12286037

PubMed Link: 33763119

Variant Present in the following documents:

• fgene-12-639418.pdf

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Gene-environment interactions due to quantile-specific heritability of triglyceride and VLDL concentrations.

Scientific Reports

Williams, Paul T PT

Publication Date: 2020-03-11

Variant appearance in text: rs12286037

PubMed Link: 32161301

Variant Present in the following documents:

• 41598_2020_Article_60965.pdf

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Allele-specific enhancers mediate associations between LCAT and ABCA1 polymorphisms and HDL metabolism.

Plos One

Howard, Alicia D AD; Wang, Xiaochun X; Prasad, Megana M; Sahu, Avinash Das AD; Aniba, Radhouane R; Miller, Michael M; Hannenhalli, Sridhar S; Chang, Yen-Pei Christy YC

Publication Date: 2019

Variant appearance in text: rs12286037

PubMed Link: 31039173

Variant Present in the following documents:

• Main text
• pone.0215911.pdf

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Frequency and phenotype consequence of APOC3 rare variants in patients with very low triglyceride levels.

Bmc Medical Genomics

Crawford, Dana C DC; Restrepo, Nicole A NA; Diggins, Kirsten E KE; Farber-Eger, Eric E; Wells, Quinn S QS

Publication Date: 2018-09-14

Variant appearance in text: rs12286037

PubMed Link: 30255797

Variant Present in the following documents:

• Main text

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New insights into apolipoprotein A5 in controlling lipoprotein metabolism in obesity and the metabolic syndrome patients.

Lipids In Health And Disease

Su, Xin X; Kong, Yi Y; Peng, Dao-Quan DQ

Publication Date: 2018-07-27

Variant appearance in text: rs12286037

PubMed Link: 30053818

Variant Present in the following documents:

• 12944_2018_Article_833.pdf

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Transforming growth factor-β signaling pathway-associated genes SMAD2 and TGFBR2 are implicated in metabolic syndrome in a Taiwanese population.

Scientific Reports

Lin, Eugene E; Kuo, Po-Hsiu PH; Liu, Yu-Li YL; Yang, Albert C AC; Tsai, Shih-Jen SJ

Publication Date: 2017-10-19

Variant appearance in text: rs12286037

PubMed Link: 29051557

Variant Present in the following documents:

• Main text
• 41598_2017_Article_14025.pdf

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Association of BUD13 polymorphisms with metabolic syndrome in Chinese population: a case-control study.

Lipids In Health And Disease

Zhang, Lili L; You, Yueyue Y; Wu, Yanhua Y; Zhang, Yangyu Y; Wang, Mohan M; Song, Yan Y; Liu, Xinyu X; Kou, Changgui C

Publication Date: 2017-06-28

Variant appearance in text: rs12286037

PubMed Link: 28659142

Variant Present in the following documents:

• Main text
• 12944_2017_Article_520.pdf

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Fine-mapping of lipid regions in global populations discovers ethnic-specific signals and refines previously identified lipid loci.

Human Molecular Genetics

Zubair, Niha N; Graff, Mariaelisa M; Luis Ambite, Jose J; Bush, William S WS; Kichaev, Gleb G; Lu, Yingchang Y; Manichaikul, Ani A; Sheu, Wayne H-H WH; Absher, Devin D; Assimes, Themistocles L TL; Bielinski, Suzette J SJ; Bottinger, Erwin P EP; Buzkova, Petra P; Chuang, Lee-Ming LM; Chung, Ren-Hua RH; Cochran, Barbara B; Dumitrescu, Logan L; Gottesman, Omri O; Haessler, Jeffrey W JW; Haiman, Christopher C; Heiss, Gerardo G; Hsiung, Chao A CA; Hung, Yi-Jen YJ; Hwu, Chii-Min CM; Juang, Jyh-Ming J JJ; Le Marchand, Loic L; Lee, I-Te IT; Lee, Wen-Jane WJ; Lin, Li-An LA; Lin, Danyu D; Lin, Shih-Yi SY; Mackey, Rachel H RH; Martin, Lisa W LW; Pasaniuc, Bogdan B; Peters, Ulrike U; Predazzi, Irene I; Quertermous, Thomas T; Reiner, Alex P AP; Robinson, Jennifer J; Rotter, Jerome I JI; Ryckman, Kelli K KK; Schreiner, Pamela J PJ; Stahl, Eli E; Tao, Ran R; Tsai, Michael Y MY; Waite, Lindsay L LL; Wang, Tzung-Dau TD; Buyske, Steven S; Ida Chen, Yii-Der YD; Cheng, Iona I; Crawford, Dana C DC; Loos, Ruth J F RJF; Rich, Stephen S SS; Fornage, Myriam M; North, Kari E KE; Kooperberg, Charles C; Carty, Cara L CL

Publication Date: 2016-12-15

Variant appearance in text: rs12286037

PubMed Link: 28426890

Variant Present in the following documents:

• Main text

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The APOA5 rs662799 polymorphism is associated with dyslipidemia and the severity of coronary heart disease in Chinese women.

Lipids In Health And Disease

Wang, Yanmei Y; Lu, Zhan Z; Zhang, Jingxiao J; Yang, Yang Y; Shen, Jing J; Zhang, Xiaoming X; Song, Yongyan Y

Publication Date: 2016-09-30

Variant appearance in text: rs12286037

PubMed Link: 27716220

Variant Present in the following documents:

• 12944_2016_Article_343.pdf

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Two-stage association study to identify the genetic susceptibility of a novel common variant of rs2075290 in ZPR1 to type 2 diabetes.

Scientific Reports

Guan, Fanglin F; Niu, Yu Y; Zhang, Tianxiao T; Liu, Songfang S; Ma, Lei L; Qi, Ting T; Feng, Jia J; Zuo, Hong H; Li, Guohong G; Liu, Xufeng X; Wang, Shujin S

Publication Date: 2016-07-14

Variant appearance in text: rs12286037

PubMed Link: 27411854

Variant Present in the following documents:

• Main text

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Distinct Patterns of Association of Variants at 11q23.3 Chromosomal Region with Coronary Artery Disease and Dyslipidemia in the Population of Andhra Pradesh, India.

Plos One

Pranav Chand, Rayabarapu R; Kumar, Arramraju Sreenivas AS; Anuj, Kapadia K; Vishnupriya, Satti S; Mohan Reddy, Battini B

Publication Date: 2016

Variant appearance in text: rs12286037

PubMed Link: 27257688

Variant Present in the following documents:

• Main text
• pone.0153720.pdf

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The interaction of Apolipoprotein A5 gene promoter region T-1131C polymorphism (rs12286037) and lifestyle modification on plasma triglyceride levels in Japanese.

Nutrition Research And Practice

Yamasaki, Masayuki M; Mutombo, Paulin Beya Wa Bitadi PB; Iwamoto, Mamiko M; Nogi, Akiko A; Hashimoto, Michio M; Nabika, Toru T; Shiwaku, Kuninori K

Publication Date: 2015-08

Variant appearance in text: rs12286037

PubMed Link: 26244076

Variant Present in the following documents:

• Main text
• nrp-9-379.pdf

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Gene-centric association signals for haemostasis and thrombosis traits identified with the HumanCVD BeadChip.

Thrombosis And Haemostasis

Gaunt, Tom R TR; Zabaneh, Delilah D; Shah, Sonia S; Guyatt, Anna A; Ladroue, Christophe C; Kumari, Meena M; Drenos, Fotios F; Shah, Tina T; Talmud, Philippa J PJ; Casas, Juan Pablo JP; Lowe, Gordon G; Rumley, Ann A; Lawlor, Debbie A DA; Kivimaki, Mika M; Whittaker, John J; Hingorani, Aroon D AD; Humphries, Steve E SE; Day, Ian N IN

Publication Date: 2013-11

Variant appearance in text: rs12286037

PubMed Link: 24178511

Variant Present in the following documents:

• Main text

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Genetic association with lipids in Filipinos: waist circumference modifies an APOA5 effect on triglyceride levels.

Journal Of Lipid Research

Wu, Ying Y; Marvelle, Amanda F AF; Li, Jin J; Croteau-Chonka, Damien C DC; Feranil, Alan B AB; Kuzawa, Christopher W CW; Li, Yun Y; Adair, Linda S LS; Mohlke, Karen L KL

Publication Date: 2013-11

Variant appearance in text: rs12286037

PubMed Link: 24023260

Variant Present in the following documents:

• Main text

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Do genetic modifiers of high-density lipoprotein cholesterol and triglyceride levels also modify their response to a lifestyle intervention in the setting of obesity and type-2 diabetes mellitus?: The Action for Health in Diabetes (Look AHEAD) study.

Circulation. Cardiovascular Genetics

Huggins, Gordon S GS; Papandonatos, George D GD; Erar, Bahar B; Belalcazar, L Maria LM; Brautbar, Ariel A; Ballantyne, Christie C; Kitabchi, Abbas E AE; Wagenknecht, Lynne E LE; Knowler, William C WC; Pownall, Henry J HJ; Wing, Rena R RR; Peter, Inga I; McCaffery, Jeanne M JM; ,

Publication Date: 2013-08

Variant appearance in text: rs12286037

PubMed Link: 23861364

Variant Present in the following documents:

• Main text

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Single nucleotide polymorphisms (SNPs) involved in insulin resistance, weight regulation, lipid metabolism and inflammation in relation to metabolic syndrome: an epidemiological study.

Cardiovascular Diabetology

Povel, Cécile M CM; Boer, Jolanda M A JM; Onland-Moret, N Charlotte NC; Dollé, Martijn E T ME; Feskens, Edith J M EJ; van der Schouw, Yvonne T YT

Publication Date: 2012-10-29

Variant appearance in text: rs12286037

PubMed Link: 23101478

Variant Present in the following documents:

• Main text

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Shared ancestral susceptibility to colorectal cancer and other nutrition related diseases.

Bmc Medical Genetics

Huhn, Stefanie S; Bevier, Melanie M; Rudolph, Anja A; Pardini, Barbara B; Naccarati, Alessio A; Hein, Rebecca R; Hoffmeister, Michael M; Vodickova, Ludmila L; Novotny, Jan J; Brenner, Hermann H; Chang-Claude, Jenny J; Hemminki, Kari K; Vodicka, Pavel P; Försti, Asta A

Publication Date: 2012-10-05

Variant appearance in text: rs12286037

PubMed Link: 23036011

Variant Present in the following documents:

• 1471-2350-13-94-S1.pdf

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A replication study of GWAS-derived lipid genes in Asian Indians: the chromosomal region 11q23.3 harbors loci contributing to triglycerides.

Plos One

Braun, Timothy R TR; Been, Latonya F LF; Singhal, Akhil A; Worsham, Jacob J; Ralhan, Sarju S; Wander, Gurpreet S GS; Chambers, John C JC; Kooner, Jaspal S JS; Aston, Christopher E CE; Sanghera, Dharambir K DK

Publication Date: 2012

Variant appearance in text: rs12286037

PubMed Link: 22623978

Variant Present in the following documents:

• Main text
• pone.0037056.pdf

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Implications of discoveries from genome-wide association studies in current cardiovascular practice.

World Journal Of Cardiology

Jeemon, Panniyammakal P; Pettigrew, Kerry K; Sainsbury, Christopher C; Prabhakaran, Dorairaj D; Padmanabhan, Sandosh S

Publication Date: 2011-07-26

Variant appearance in text: rs12286037

PubMed Link: 21860704

Variant Present in the following documents:

• Main text

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Validation of candidate genes associated with cardiovascular risk factors in psychiatric patients.

Progress In Neuro-Psychopharmacology & Biological Psychiatry

Windemuth, Andreas A; de Leon, Jose J; Goethe, John W JW; Schwartz, Harold I HI; Woolley, Stephen S; Susce, Margaret M; Kocherla, Mohan M; Bogaard, Kali K; Holford, Theodore R TR; Seip, Richard L RL; Ruaño, Gualberto G

Publication Date: 2012-03-30

Variant appearance in text: rs12286037

PubMed Link: 21851846

Variant Present in the following documents:

• Main text

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A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.

Diabetes

Kraja, Aldi T AT; Vaidya, Dhananjay D; Pankow, James S JS; Goodarzi, Mark O MO; Assimes, Themistocles L TL; Kullo, Iftikhar J IJ; Sovio, Ulla U; Mathias, Rasika A RA; Sun, Yan V YV; Franceschini, Nora N; Absher, Devin D; Li, Guo G; Zhang, Qunyuan Q; Feitosa, Mary F MF; Glazer, Nicole L NL; Haritunians, Talin T; Hartikainen, Anna-Liisa AL; Knowles, Joshua W JW; North, Kari E KE; Iribarren, Carlos C; Kral, Brian B; Yanek, Lisa L; O'Reilly, Paul F PF; McCarthy, Mark I MI; Jaquish, Cashell C; Couper, David J DJ; Chakravarti, Aravinda A; Psaty, Bruce M BM; Becker, Lewis C LC; Province, Michael A MA; Boerwinkle, Eric E; Quertermous, Thomas T; Palotie, Leena L; Jarvelin, Marjo-Riitta MR; Becker, Diane M DM; Kardia, Sharon L R SL; Rotter, Jerome I JI; Chen, Yii-Der Ida YD; Borecki, Ingrid B IB

Publication Date: 2011-04

Variant appearance in text: rs12286037

PubMed Link: 21386085

Variant Present in the following documents:

• Main text
• 1329.pdf

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Genome-wide significant associations for variants with minor allele frequency of 5% or less--an overview: A HuGE review.

American Journal Of Epidemiology

Panagiotou, Orestis A OA; Evangelou, Evangelos E; Ioannidis, John P A JP

Publication Date: 2010-10-15

Variant appearance in text: rs12286037

PubMed Link: 20876667

Variant Present in the following documents:

• Main text

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A single nucleotide polymorphism in APOA5 determines triglyceride levels in Hong Kong and Guangzhou Chinese.

European Journal Of Human Genetics : Ejhg

Jiang, Chao Qiang CQ; Liu, Bin B; Cheung, Bernard M Y BM; Lam, Tai Hing TH; Lin, Jie Ming JM; Li Jin, Ya Y; Yue, Xiao Jun XJ; Ong, Kwok Leung KL; Tam, Sidney S; Wong, Ka Sing KS; Tomlinson, Brian B; Lam, Karen S L KS; Thomas, G Neil GN

Publication Date: 2010-11

Variant appearance in text: rs12286037

PubMed Link: 20571505

Variant Present in the following documents:

• Main text

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Genome-wide association study of Lp-PLA(2) activity and mass in the Framingham Heart Study.

Plos Genetics

Suchindran, Sunil S; Rivedal, David D; Guyton, John R JR; Milledge, Tom T; Gao, Xiaoyi X; Benjamin, Ashlee A; Rowell, Jennifer J; Ginsburg, Geoffrey S GS; McCarthy, Jeanette J JJ

Publication Date: 2010-04-29

Variant appearance in text: rs12286037

PubMed Link: 20442857

Variant Present in the following documents:

• Main text

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The genetics of obesity and the metabolic syndrome.

Endocrine, Metabolic & Immune Disorders Drug Targets

Monda, Keri L KL; North, Kari E KE; Hunt, Steven C SC; Rao, D C DC; Province, Michael A MA; Kraja, Aldi T AT

Publication Date: 2010-06

Variant appearance in text: rs12286037

PubMed Link: 20406164

Variant Present in the following documents:

• Main text

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A polygenic basis for four classical Fredrickson hyperlipoproteinemia phenotypes that are characterized by hypertriglyceridemia.

Human Molecular Genetics

Hegele, Robert A RA; Ban, Matthew R MR; Hsueh, Neil N; Kennedy, Brooke A BA; Cao, Henian H; Zou, Guang Yong GY; Anand, Sonia S; Yusuf, Salim S; Huff, Murray W MW; Wang, Jian J

Publication Date: 2009-11-01

Variant appearance in text: rs12286037

PubMed Link: 19656773

Variant Present in the following documents:

• Main text
• ddp361_1.pdf
• ddp361.pdf

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Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.

Nature Genetics

Sabatti, Chiara C; Service, Susan K SK; Hartikainen, Anna-Liisa AL; Pouta, Anneli A; Ripatti, Samuli S; Brodsky, Jae J; Jones, Chris G CG; Zaitlen, Noah A NA; Varilo, Teppo T; Kaakinen, Marika M; Sovio, Ulla U; Ruokonen, Aimo A; Laitinen, Jaana J; Jakkula, Eveliina E; Coin, Lachlan L; Hoggart, Clive C; Collins, Andrew A; Turunen, Hannu H; Gabriel, Stacey S; Elliot, Paul P; McCarthy, Mark I MI; Daly, Mark J MJ; Järvelin, Marjo-Riitta MR; Freimer, Nelson B NB; Peltonen, Leena L

Publication Date: 2009-01

Variant appearance in text: rs12286037

PubMed Link: 19060910

Variant Present in the following documents:

• Main text

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Metabolic and cardiovascular traits: an abundance of recently identified common genetic variants.

Human Molecular Genetics

Mohlke, Karen L KL; Boehnke, Michael M; Abecasis, Gonçalo R GR

Publication Date: 2008-10-15

Variant appearance in text: rs12286037

PubMed Link: 18852197

Variant Present in the following documents:

• Main text

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Newly identified loci that influence lipid concentrations and risk of coronary artery disease.

Nature Genetics

Willer, Cristen J CJ; Sanna, Serena S; Jackson, Anne U AU; Scuteri, Angelo A; Bonnycastle, Lori L LL; Clarke, Robert R; Heath, Simon C SC; Timpson, Nicholas J NJ; Najjar, Samer S SS; Stringham, Heather M HM; Strait, James J; Duren, William L WL; Maschio, Andrea A; Busonero, Fabio F; Mulas, Antonella A; Albai, Giuseppe G; Swift, Amy J AJ; Morken, Mario A MA; Narisu, Narisu N; Bennett, Derrick D; Parish, Sarah S; Shen, Haiqing H; Galan, Pilar P; Meneton, Pierre P; Hercberg, Serge S; Zelenika, Diana D; Chen, Wei-Min WM; Li, Yun Y; Scott, Laura J LJ; Scheet, Paul A PA; Sundvall, Jouko J; Watanabe, Richard M RM; Nagaraja, Ramaiah R; Ebrahim, Shah S; Lawlor, Debbie A DA; Ben-Shlomo, Yoav Y; Davey-Smith, George G; Shuldiner, Alan R AR; Collins, Rory R; Bergman, Richard N RN; Uda, Manuela M; Tuomilehto, Jaakko J; Cao, Antonio A; Collins, Francis S FS; Lakatta, Edward E; Lathrop, G Mark GM; Boehnke, Michael M; Schlessinger, David D; Mohlke, Karen L KL; Abecasis, Gonçalo R GR

Publication Date: 2008-02

Variant appearance in text: rs12286037

PubMed Link: 18193043

Variant Present in the following documents:

• Main text

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