A KCNQ1 mutation contributes to the concealed type 1 long QT phenotype by limiting the Kv7.1 channel conformational changes associated with protein kinase A phosphorylation.
Heart Rhythm
Bartos, Daniel C DC; Giudicessi, John R JR; Tester, David J DJ; Ackerman, Michael J MJ; Ohno, Seiko S; Horie, Minoru M; Gollob, Michael H MH; Burgess, Don E DE; Delisle, Brian P BP
IKs response to protein kinase A-dependent KCNQ1 phosphorylation requires direct interaction with microtubules.
Cardiovascular Research
Nicolas, Céline S CS; Park, Kyu-Ho KH; El Harchi, Aziza A; Camonis, Jacques J; Kass, Robert S RS; Escande, Denis D; Mérot, Jean J; Loussouarn, Gildas G; Le Bouffant, Françoise F; Baró, Isabelle I