Publications:

Two small-molecule activators share similar effector sites in the KCNQ1 channel pore but have distinct effects on voltage sensor movements.

Frontiers In Physiology

Chen, Lei L; Peng, Gary G; Comollo, Thomas W TW; Zou, Xinle X; Sampson, Kevin J KJ; Larsson, H Peter HP; Kass, Robert S RS

Publication Date: 2022

Variant appearance in text: KCNQ1: I337V

PubMed Link: 35957984

Variant Present in the following documents:

• Main text
• fphys-13-903050.pdf

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The membrane protein KCNQ1 potassium ion channel: Functional diversity and current structural insights.

Biochimica Et Biophysica Acta. Biomembranes

Dixit, Gunjan G; Dabney-Smith, Carole C; Lorigan, Gary A GA

Publication Date: 2020-05-01

Variant appearance in text: KCNQ1: I337V

PubMed Link: 31825788

Variant Present in the following documents:

• Main text

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Association between potassium channel SNPs and essential hypertension in Xinjiang Kazak Chinese patients.

Experimental And Therapeutic Medicine

Han, Yuan-Yuan YY; Wang, Li-Jie LJ; Zhang, Liang L; Zhang, Wen-Wen WW; Ma, Ke-Tao KT; Li, Li L; Si, Jun-Qiang JQ

Publication Date: 2017-09

Variant appearance in text: KCNQ1: I337V

PubMed Link: 28962116

Variant Present in the following documents:

• etm-14-03-1999.pdf

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KCNE1 induces fenestration in the Kv7.1/KCNE1 channel complex that allows for highly specific pharmacological targeting.

Nature Communications

Wrobel, Eva E; Rothenberg, Ina I; Krisp, Christoph C; Hundt, Franziska F; Fraenzel, Benjamin B; Eckey, Karina K; Linders, Joannes T M JT; Gallacher, David J DJ; Towart, Rob R; Pott, Lutz L; Pusch, Michael M; Yang, Tao T; Roden, Dan M DM; Kurata, Harley T HT; Schulze-Bahr, Eric E; Strutz-Seebohm, Nathalie N; Wolters, Dirk D; Seebohm, Guiscard G

Publication Date: 2016-10-12

Variant appearance in text: Kv7.1: I337V

PubMed Link: 27731317

Variant Present in the following documents:

• Main text
• ncomms12795.pdf

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Molecular impact of MinK on the enantiospecific block of I(Ks) by chromanols.

British Journal Of Pharmacology

Lerche, C C; Seebohm, G G; Wagner, C I CI; Scherer, C R CR; Dehmelt, L L; Abitbol, I I; Gerlach, U U; Brendel, J J; Attali, B B; Busch, A E AE

Publication Date: 2000-12

Variant appearance in text: KCNQ1: I337V

PubMed Link: 11139424

Variant Present in the following documents:

• Main text

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