Type 2 Diabetes-Related Variants Influence the Risk of Developing Prostate Cancer: A Population-Based Case-Control Study and Meta-Analysis.
Cancers
Sánchez-Maldonado, José Manuel JM; Collado, Ricardo R; Cabrera-Serrano, Antonio José AJ; Ter Horst, Rob R; Gálvez-Montosa, Fernando F; Robles-Fernández, Inmaculada I; Arenas-Rodríguez, Verónica V; Cano-Gutiérrez, Blanca B; Bakker, Olivier O; Bravo-Fernández, María Inmaculada MI; García-Verdejo, Francisco José FJ; López, José Antonio López JAL; Olivares-Ruiz, Jesús J; López-Nevot, Miguel Ángel MÁ; Fernández-Puerta, Laura L; Cózar-Olmo, José Manuel JM; Li, Yang Y; Netea, Mihai G MG; Jurado, Manuel M; Lorente, Jose Antonio JA; Sánchez-Rovira, Pedro P; Álvarez-Cubero, María Jesús MJ; Sainz, Juan J
Celebrities in the heart, strangers in the pancreatic beta cell: Voltage-gated potassium channels Kv 7.1 and Kv 11.1 bridge long QT syndrome with hyperinsulinaemia as well as type 2 diabetes.
Acta Physiologica (Oxford, England)
Lubberding, Anniek F AF; Juhl, Christian R CR; Skovhøj, Emil Z EZ; Kanters, Jørgen K JK; Mandrup-Poulsen, Thomas T; Torekov, Signe S SS
Polygenic risk scores predict diabetes complications and their response to intensive blood pressure and glucose control.
Diabetologia
Tremblay, Johanne J; Haloui, Mounsif M; Attaoua, Redha R; Tahir, Ramzan R; Hishmih, Camil C; Harvey, François F; Marois-Blanchet, François-Christophe FC; Long, Carole C; Simon, Paul P; Santucci, Lara L; Hizel, Candan C; Chalmers, John J; Marre, Michel M; Harrap, Stephen S; Cífková, Renata R; Krajčoviechová, Alena A; Matthews, David R DR; Williams, Bryan B; Poulter, Neil N; Zoungas, Sophia S; Colagiuri, Stephen S; Mancia, Giuseppe G; Grobbee, Diederick E DE; Rodgers, Anthony A; Liu, Liusheng L; Agbessi, Mawussé M; Bruat, Vanessa V; Favé, Marie-Julie MJ; Harwood, Michelle P MP; Awadalla, Philip P; Woodward, Mark M; Hussin, Julie G JG; Hamet, Pavel P
The role of CTCF in the organization of the centromeric 11p15 imprinted domain interactome.
Nucleic Acids Research
Naveh, Natali S Sobel NSS; Deegan, Daniel F DF; Huhn, Jacklyn J; Traxler, Emily E; Lan, Yemin Y; Weksberg, Rosanna R; Ganguly, Arupa A; Engel, Nora N; Kalish, Jennifer M JM
All thresholds of maternal hyperglycaemia from the WHO 2013 criteria for gestational diabetes identify women with a higher genetic risk for type 2 diabetes.
Wellcome Open Research
Hughes, Alice E AE; Hayes, M Geoffrey MG; Egan, Aoife M AM; Patel, Kashyap A KA; Scholtens, Denise M DM; Lowe, Lynn P LP; Lowe, William L WL; Dunne, Fidelma P FP; Hattersley, Andrew T AT; Freathy, Rachel M RM
Genetic factors and risk of type 2 diabetes among women with a history of gestational diabetes: findings from two independent populations.
Bmj Open Diabetes Research & Care
Li, Mengying M; Rahman, Mohammad L ML; Wu, Jing J; Ding, Ming M; Chavarro, Jorge E JE; Lin, Yuan Y; Ley, Sylvia H SH; Bao, Wei W; Grunnet, Louise G LG; Hinkle, Stefanie N SN; Thuesen, Anne Cathrine B ACB; Yeung, Edwina E; Gore-Langton, Robert E RE; Sherman, Seth S; Hjort, Line L; Kampmann, Freja Bach FB; Bjerregaard, Anne Ahrendt AA; Damm, Peter P; Tekola-Ayele, Fasil F; Liu, Aiyi A; Mills, James L JL; Vaag, Allan A; Olsen, Sjurdur F SF; Hu, Frank B FB; Zhang, Cuilin C
A diabetes-associated genetic variant is associated with diastolic dysfunction and cardiovascular disease.
Esc Heart Failure
Molvin, John J; Jujic, Amra A; Nilsson, Peter M PM; Leosdottir, Margret M; Lindblad, Ulf U; Daka, Bledar B; Bennet, Louise L; Råstam, Lennart L; Lyssenko, Valeriya V; Magnusson, Martin M
Blood-based analysis of type-2 diabetes mellitus susceptibility genes identifies specific transcript variants with deregulated expression and association with disease risk.
Scientific Reports
Christodoulou, Maria-Ioanna MI; Avgeris, Margaritis M; Kokkinopoulou, Ioanna I; Maratou, Eirini E; Mitrou, Panayota P; Kontos, Christos K CK; Pappas, Efthimios E; Boutati, Eleni E; Scorilas, Andreas A; Fragoulis, Emmanuel G EG
Differential methylation of the type 2 diabetes susceptibility locus KCNQ1 is associated with insulin sensitivity and is predicted by CpG site specific genetic variation.
Diabetes Research And Clinical Practice
Shah, Ushma J UJ; Xie, Weijia W; Flyvbjerg, Allan A; Nolan, John J JJ; Højlund, Kurt K; Walker, Mark M; Relton, Caroline L CL; Elliott, Hannah R HR; ,
Genome-wide survey of parent-of-origin effects on DNA methylation identifies candidate imprinted loci in humans.
Human Molecular Genetics
Cuellar Partida, Gabriel G; Laurin, Charles C; Ring, Susan M SM; Gaunt, Tom R TR; McRae, Allan F AF; Visscher, Peter M PM; Montgomery, Grant W GW; Martin, Nicholas G NG; Hemani, Gibran G; Suderman, Matthew M; Relton, Caroline L CL; Davey Smith, George G; Evans, David M DM
Impact of body weight, low energy diet and gastric bypass on drug bioavailability, cardiovascular risk factors and metabolic biomarkers: protocol for an open, non-randomised, three-armed single centre study (COCKTAIL).
Bmj Open
Hjelmesæth, Jøran J; Åsberg, Anders A; Andersson, Shalini S; Sandbu, Rune R; Robertsen, Ida I; Johnson, Line Kristin LK; Angeles, Philip Carlo PC; Hertel, Jens Kristoffer JK; Skovlund, Eva E; Heijer, Maria M; Ek, Anna-Lena AL; Krogstad, Veronica V; Karlsen, Tor-Ivar TI; Christensen, Hege H; Andersson, Tommy B TB; Karlsson, Cecilia C
Influence of genetic ancestry and socioeconomic status on type 2 diabetes in the diverse Colombian populations of Chocó and Antioquia.
Scientific Reports
Chande, Aroon T AT; Rowell, Jessica J; Rishishwar, Lavanya L; Conley, Andrew B AB; Norris, Emily T ET; Valderrama-Aguirre, Augusto A; Medina-Rivas, Miguel A MA; Jordan, I King IK
CDKAL1 rs7756992 is associated with diabetic retinopathy in a Chinese population with type 2 diabetes.
Scientific Reports
Peng, Danfeng D; Wang, Jie J; Zhang, Rong R; Jiang, Feng F; Tam, Claudia H T CHT; Jiang, Guozhi G; Wang, Tao T; Chen, Miao M; Yan, Jing J; Wang, Shiyun S; Yan, Dandan D; He, Zhen Z; Ma, Ronald C W RCW; Bao, Yuqian Y; Hu, Cheng C; Jia, Weiping W
Introduction of the DiaGene study: clinical characteristics, pathophysiology and determinants of vascular complications of type 2 diabetes.
Diabetology & Metabolic Syndrome
van Herpt, Thijs T W TTW; Lemmers, Roosmarijn F H RFH; van Hoek, Mandy M; Langendonk, Janneke G JG; Erdtsieck, Ronald J RJ; Bravenboer, Bert B; Lucas, Annelies A; Mulder, Monique T MT; Haak, Harm R HR; Lieverse, Aloysius G AG; Sijbrands, Eric J G EJG
Influence of depression on genetic predisposition to type 2 diabetes in a multiethnic longitudinal study.
Scientific Reports
Garasia, Sophiya S; Samaan, Zainab Z; Gerstein, Hertzel C HC; Engert, James C JC; Mohan, Viswanathan V; Diaz, Rafael R; Anand, Sonia S SS; Meyre, David D
Lifestyle Advice Combined with Personalized Estimates of Genetic or Phenotypic Risk of Type 2 Diabetes, and Objectively Measured Physical Activity: A Randomized Controlled Trial.
Plos Medicine
Godino, Job G JG; van Sluijs, Esther M F EM; Marteau, Theresa M TM; Sutton, Stephen S; Sharp, Stephen J SJ; Griffin, Simon J SJ
Several type 2 diabetes-associated variants in genes annotated to WNT signaling interact with dietary fiber in relation to incidence of type 2 diabetes.
Genes & Nutrition
Hindy, George G; Mollet, Inês G IG; Rukh, Gull G; Ericson, Ulrika U; Orho-Melander, Marju M
A common variant within the HNF1B gene is associated with overall survival of multiple myeloma patients: results from the IMMEnSE consortium and meta-analysis.
Oncotarget
Ríos-Tamayo, Rafael R; Lupiañez, Carmen Belén CB; Campa, Daniele D; Hielscher, Thomas T; Weinhold, Niels N; Martínez-López, Joaquin J; Jerez, Andrés A; Landi, Stefano S; Jamroziak, Krzysztof K; Dumontet, Charles C; Wątek, Marzena M; Lesueur, Fabienne F; Reis, Rui Manuel RM; Marques, Herlander H; Jurczyszyn, Artur A; Vogel, Ulla U; Buda, Gabriele G; García-Sanz, Ramón R; Orciuolo, Enrico E; Petrini, Mario M; Vangsted, Annette J AJ; Gemignani, Federica F; Försti, Asta A; Goldschmidt, Hartmut H; Hemminki, Kari K; Canzian, Federico F; Jurado, Manuel M; Sainz, Juan J
Transancestral fine-mapping of four type 2 diabetes susceptibility loci highlights potential causal regulatory mechanisms.
Human Molecular Genetics
Horikoshi, Momoko M; Pasquali, Lorenzo L; Wiltshire, Steven S; Huyghe, Jeroen R JR; Mahajan, Anubha A; Asimit, Jennifer L JL; Ferreira, Teresa T; Locke, Adam E AE; Robertson, Neil R NR; Wang, Xu X; Sim, Xueling X; Fujita, Hayato H; Hara, Kazuo K; Young, Robin R; Zhang, Weihua W; Choi, Sungkyoung S; Chen, Han H; Kaur, Ismeet I; Takeuchi, Fumihiko F; Fontanillas, Pierre P; Thuillier, Dorothée D; Yengo, Loic L; Below, Jennifer E JE; Tam, Claudia H T CH; Wu, Ying Y; Abecasis, Gonçalo G; Altshuler, David D; Bell, Graeme I GI; Blangero, John J; Burtt, Noél P NP; Duggirala, Ravindranath R; Florez, Jose C JC; Hanis, Craig L CL; Seielstad, Mark M; Atzmon, Gil G; Chan, Juliana C N JC; Ma, Ronald C W RC; Froguel, Philippe P; Wilson, James G JG; Bharadwaj, Dwaipayan D; Dupuis, Josee J; Meigs, James B JB; Cho, Yoon Shin YS; Park, Taesung T; Kooner, Jaspal S JS; Chambers, John C JC; Saleheen, Danish D; Kadowaki, Takashi T; Tai, E Shyong ES; Mohlke, Karen L KL; Cox, Nancy J NJ; Ferrer, Jorge J; Zeggini, Eleftheria E; Kato, Norihiro N; Teo, Yik Ying YY; Boehnke, Michael M; McCarthy, Mark I MI; Morris, Andrew P AP; ,
The Association of Type 2 Diabetes Loci Identified in Genome-Wide Association Studies with Metabolic Syndrome and Its Components in a Chinese Population with Type 2 Diabetes.
Plos One
Kong, Xiaomu X; Zhang, Xuelian X; Xing, Xiaoyan X; Zhang, Bo B; Hong, Jing J; Yang, Wenying W
Utilizing Genetic Predisposition Score in Predicting Risk of Type 2 Diabetes Mellitus Incidence: A Community-based Cohort Study on Middle-aged Koreans.
Journal Of Korean Medical Science
Park, Hye Yin HY; Choi, Hyung Jin HJ; Hong, Yun-Chul YC
Role of Established Type 2 Diabetes-Susceptibility Genetic Variants in a High Prevalence American Indian Population.
Diabetes
Hanson, Robert L RL; Rong, Rong R; Kobes, Sayuko S; Muller, Yunhua Li YL; Weil, E Jennifer EJ; Curtis, Jeffrey M JM; Nelson, Robert G RG; Baier, Leslie J LJ