Publications:

---

Predicting the effects of rare genetic variants on oncogenic signaling pathways: A computational analysis of HRAS protein function.

Frontiers In Chemistry

Ali, Sadaqat S; Ali, Usman U; Qamar, Adeem A; Zafar, Imran I; Yaqoob, Muhammad M; Ain, Qurat Ul QU; Rashid, Summya S; Sharma, Rohit R; Nafidi, Hiba-Allah HA; Bin Jardan, Yousef A YA; Bourhia, Mohammed M

Publication Date: 2023

Variant appearance in text: HRAS: G60V; rs730880460

PubMed Link: 37153521

Variant Present in the following documents:

• Main text
• fchem-11-1173624.pdf

View BVdb publication page

---

Somatic mutation distribution across tumour cohorts provides a signal for positive selection in cancer.

Nature Communications

Boström, Martin M; Larsson, Erik E

Publication Date: 2022-11-17

Variant appearance in text: HRAS: G60V

PubMed Link: 36396655

Variant Present in the following documents:

• 41467_2022_34746_MOESM10_ESM.xlsx, sheet 1

View BVdb publication page

---

Predicting Deleterious Non-Synonymous Single Nucleotide Polymorphisms (nsSNPs) of HRAS Gene and In Silico Evaluation of Their Structural and Functional Consequences towards Diagnosis and Prognosis of Cancer.

Biology

Chai, Chuan-Yu CY; Maran, Sathiya S; Thew, Hin-Yee HY; Tan, Yong-Chiang YC; Rahman, Nik Mohd Afizan Nik Abd NMANA; Cheng, Wan-Hee WH; Lai, Kok-Song KS; Loh, Jiun-Yan JY; Yap, Wai-Sum WS

Publication Date: 2022-11-02

Variant appearance in text: HRAS: G60V; rs730880460

PubMed Link: 36358305

Variant Present in the following documents:

• Main text
• biology-11-01604.pdf

View BVdb publication page

---

A novel HRAS c.466C>T p.(Phe156Leu) variant in two patients with attenuated features of Costello syndrome.

European Journal Of Human Genetics : Ejhg

Lindsey-Temple, Suzanna S; Edwards, Matt M; Rickassel, Verena V; Nauth, Theresa T; Rosenberger, Georg G

Publication Date: 2022-09

Variant appearance in text: HRAS: 179G>T; Gly60Val

PubMed Link: 35764878

Variant Present in the following documents:

• 41431_2022_1139_MOESM1_ESM.pdf
• 41431_2022_Article_1139.pdf

View BVdb publication page

---

Multidisciplinary Management of Costello Syndrome: Current Perspectives.

Journal Of Multidisciplinary Healthcare

Leoni, Chiara C; Viscogliosi, Germana G; Tartaglia, Marco M; Aoki, Yoko Y; Zampino, Giuseppe G

Publication Date: 2022

Variant appearance in text: HRAS: Gly60Val

PubMed Link: 35677617

Variant Present in the following documents:

• Main text
• jmdh-15-1277.pdf

View BVdb publication page

---

Are transient protein-protein interactions more dispensable?

Plos Computational Biology

Ghadie, Mohamed Ali MA; Xia, Yu Y

Publication Date: 2022-04

Variant appearance in text: HRAS: 179G>T; Gly60Val

PubMed Link: 35404956

Variant Present in the following documents:

• pcbi.1010013.s002.xlsx, sheet 4

View BVdb publication page

---

Improvement of Neoantigen Identification Through Convolution Neural Network.

Frontiers In Immunology

Hao, Qing Q; Wei, Ping P; Shu, Yang Y; Zhang, Yi-Guan YG; Xu, Heng H; Zhao, Jun-Ning JN

Publication Date: 2021

Variant appearance in text: HRAS: G60V

PubMed Link: 34113354

Variant Present in the following documents:

• Table_1.xlsx, sheet 30

View BVdb publication page

---

Spatially interacting phosphorylation sites and mutations in cancer.

Nature Communications

Huang, Kuan-Lin KL; Scott, Adam D AD; Zhou, Daniel Cui DC; Wang, Liang-Bo LB; Weerasinghe, Amila A; Elmas, Abdulkadir A; Liu, Ruiyang R; Wu, Yige Y; Wendl, Michael C MC; Wyczalkowski, Matthew A MA; Baral, Jessika J; Sengupta, Sohini S; Lai, Chin-Wen CW; Ruggles, Kelly K; Payne, Samuel H SH; Raphael, Benjamin B; Fenyö, David D; Chen, Ken K; Mills, Gordon G; Ding, Li L

Publication Date: 2021-04-19

Variant appearance in text: HRAS: G60V

PubMed Link: 33875650

Variant Present in the following documents:

• 41467_2021_22481_MOESM4_ESM.xlsx, sheet 1
• 41467_2021_22481_MOESM4_ESM.xlsx, sheet 6

View BVdb publication page

---

Identification of pathogenic missense mutations using protein stability predictors.

Scientific Reports

Gerasimavicius, Lukas L; Liu, Xin X; Marsh, Joseph A JA

Publication Date: 2020-09-21

Variant appearance in text: HRAS: G60V

PubMed Link: 32958805

Variant Present in the following documents:

• 41598_2020_72404_MOESM2_ESM.xlsx, sheet 2

View BVdb publication page

---

Costello syndrome: Clinical phenotype, genotype, and management guidelines.

American Journal Of Medical Genetics. Part A

Gripp, Karen W KW; Morse, Lindsey A LA; Axelrad, Marni M; Chatfield, Kathryn C KC; Chidekel, Aaron A; Dobyns, William W; Doyle, Daniel D; Kerr, Bronwyn B; Lin, Angela E AE; Schwartz, David D DD; Sibbles, Barbara J BJ; Siegel, Dawn D; Shankar, Suma P SP; Stevenson, David A DA; Thacker, Mihir M MM; Weaver, K Nicole KN; White, Sue M SM; Rauen, Katherine A KA

Publication Date: 2019-09

Variant appearance in text: HRAS: G60V

PubMed Link: 31222966

Variant Present in the following documents:

• Main text

View BVdb publication page

---