Publications:

Characterization of the membrane interactions of phospholipase Cγ reveals key features of the active enzyme.

Science Advances

Le Huray, Kyle I P KIP; Bunney, Tom D TD; Pinotsis, Nikos N; Kalli, Antreas C AC; Katan, Matilda M

Publication Date: 2022-06-24

Variant appearance in text: PC: D1165H

PubMed Link: 35749497

Variant Present in the following documents:

• Main text
• sciadv.abp9688.pdf

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Dynamics of allosteric regulation of the phospholipase C-γ isozymes upon recruitment to membranes.

Elife

Siraliev-Perez, Edhriz E; Stariha, Jordan T B JTB; Hoffmann, Reece M RM; Temple, Brenda R S BRS; Zhang, Qisheng Q; Hajicek, Nicole N; Jenkins, Meredith L ML; Burke, John E JE; Sondek, John J

Publication Date: 2022-06-16

Variant appearance in text: PC: D1165H

PubMed Link: 35708309

Variant Present in the following documents:

• elife-77809.pdf

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Structural insights and activating mutations in diverse pathologies define mechanisms of deregulation for phospholipase C gamma enzymes.

Ebiomedicine

Liu, Yang Y; Bunney, Tom D TD; Khosa, Sakshi S; Macé, Kévin K; Beckenbauer, Katharina K; Askwith, Trevor T; Maslen, Sarah S; Stubbs, Christopher C; de Oliveira, Taiana M TM; Sader, Kasim K; Skehel, Mark M; Gavin, Anne-Claude AC; Phillips, Christopher C; Katan, Matilda M

Publication Date: 2020-01

Variant appearance in text: PC: D1165H

PubMed Link: 31918402

Variant Present in the following documents:

• Main text
• main.pdf

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