Publications:

Therapeutic Strategies for Spinocerebellar Ataxia Type 1.

Biomolecules

Kerkhof, Laurie M C LMC; van de Warrenburg, Bart P C BPC; van Roon-Mom, Willeke M C WMC; Buijsen, Ronald A M RAM

Publication Date: 2023-05-02

Variant appearance in text: PC: S776A

PubMed Link: 37238658

Variant Present in the following documents:

• Main text
• biomolecules-13-00788.pdf

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Moving Towards Therapy in SCA1: Insights from Molecular Mechanisms, Identification of Novel Targets, and Planning for Human Trials.

Neurotherapeutics : The Journal Of The American Society For Experimental Neurotherapeutics

Srinivasan, Sharan R SR; Shakkottai, Vikram G VG

Publication Date: 2019-10

Variant appearance in text: PC: S776A

PubMed Link: 31338702

Variant Present in the following documents:

• Main text

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Reduction of protein kinase A-mediated phosphorylation of ATXN1-S776 in Purkinje cells delays onset of Ataxia in a SCA1 mouse model.

Neurobiology Of Disease

Pérez Ortiz, Judit M JM; Mollema, Nissa N; Toker, Nicholas N; Adamski, Carolyn J CJ; O'Callaghan, Brennon B; Duvick, Lisa L; Friedrich, Jillian J; Walters, Michael A MA; Strasser, Jessica J; Hawkinson, Jon E JE; Zoghbi, Huda Y HY; Henzler, Christine C; Orr, Harry T HT; Lagalwar, Sarita S

Publication Date: 2018-08

Variant appearance in text: PC: S776A

PubMed Link: 29758256

Variant Present in the following documents:

• Main text

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A native interactor scaffolds and stabilizes toxic ATAXIN-1 oligomers in SCA1.

Elife

Lasagna-Reeves, Cristian A CA; Rousseaux, Maxime Wc MW; Guerrero-Muñoz, Marcos J MJ; Park, Jeehye J; Jafar-Nejad, Paymaan P; Richman, Ronald R; Lu, Nan N; Sengupta, Urmi U; Litvinchuk, Alexandra A; Orr, Harry T HT; Kayed, Rakez R; Zoghbi, Huda Y HY

Publication Date: 2015-05-19

Variant appearance in text: PC: S776A

PubMed Link: 25988806

Variant Present in the following documents:

• Main text
• elife07558.pdf

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Vascular endothelial growth factor ameliorates the ataxic phenotype in a mouse model of spinocerebellar ataxia type 1.

Nature Medicine

Cvetanovic, Marija M; Patel, Jay M JM; Marti, Hugo H HH; Kini, Ameet R AR; Opal, Puneet P

Publication Date: 2011-10-16

Variant appearance in text: PC: S776A

PubMed Link: 22001907

Variant Present in the following documents:

• NIHMS320642-supplement-1.pdf

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