PC c.1615G>A ;(p.A539T)

Variant ID: 11-66620120-C-T

NM_001040716.1(PC):c.1615G>A;(p.A539T)

This variant was identified in 8 publications

View GRCh38 version.




Publications:


Evaluation of a Gene-Environment Interaction of PON1 and Low-Level Nerve Agent Exposure with Gulf War Illness: A Prevalence Case-Control Study Drawn from the U.S. Military Health Survey's National Population Sample.

Environmental Health Perspectives
Haley, Robert W RW; Kramer, Gerald G; Xiao, Junhui J; Dever, Jill A JA; Teiber, John F JF
Publication Date: 2022-05

Variant appearance in text: PC: A539T
PubMed Link: 35543525
Variant Present in the following documents:
  • ehp9009.pdf
View BVdb publication page



Coronary Heart Disease in Type 2 Diabetes Mellitus: Genetic Factors and Their Mechanisms, Gene-Gene, and Gene-Environment Interactions in the Asian Populations.

International Journal Of Environmental Research And Public Health
Zarkasi, Khairul Anwar KA; Abdul Murad, Nor Azian NA; Ahmad, Norfazilah N; Jamal, Rahman R; Abdullah, Noraidatulakma N
Publication Date: 2022-01-06

Variant appearance in text: PC: Ala539Thr
PubMed Link: 35055468
Variant Present in the following documents:
  • Main text
  • ijerph-19-00647.pdf
View BVdb publication page



Coronary Heart Disease in Type 2 Diabetes Mellitus: Genetic Factors and Their Mechanisms, Gene-Gene, and Gene-Environment Interactions in the Asian Populations.

International Journal Of Environmental Research And Public Health
Zarkasi, Khairul Anwar KA; Abdul Murad, Nor Azian NA; Ahmad, Norfazilah N; Jamal, Rahman R; Abdullah, Noraidatulakma N
Publication Date: 2022-01-06

Variant appearance in text: PC: Ala539Thr
PubMed Link: 35055468
Variant Present in the following documents:
  • Main text
  • ijerph-19-00647.pdf
View BVdb publication page



Optimizing clinical exome design and parallel gene-testing for recessive genetic conditions in preconception carrier screening: Translational research genomic data from 14,125 exomes.

Plos Genetics
Capalbo, Antonio A; Valero, Roberto Alonso RA; Jimenez-Almazan, Jorge J; Pardo, Pere Mir PM; Fabiani, Marco M; Jiménez, David D; Simon, Carlos C; Rodriguez, Julio Martin JM
Publication Date: 2019-10

Variant appearance in text: PC: 1615G>A
PubMed Link: 31589614
Variant Present in the following documents:
  • pgen.1008409.s001.xlsx, sheet 1
View BVdb publication page



Organoids as a new model for improving regenerative medicine and cancer personalized therapy in renal diseases.

Cell Death & Disease
Grassi, Ludovica L; Alfonsi, Romina R; Francescangeli, Federica F; Signore, Michele M; De Angelis, Maria Laura ML; Addario, Antonio A; Costantini, Manuela M; Flex, Elisabetta E; Ciolfi, Andrea A; Pizzi, Simone S; Bruselles, Alessandro A; Pallocca, Matteo M; Simone, Giuseppe G; Haoui, Mustapha M; Falchi, Mario M; Milella, Michele M; Sentinelli, Steno S; Di Matteo, Paola P; Stellacci, Emilia E; Gallucci, Michele M; Muto, Giovanni G; Tartaglia, Marco M; De Maria, Ruggero R; Bonci, Désirée D
Publication Date: 2019-02-27

Variant appearance in text: PC: 1615G>A
PubMed Link: 30814510
Variant Present in the following documents:
  • 41419_2019_1453_MOESM27_ESM.xlsx, sheet 2
View BVdb publication page



Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors.

Nature Communications
Schütte, Moritz M; Risch, Thomas T; Abdavi-Azar, Nilofar N; Boehnke, Karsten K; Schumacher, Dirk D; Keil, Marlen M; Yildiriman, Reha R; Jandrasits, Christine C; Borodina, Tatiana T; Amstislavskiy, Vyacheslav V; Worth, Catherine L CL; Schweiger, Caroline C; Liebs, Sandra S; Lange, Martin M; Warnatz, Hans-Jörg HJ; Butcher, Lee M LM; Barrett, James E JE; Sultan, Marc M; Wierling, Christoph C; Golob-Schwarzl, Nicole N; Lax, Sigurd S; Uranitsch, Stefan S; Becker, Michael M; Welte, Yvonne Y; Regan, Joseph Lewis JL; Silvestrov, Maxine M; Kehler, Inge I; Fusi, Alberto A; Kessler, Thomas T; Herwig, Ralf R; Landegren, Ulf U; Wienke, Dirk D; Nilsson, Mats M; Velasco, Juan A JA; Garin-Chesa, Pilar P; Reinhard, Christoph C; Beck, Stephan S; Schäfer, Reinhold R; Regenbrecht, Christian R A CR; Henderson, David D; Lange, Bodo B; Haybaeck, Johannes J; Keilholz, Ulrich U; Hoffmann, Jens J; Lehrach, Hans H; Yaspo, Marie-Laure ML
Publication Date: 2017-02-10

Variant appearance in text: PC: A539T
PubMed Link: 28186126
Variant Present in the following documents:
  • ncomms14262-s5.xlsx, sheet 2
View BVdb publication page



Gestational diabetes mellitus (GDM) decreases butyrylcholinesterase (BChE) activity and changes its relationship with lipids.

Genetics And Molecular Biology
Guimarães, Larissa O LO; de Andrade, Fabiana A FA; Bono, Gleyse F GF; Setoguchi, Thaís E TE; Brandão, Mariana B MB; Chautard-Freire-Maia, Eleidi A EA; Dos Santos, Izabella C R IC; Picheth, Geraldo G; Faria, Ana Cristina R de A AC; Réa, Rosângela R RR; Souza, Ricardo L R RL; Furtado-Alle, Lupe L
Publication Date: 2014-03

Variant appearance in text: PC: A539T
PubMed Link: 24688284
Variant Present in the following documents:
  • gmb-37-1.pdf
View BVdb publication page



GWAS of butyrylcholinesterase activity identifies four novel loci, independent effects within BCHE and secondary associations with metabolic risk factors.

Human Molecular Genetics
Benyamin, Beben B; Middelberg, Rita P RP; Lind, Penelope A PA; Valle, Anne M AM; Gordon, Scott S; Nyholt, Dale R DR; Medland, Sarah E SE; Henders, Anjali K AK; Heath, Andrew C AC; Madden, Pamela A F PA; Visscher, Peter M PM; O'Connor, Daniel T DT; Montgomery, Grant W GW; Martin, Nicholas G NG; Whitfield, John B JB
Publication Date: 2011-11-15

Variant appearance in text: PC: Ala539Thr
PubMed Link: 21862451
Variant Present in the following documents:
  • Main text
View BVdb publication page



Tetrahydrofurobenzofuran cymserine, a potent butyrylcholinesterase inhibitor and experimental Alzheimer drug candidate, enzyme kinetic analysis.

Journal Of Neural Transmission (Vienna, Austria : 1996)
Kamal, Mohammad A MA; Qu, Xianqin X; Yu, Qian-Sheng QS; Tweedie, David D; Holloway, Harold W HW; Li, Yazhou Y; Tan, Yi Y; Greig, Nigel H NH
Publication Date: 2008-06

Variant appearance in text: PC: Ala539Thr
PubMed Link: 18235987
Variant Present in the following documents:
  • Main text
View BVdb publication page