PtdIns(4,5)P2 stabilizes active states of GPCRs and enhances selectivity of G-protein coupling.
Nature
Yen, Hsin-Yung HY; Hoi, Kin Kuan KK; Liko, Idlir I; Hedger, George G; Horrell, Michael R MR; Song, Wanling W; Wu, Di D; Heine, Philipp P; Warne, Tony T; Lee, Yang Y; Carpenter, Byron B; Plückthun, Andreas A; Tate, Christopher G CG; Sansom, Mark S P MSP; Robinson, Carol V CV