Orthogonal cytokine engineering enables novel synthetic effector states escaping canonical exhaustion in tumor-rejecting CD8+ T cells.
Nature Immunology
Corria-Osorio, Jesus J; Carmona, Santiago J SJ; Stefanidis, Evangelos E; Andreatta, Massimo M; Ortiz-Miranda, Yaquelin Y; Muller, Tania T; Rota, Ioanna A IA; Crespo, Isaac I; Seijo, Bili B; Castro, Wilson W; Jimenez-Luna, Cristina C; Scarpellino, Leonardo L; Ronet, Catherine C; Spill, Aodrenn A; Lanitis, Evripidis E; Romero, Pedro P; Luther, Sanjiv A SA; Irving, Melita M; Coukos, George G
Achieving ultrahigh instantaneous power density of 10 MW/m2 by leveraging the opposite-charge-enhanced transistor-like triboelectric nanogenerator (OCT-TENG).
Nature Communications
Wu, Hao H; Wang, Steven S; Wang, Zuankai Z; Zi, Yunlong Y
SLE non-coding genetic risk variant determines the epigenetic dysfunction of an immune cell specific enhancer that controls disease-critical microRNA expression.
Nature Communications
Hou, Guojun G; Harley, Isaac T W ITW; Lu, Xiaoming X; Zhou, Tian T; Xu, Ning N; Yao, Chao C; Qin, Yuting Y; Ouyang, Ye Y; Ma, Jianyang J; Zhu, Xinyi X; Yu, Xiang X; Xu, Hong H; Dai, Dai D; Ding, Huihua H; Yin, Zhihua Z; Ye, Zhizhong Z; Deng, Jun J; Zhou, Mi M; Tang, Yuanjia Y; Namjou, Bahram B; Guo, Ya Y; Weirauch, Matthew T MT; Kottyan, Leah C LC; Harley, John B JB; Shen, Nan N
Dynein and dynactin leverage their bivalent character to form a high-affinity interaction.
Plos One
Siglin, Amanda E AE; Sun, Shangjin S; Moore, Jeffrey K JK; Tan, Sarah S; Poenie, Martin M; Lear, James D JD; Polenova, Tatyana T; Cooper, John A JA; Williams, John C JC
Hydroimidazolone modification of the conserved Arg12 in small heat shock proteins: studies on the structure and chaperone function using mutant mimics.