POLE c.4513C>T ;(p.P1505S)

Variant ID: 12-133219848-G-A

NM_006231.2(POLE):c.4513C>T;(p.P1505S)

This variant was identified in 4 publications

View GRCh38 version.




Publications:


POLE/POLD1 mutation in non-exonuclease domain matters for predicting efficacy of immune-checkpoint-inhibitor therapy.

Clinical And Translational Medicine
Chen, Yan-Xing YX; Wang, Zi-Xian ZX; Yuan, Shu-Qiang SQ; Jiang, Teng-Jia TJ; Huang, You-Sheng YS; Xu, Rui-Hua RH; Wang, Feng F; Zhao, Qi Q
Publication Date: 2021-09

Variant appearance in text: POLE: P1505S
PubMed Link: 34586735
Variant Present in the following documents:
  • CTM2-11-e524-s001.xlsx, sheet 6
  • CTM2-11-e524-s001.xlsx, sheet 2
View BVdb publication page



Clonal replacement of tumor-specific T cells following PD-1 blockade.

Nature Medicine
Yost, Kathryn E KE; Satpathy, Ansuman T AT; Wells, Daniel K DK; Qi, Yanyan Y; Wang, Chunlin C; Kageyama, Robin R; McNamara, Katherine L KL; Granja, Jeffrey M JM; Sarin, Kavita Y KY; Brown, Ryanne A RA; Gupta, Rohit K RK; Curtis, Christina C; Bucktrout, Samantha L SL; Davis, Mark M MM; Chang, Anne Lynn S ALS; Chang, Howard Y HY
Publication Date: 2019-08

Variant appearance in text: POLE: 4513C>T; P1505S
PubMed Link: 31359002
Variant Present in the following documents:
  • NIHMS1531727-supplement-2.xlsx, sheet 2
View BVdb publication page



Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Plos Computational Biology
Brown, Anna-Leigh AL; Li, Minghui M; Goncearenco, Alexander A; Panchenko, Anna R AR
Publication Date: 2019-04

Variant appearance in text: POLE: P1505S
PubMed Link: 31034466
Variant Present in the following documents:
  • pcbi.1006981.s010.xlsx, sheet 1
View BVdb publication page



Sequencing and curation strategies for identifying candidate glioblastoma treatments.

Bmc Medical Genomics
Frank, Mayu O MO; Koyama, Takahiko T; Rhrissorrakrai, Kahn K; Robine, Nicolas N; Utro, Filippo F; Emde, Anne-Katrin AK; Chen, Bo-Juen BJ; Arora, Kanika K; Shah, Minita M; Geiger, Heather H; Felice, Vanessa V; Dikoglu, Esra E; Rahman, Sadia S; Fang, Alice A; Vacic, Vladimir V; Bergmann, Ewa A EA; Vogel, Julia L Moore JLM; Reeves, Catherine C; Khaira, Depinder D; Calabro, Anthony A; Kim, Duyang D; Lamendola-Essel, Michelle F MF; Esteves, Cecilia C; Agius, Phaedra P; Stolte, Christian C; Boockvar, John J; Demopoulos, Alexis A; Placantonakis, Dimitris G DG; Golfinos, John G JG; Brennan, Cameron C; Bruce, Jeffrey J; Lassman, Andrew B AB; Canoll, Peter P; Grommes, Christian C; Daras, Mariza M; Diamond, Eli E; Omuro, Antonio A; Pentsova, Elena E; Orange, Dana E DE; Harvey, Stephen J SJ; Posner, Jerome B JB; Michelini, Vanessa V VV; Jobanputra, Vaidehi V; Zody, Michael C MC; Kelly, John J; Parida, Laxmi L; Wrzeszczynski, Kazimierz O KO; Royyuru, Ajay K AK; Darnell, Robert B RB
Publication Date: 2019-04-25

Variant appearance in text: POLE: P1505S
PubMed Link: 31023376
Variant Present in the following documents:
  • Main text
  • 12920_2019_Article_500.pdf
View BVdb publication page