Publications:

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AIMP2-DX2 provides therapeutic interface to control KRAS-driven tumorigenesis.

Nature Communications

Kim, Dae Gyu DG; Choi, Yongseok Y; Lee, Yuno Y; Lim, Semi S; Kong, Jiwon J; Song, JaeHa J; Roh, Younah Y; Harmalkar, Dipesh S DS; Lee, Kwanshik K; Goo, Ja-Il JI; Cho, Hye Young HY; Mushtaq, Ameeq Ul AU; Lee, Jihye J; Park, Song Hwa SH; Kim, Doyeun D; Min, Byung Soh BS; Lee, Kang Young KY; Jeon, Young Ho YH; Lee, Sunkyung S; Lee, Kyeong K; Kim, Sunghoon S

Publication Date: 2022-05-11

Variant appearance in text: KRAS: C185A

PubMed Link: 35546148

Variant Present in the following documents:

• 41467_2022_30149_MOESM1_ESM.pdf

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Stabilization of the RAS:PDE6D Complex Is a Novel Strategy to Inhibit RAS Signaling.

Journal Of Medicinal Chemistry

Yelland, Tamas T; Garcia, Esther E; Parry, Charles C; Kowalczyk, Dominika D; Wojnowska, Marta M; Gohlke, Andrea A; Zalar, Matja M; Cameron, Kenneth K; Goodwin, Gillian G; Yu, Qing Q; Zhu, Peng-Cheng PC; ElMaghloob, Yasmin Y; Pugliese, Angelo A; Archibald, Lewis L; Jamieson, Andrew A; Chen, Yong Xiang YX; McArthur, Duncan D; Bower, Justin J; Ismail, Shehab S

Publication Date: 2022-02-01

Variant appearance in text: KRAS: C185A

PubMed Link: 35104933

Variant Present in the following documents:

• Main text
• jm1c01265_si_001.pdf
• jm1c01265.pdf

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Stabilization of the RAS:PDE6D Complex Is a Novel Strategy to Inhibit RAS Signaling.

Journal Of Medicinal Chemistry

Yelland, Tamas T; Garcia, Esther E; Parry, Charles C; Kowalczyk, Dominika D; Wojnowska, Marta M; Gohlke, Andrea A; Zalar, Matja M; Cameron, Kenneth K; Goodwin, Gillian G; Yu, Qing Q; Zhu, Peng-Cheng PC; ElMaghloob, Yasmin Y; Pugliese, Angelo A; Archibald, Lewis L; Jamieson, Andrew A; Chen, Yong Xiang YX; McArthur, Duncan D; Bower, Justin J; Ismail, Shehab S

Publication Date: 2022-02-10

Variant appearance in text: KRAS: C185A

PubMed Link: 35104933

Variant Present in the following documents:

• Main text
• jm1c01265_si_001.pdf
• jm1c01265.pdf

View BVdb publication page

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Development of a High-throughput NanoBRET Screening Platform to Identify Modulators of the RAS/RAF Interaction.

Molecular Cancer Therapeutics

Durrant, David E DE; Smith, Emily A EA; Goncharova, Ekaterina I EI; Sharma, Nirmala N; Alexander, Patrick A PA; Stephen, Andrew G AG; Henrich, Curtis J CJ; Morrison, Deborah K DK

Publication Date: 2021-09

Variant appearance in text: KRAS: C185A

PubMed Link: 34158349

Variant Present in the following documents:

• Main text
• 1743.pdf

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Distinct Binding Preferences between Ras and Raf Family Members and the Impact on Oncogenic Ras Signaling.

Molecular Cell

Terrell, Elizabeth M EM; Durrant, David E DE; Ritt, Daniel A DA; Sealover, Nancy E NE; Sheffels, Erin E; Spencer-Smith, Russell R; Esposito, Dominic D; Zhou, Yong Y; Hancock, John F JF; Kortum, Robert L RL; Morrison, Deborah K DK

Publication Date: 2019-12-19

Variant appearance in text: K-Ras4B: C185A

PubMed Link: 31606273

Variant Present in the following documents:

• Main text

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Farnesylation or geranylgeranylation? Efficient assays for testing protein prenylation in vitro and in vivo.

Bmc Biochemistry

Benetka, Wolfgang W; Koranda, Manfred M; Maurer-Stroh, Sebastian S; Pittner, Fritz F; Eisenhaber, Frank F

Publication Date: 2006-02-28

Variant appearance in text: K-Ras4B: C185A

PubMed Link: 16507103

Variant Present in the following documents:

• Main text
• 1471-2091-7-6.pdf

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