KRAS c.547A>G ;(p.T183A)

Variant ID: 12-25362749-T-C

NM_004985.3(KRAS):c.547A>G;(p.T183A)

This variant was identified in 6 publications

View GRCh38 version.




Publications:


LATS kinases and SLUG regulate the transition to advanced stage in aggressive oral cancer cells.

Scientific Reports
Fujibayashi, Emi E; Mukai, Satomi S; Torigata, Kosuke K; Ando, Yumi Y; Uchihashi, Toshihiro T; Nozaki, Masami M; Tanaka, Susumu S; Okada, Masato M; Kogo, Mikihiko M; Nojima, Hiroshi H; Yabuta, Norikazu N
Publication Date: 2022-07-20

Variant appearance in text: KRAS: T183A
PubMed Link: 35859006
Variant Present in the following documents:
  • 41598_2022_Article_16667.pdf
View BVdb publication page



JAK3 mutations and mitochondrial apoptosis resistance in T-cell acute lymphoblastic leukemia.

Leukemia
Bodaar, Kimberly K; Yamagata, Natsuko N; Barthe, Anais A; Landrigan, Jack J; Chonghaile, Triona Ni TN; Burns, Melissa M; Stevenson, Kristen E KE; Devidas, Meenakshi M; Loh, Mignon L ML; Hunger, Stephen P SP; Wood, Brent B; Silverman, Lewis B LB; Teachey, David T DT; Meijerink, Jules P JP; Letai, Anthony A; Gutierrez, Alejandro A
Publication Date: 2022-06

Variant appearance in text: KRAS: 547A>G
PubMed Link: 35411095
Variant Present in the following documents:
  • NIHMS1792675-supplement-Supplementary_Table_2.xlsx, sheet 1
View BVdb publication page



Avicin G is a potent sphingomyelinase inhibitor and blocks oncogenic K- and H-Ras signaling.

Scientific Reports
Garrido, Christian M CM; Henkels, Karen M KM; Rehl, Kristen M KM; Liang, Hong H; Zhou, Yong Y; Gutterman, Jordan U JU; Cho, Kwang-Jin KJ
Publication Date: 2020-06-04

Variant appearance in text: K-Ras4B: T183A
PubMed Link: 32499517
Variant Present in the following documents:
  • Main text
  • 41598_2020_Article_65882.pdf
View BVdb publication page



Fanconi-BRCA pathway mutations in childhood T-cell acute lymphoblastic leukemia.

Plos One
Pouliot, Gayle P GP; Degar, James J; Hinze, Laura L; Kochupurakkal, Bose B; Vo, Chau D CD; Burns, Melissa A MA; Moreau, Lisa L; Ganesa, Chirag C; Roderick, Justine J; Peirs, Sofie S; Menten, Bjorn B; Loh, Mignon L ML; Hunger, Stephen P SP; Silverman, Lewis B LB; Harris, Marian H MH; Stevenson, Kristen E KE; Weinstock, David M DM; Weng, Andrew P AP; Van Vlierberghe, Pieter P; D'Andrea, Alan D AD; Gutierrez, Alejandro A
Publication Date: 2019

Variant appearance in text: KRAS: 547A>G
PubMed Link: 31721781
Variant Present in the following documents:
  • pone.0221288.s012.xlsx, sheet 1
View BVdb publication page



PRC2 loss induces chemoresistance by repressing apoptosis in T cell acute lymphoblastic leukemia.

The Journal Of Experimental Medicine
Ariës, Ingrid M IM; Bodaar, Kimberly K; Karim, Salmaan A SA; Chonghaile, Triona Ni TN; Hinze, Laura L; Burns, Melissa A MA; Pfirrmann, Maren M; Degar, James J; Landrigan, Jack T JT; Balbach, Sebastian S; Peirs, Sofie S; Menten, Björn B; Isenhart, Randi R; Stevenson, Kristen E KE; Neuberg, Donna S DS; Devidas, Meenakshi M; Loh, Mignon L ML; Hunger, Stephen P SP; Teachey, David T DT; Rabin, Karen R KR; Winter, Stuart S SS; Dunsmore, Kimberly P KP; Wood, Brent L BL; Silverman, Lewis B LB; Sallan, Stephen E SE; Van Vlierberghe, Pieter P; Orkin, Stuart H SH; Knoechel, Birgit B; Letai, Anthony G AG; Gutierrez, Alejandro A
Publication Date: 2018-12-03

Variant appearance in text: KRAS: 547A>G
PubMed Link: 30404791
Variant Present in the following documents:
  • JEM_20180570_TableS4.xlsx, sheet 1
View BVdb publication page



Structural basis of recognition of farnesylated and methylated KRAS4b by PDEδ.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Dharmaiah, Srisathiyanarayanan S; Bindu, Lakshman L; Tran, Timothy H TH; Gillette, William K WK; Frank, Peter H PH; Ghirlando, Rodolfo R; Nissley, Dwight V DV; Esposito, Dominic D; McCormick, Frank F; Stephen, Andrew G AG; Simanshu, Dhirendra K DK
Publication Date: 2016-11-01

Variant appearance in text: KRAS: T183A
PubMed Link: 27791178
Variant Present in the following documents:
  • Main text
View BVdb publication page