Publications:

Somatic mutation distribution across tumour cohorts provides a signal for positive selection in cancer.

Nature Communications

Boström, Martin M; Larsson, Erik E

Publication Date: 2022-11-17

Variant appearance in text: KRAS: K165Q

PubMed Link: 36396655

Variant Present in the following documents:

• 41467_2022_34746_MOESM10_ESM.xlsx, sheet 1

View BVdb publication page

Molecular and functional profiling identifies therapeutically targetable vulnerabilities in plasmablastic lymphoma.

Nature Communications

Frontzek, Fabian F; Staiger, Annette M AM; Zapukhlyak, Myroslav M; Xu, Wendan W; Bonzheim, Irina I; Borgmann, Vanessa V; Sander, Philip P; Baptista, Maria Joao MJ; Heming, Jan-Niklas JN; Berning, Philipp P; Wullenkord, Ramona R; Erdmann, Tabea T; Lutz, Mathias M; Veratti, Pia P; Ehrenfeld, Sophia S; Wienand, Kirsty K; Horn, Heike H; Goodlad, John R JR; Wilson, Matthew R MR; Anagnostopoulos, Ioannis I; Lamping, Mario M; Gonzalez-Barca, Eva E; Climent, Fina F; Salar, Antonio A; Castellvi, Josep J; Abrisqueta, Pau P; Menarguez, Javier J; Aldamiz, Teresa T; Richter, Julia J; Klapper, Wolfram W; Tzankov, Alexandar A; Dirnhofer, Stefan S; Rosenwald, Andreas A; Mate, José Luis JL; Tapia, Gustavo G; Lenz, Peter P; Miething, Cornelius C; Hartmann, Wolfgang W; Chapuy, Björn B; Fend, Falko F; Ott, German G; Navarro, José-Tomas JT; Grau, Michael M; Lenz, Georg G

Publication Date: 2021-08-31

Variant appearance in text: KRAS: 493A>C

PubMed Link: 34465776

Variant Present in the following documents:

• 41467_2021_25405_MOESM7_ESM.xlsx, sheet 2

View BVdb publication page

Discovery of potent SOS1 inhibitors that block RAS activation via disruption of the RAS-SOS1 interaction.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Hillig, Roman C RC; Sautier, Brice B; Schroeder, Jens J; Moosmayer, Dieter D; Hilpmann, André A; Stegmann, Christian M CM; Werbeck, Nicolas D ND; Briem, Hans H; Boemer, Ulf U; Weiske, Joerg J; Badock, Volker V; Mastouri, Julia J; Petersen, Kirstin K; Siemeister, Gerhard G; Kahmann, Jan D JD; Wegener, Dennis D; Böhnke, Niels N; Eis, Knut K; Graham, Keith K; Wortmann, Lars L; von Nussbaum, Franz F; Bader, Benjamin B

Publication Date: 2019-02-12

Variant appearance in text: KRAS: K165Q

PubMed Link: 30683722

Variant Present in the following documents:

• pnas.1812963116.sapp.pdf

View BVdb publication page

Computational Modeling Reveals that Signaling Lipids Modulate the Orientation of K-Ras4A at the Membrane Reflecting Protein Topology.

Structure (London, England : 1993)

Li, Zhen-Lu ZL; Buck, Matthias M

Publication Date: 2017-04-04

Variant appearance in text: K-Ras4B: K165Q

PubMed Link: 28286004

Variant Present in the following documents:

• Main text

View BVdb publication page

Comparison of the Conformations of KRAS Isoforms, K-Ras4A and K-Ras4B, Points to Similarities and Significant Differences.

The Journal Of Physical Chemistry. B

Chakrabarti, Mayukh M; Jang, Hyunbum H; Nussinov, Ruth R

Publication Date: 2016-02-04

Variant appearance in text: K-Ras4B: K165Q

PubMed Link: 26761128

Variant Present in the following documents:

• Main text

View BVdb publication page