Publications:

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Mutations in the α4-α5 allosteric lobe of RAS do not significantly impair RAS signaling or self-association.

The Journal Of Biological Chemistry

Whaby, Michael M; Wallon, Lauren L; Mazzei, Megan M; Khan, Imran I; Teng, Kai Wen KW; Koide, Shohei S; O'Bryan, John P JP

Publication Date: 2022-11-02

Variant appearance in text: KRAS: R161E

PubMed Link: 36334633

Variant Present in the following documents:

• Main text
• main.pdf

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The Ras dimer structure.

Chemical Science

Rudack, Till T; Teuber, Christian C; Scherlo, Marvin M; Güldenhaupt, Jörn J; Schartner, Jonas J; Lübben, Mathias M; Klare, Johann J; Gerwert, Klaus K; Kötting, Carsten C

Publication Date: 2021-05-04

Variant appearance in text: K-Ras4B: R161E

PubMed Link: 34194708

Variant Present in the following documents:

• Main text
• SC-012-D1SC00957E.pdf

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RAS Nanoclusters: Dynamic Signaling Platforms Amenable to Therapeutic Intervention.

Biomolecules

Van, Que N QN; Prakash, Priyanka P; Shrestha, Rebika R; Balius, Trent E TE; Turbyville, Thomas J TJ; Stephen, Andrew G AG

Publication Date: 2021-03-03

Variant appearance in text: KRAS: R161E

PubMed Link: 33802474

Variant Present in the following documents:

• Main text
• biomolecules-11-00377.pdf

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KRAS interaction with RAF1 RAS-binding domain and cysteine-rich domain provides insights into RAS-mediated RAF activation.

Nature Communications

Tran, Timothy H TH; Chan, Albert H AH; Young, Lucy C LC; Bindu, Lakshman L; Neale, Chris C; Messing, Simon S; Dharmaiah, Srisathiyanarayanan S; Taylor, Troy T; Denson, John-Paul JP; Esposito, Dominic D; Nissley, Dwight V DV; Stephen, Andrew G AG; McCormick, Frank F; Simanshu, Dhirendra K DK

Publication Date: 2021-02-19

Variant appearance in text: KRAS: R161E

PubMed Link: 33608534

Variant Present in the following documents:

• 41467_2021_21422_MOESM2_ESM.pdf

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Two Distinct Structures of Membrane-Associated Homodimers of GTP- and GDP-Bound KRAS4B Revealed by Paramagnetic Relaxation Enhancement.

Angewandte Chemie (International Ed. In English)

Lee, Ki-Young KY; Fang, Zhenhao Z; Enomoto, Masahiro M; Gasmi-Seabrook, Genevieve G; Zheng, Le L; Koide, Shohei S; Ikura, Mitsuhiko M; Marshall, Christopher B CB

Publication Date: 2020-06-26

Variant appearance in text: KRAS: R161E

PubMed Link: 32227412

Variant Present in the following documents:

• Main text

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Modeling and subtleties of K-Ras and Calmodulin interaction.

Plos Computational Biology

Garrido, Eduardo E; Lázaro, Juan J; Jaumot, Montserrat M; Agell, Neus N; Rubio-Martinez, Jaime J

Publication Date: 2018-10

Variant appearance in text: K-Ras4B: R161E

PubMed Link: 30376570

Variant Present in the following documents:

• Main text
• pcbi.1006552.pdf

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