KRAS interaction with RAF1 RAS-binding domain and cysteine-rich domain provides insights into RAS-mediated RAF activation.
Nature Communications
Tran, Timothy H TH; Chan, Albert H AH; Young, Lucy C LC; Bindu, Lakshman L; Neale, Chris C; Messing, Simon S; Dharmaiah, Srisathiyanarayanan S; Taylor, Troy T; Denson, John-Paul JP; Esposito, Dominic D; Nissley, Dwight V DV; Stephen, Andrew G AG; McCormick, Frank F; Simanshu, Dhirendra K DK
DIRAS3 (ARHI) Blocks RAS/MAPK Signaling by Binding Directly to RAS and Disrupting RAS Clusters.
Cell Reports
Sutton, Margie N MN; Lu, Zhen Z; Li, Yao-Cheng YC; Zhou, Yong Y; Huang, Tao T; Reger, Albert S AS; Hurwitz, Amy M AM; Palzkill, Timothy T; Logsdon, Craig C; Liang, Xiaowen X; Gray, Joe W JW; Nan, Xiaolin X; Hancock, John J; Wahl, Geoffrey M GM; Bast, Robert C RC