KRAS c.445A>G ;(p.R149G)

Variant ID: 12-25378553-T-C

NM_004985.3(KRAS):c.445A>G;(p.R149G)

This variant was identified in 7 publications

View GRCh38 version.




Publications:


Mutant p53 achieved Gain-of-Function by promoting tumor growth and immune escape through PHLPP2/AKT/PD-L1 pathway.

International Journal Of Biological Sciences
Liu, Nannan N; Jiang, Xinxiu X; Guo, Leiming L; Zhang, Chuchu C; Jiang, Meimei M; Sun, Zhuoran Z; Zhang, Yizheng Y; Mi, Wunan W; Li, Jiehan J; Fu, Yang Y; Wang, Feng F; Zhang, Lingling L; Zhang, Yingjie Y
Publication Date: 2022

Variant appearance in text: KRAS: R149G
PubMed Link: 35414774
Variant Present in the following documents:
  • ijbsv18p2419s1.pdf
View BVdb publication page



The Contribution of MicroRNAs to the Inflammatory and Neoplastic Characteristics of Erdheim-Chester Disease.

Cancers
Weissman, Ran R; Diamond, Eli L EL; Haroche, Julien J; Pillar, Nir N; Shapira, Guy G; Durham, Benjamin H BH; Buthorn, Justin J; Cohen, Fleur F; Ki, Michelle M; Stemer, Galia G; Ulaner, Gary A GA; Amoura, Zahir Z; Emile, Jean-François JF; Mazor, Roei D RD; Shomron, Noam N; Abdel-Wahab, Omar I OI; Shpilberg, Ofer O; Hershkovitz-Rokah, Oshrat O
Publication Date: 2020-11-03

Variant appearance in text: KRAS: R149G
PubMed Link: 33153128
Variant Present in the following documents:
  • Main text
  • cancers-12-03240.pdf
View BVdb publication page



18F-FDG PET/CT versus anatomic imaging for evaluating disease extent and clinical trial eligibility in Erdheim-Chester disease: results from 50 patients in a registry study.

European Journal Of Nuclear Medicine And Molecular Imaging
Kirchner, Julian J; Hatzoglou, Vaios V; Buthorn, Justin B JB; Bossert, Dana D; Sigler, Allison M AM; Reiner, Anne S AS; Ulaner, Gary A GA; Diamond, Eli L EL
Publication Date: 2021-04

Variant appearance in text: KRAS: R149G
PubMed Link: 33057928
Variant Present in the following documents:
  • Main text
View BVdb publication page



Neurologic and oncologic features of Erdheim-Chester disease: a 30-patient series.

Neuro-Oncology
Bhatia, Ankush A; Hatzoglou, Vaios V; Ulaner, Gary G; Rampal, Raajit R; Hyman, David M DM; Abdel-Wahab, Omar O; Durham, Benjamin H BH; Dogan, Ahmet A; Ozkaya, Neval N; Yabe, Mariko M; Petrova-Drus, Kseniya K; Panageas, Katherine S KS; Reiner, Anne A; Rosenblum, Marc M; Diamond, Eli L EL
Publication Date: 2020-07-07

Variant appearance in text: KRAS: R149G
PubMed Link: 31950179
Variant Present in the following documents:
  • Main text
View BVdb publication page



Efficacy of MEK inhibition in patients with histiocytic neoplasms.

Nature
Diamond, Eli L EL; Durham, Benjamin H BH; Ulaner, Gary A GA; Drill, Esther E; Buthorn, Justin J; Ki, Michelle M; Bitner, Lillian L; Cho, Hana H; Young, Robert J RJ; Francis, Jasmine H JH; Rampal, Raajit R; Lacouture, Mario M; Brody, Lynn A LA; Ozkaya, Neval N; Dogan, Ahmet A; Rosen, Neal N; Iasonos, Alexia A; Abdel-Wahab, Omar O; Hyman, David M DM
Publication Date: 2019-03

Variant appearance in text: KRAS: R149G
PubMed Link: 30867592
Variant Present in the following documents:
  • Main text
  • nihms-1521555.pdf
View BVdb publication page



Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Publication Date: 2018

Variant appearance in text: KRAS: R149G
PubMed Link: 29698444
Variant Present in the following documents:
  • pone.0196434.s001.xlsx, sheet 3
  • pone.0196434.s001.xlsx, sheet 1
  • pone.0196434.s001.xlsx, sheet 2
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Novel KRAS gene mutations in sporadic colorectal cancer.

Plos One
Naser, Walid M WM; Shawarby, Mohamed A MA; Al-Tamimi, Dalal M DM; Seth, Arun A; Al-Quorain, Abdulaziz A; Nemer, Areej M Al AM; Albagha, Omar M E OM
Publication Date: 2014

Variant appearance in text: KRAS: R149G
PubMed Link: 25412182
Variant Present in the following documents:
  • Main text
View BVdb publication page