KRAS c.442A>G ;(p.T148A)

Variant ID: 12-25378556-T-C

NM_004985.3(KRAS):c.442A>G;(p.T148A)

This variant was identified in 5 publications

View GRCh38 version.




Publications:


Nano pom-poms prepared exosomes enable highly specific cancer biomarker detection.

Communications Biology
He, Nan N; Thippabhotla, Sirisha S; Zhong, Cuncong C; Greenberg, Zachary Z; Xu, Liang L; Pessetto, Ziyan Z; Godwin, Andrew K AK; Zeng, Yong Y; He, Mei M
Publication Date: 2022-07-04

Variant appearance in text: KRAS: 442A>G; Thr148Ala
PubMed Link: 35787656
Variant Present in the following documents:
  • 42003_2022_3598_MOESM4_ESM.xlsx, sheet 2
View BVdb publication page



Identification of Ras-degrading small molecules that inhibit the transformation of colorectal cancer cells independent of β-catenin signaling.

Experimental & Molecular Medicine
Shin, Wookjin W; Lee, Sang-Kyu SK; Hwang, Jeong-Ha JH; Park, Jong-Chan JC; Cho, Yong-Hee YH; Ro, Eun Ji EJ; Song, Yeonhwa Y; Seo, Haeng Ran HR; Choi, Kang-Yell KY
Publication Date: 2018-06-06

Variant appearance in text: KRAS: T148A
PubMed Link: 29884842
Variant Present in the following documents:
  • Main text
  • 12276_2018_Article_102.pdf
View BVdb publication page



Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Publication Date: 2018

Variant appearance in text: KRAS: T148A
PubMed Link: 29698444
Variant Present in the following documents:
  • pone.0196434.s001.xlsx, sheet 1
  • pone.0196434.s001.xlsx, sheet 3
  • pone.0196434.s001.xlsx, sheet 2
View BVdb publication page



Induction of non-apoptotic programmed cell death by oncogenic RAS in human epithelial cells and its suppression by MYC overexpression.

Carcinogenesis
Dendo, Kasumi K; Yugawa, Takashi T; Nakahara, Tomomi T; Ohno, Shin-Ichi SI; Goshima, Naoki N; Arakawa, Hirofumi H; Kiyono, Tohru T
Publication Date: 2018-02-09

Variant appearance in text: KRAS: T148A
PubMed Link: 29106503
Variant Present in the following documents:
  • Main text
View BVdb publication page



Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Nature Communications
Kis, Olena O; Kaedbey, Rayan R; Chow, Signy S; Danesh, Arnavaz A; Dowar, Mark M; Li, Tiantian T; Li, Zhihua Z; Liu, Jessica J; Mansour, Mark M; Masih-Khan, Esther E; Zhang, Tong T; Bratman, Scott V SV; Oza, Amit M AM; Kamel-Reid, Suzanne S; Trudel, Suzanne S; Pugh, Trevor J TJ
Publication Date: 2017-05-11

Variant appearance in text: KRAS: 442A>G
PubMed Link: 28492226
Variant Present in the following documents:
  • ncomms15086-s3.xlsx, sheet 1
View BVdb publication page