KRAS c.439_441delinsGAC ;(p.K147D)

Variant ID: 12-25378557-CTT-GTC

NM_004985.3(KRAS):c.439_441delinsGAC;(p.K147D)

This variant was identified in 2 publications

View GRCh38 version.




Publications:


Mutations in the α4-α5 allosteric lobe of RAS do not significantly impair RAS signaling or self-association.

The Journal Of Biological Chemistry
Whaby, Michael M; Wallon, Lauren L; Mazzei, Megan M; Khan, Imran I; Teng, Kai Wen KW; Koide, Shohei S; O'Bryan, John P JP
Publication Date: 2022-11-02

Variant appearance in text: KRAS: K147D
PubMed Link: 36334633
Variant Present in the following documents:
  • Main text
View BVdb publication page



A structural model of a Ras-Raf signalosome.

Nature Structural & Molecular Biology
Mysore, Venkatesh P VP; Zhou, Zhi-Wei ZW; Ambrogio, Chiara C; Li, Lianbo L; Kapp, Jonas N JN; Lu, Chunya C; Wang, Qi Q; Tucker, Maxwell R MR; Okoro, Jeffrey J JJ; Nagy-Davidescu, Gabriela G; Bai, Xiaochen X; Plückthun, Andreas A; Jänne, Pasi A PA; Westover, Kenneth D KD; Shan, Yibing Y; Shaw, David E DE
Publication Date: 2021-10

Variant appearance in text: KRAS: K147D
PubMed Link: 34625747
Variant Present in the following documents:
  • Main text
View BVdb publication page