Publications:

KY1022, a small molecule destabilizing Ras via targeting the Wnt/β-catenin pathway, inhibits development of metastatic colorectal cancer.

Oncotarget

Cho, Yong-Hee YH; Cha, Pu-Hyeon PH; Kaduwal, Saluja S; Park, Jong-Chan JC; Lee, Sang-Kyu SK; Yoon, Jeong-Soo JS; Shin, Wookjin W; Kim, Hyuntae H; Ro, Eun Ji EJ; Koo, Kyung-Hwa KH; Park, Ki-Sook KS; Han, Gyoonhee G; Choi, Kang-Yell KY

Publication Date: 2016-12-06

Variant appearance in text: KRAS: K147A

PubMed Link: 27835580

Variant Present in the following documents:

• Main text
• oncotarget-07-81727.pdf

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Ubiquitination of K-Ras enhances activation and facilitates binding to select downstream effectors.

Science Signaling

Sasaki, Atsuo T AT; Carracedo, Arkaitz A; Locasale, Jason W JW; Anastasiou, Dimitrios D; Takeuchi, Koh K; Kahoud, Emily Rose ER; Haviv, Sasson S; Asara, John M JM; Pandolfi, Pier Paolo PP; Cantley, Lewis C LC

Publication Date: 2011-03-08

Variant appearance in text: K-Ras4B: K147A

PubMed Link: 21386094

Variant Present in the following documents:

• Main text

View BVdb publication page