KRAS c.439A>C ;(p.K147Q)

Variant ID: 12-25378559-T-G

NM_004985.3(KRAS):c.439A>C;(p.K147Q)

This variant was identified in 4 publications

View GRCh38 version.




Publications:


The landscape of somatic mutation in sporadic Chinese colorectal cancer.

Oncotarget
Liu, Zhe Z; Yang, Chao C; Li, Xiangchun X; Luo, Wen W; Roy, Bhaskar B; Xiong, Teng T; Zhang, Xiuqing X; Yang, Huanming H; Wang, Jian J; Ye, Zhenhao Z; Chen, Yang Y; Song, Jinghe J; Ma, Shuai S; Zhou, Yong Y; Yang, Min M; Fang, Xiaodong X; Du, Jie J
Publication Date: 2018-06-08

Variant appearance in text: KRAS: 439A>C
PubMed Link: 29937994
Variant Present in the following documents:
  • oncotarget-09-27412-s004.xlsx, sheet 1
View BVdb publication page



Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors.

Nature Communications
Schütte, Moritz M; Risch, Thomas T; Abdavi-Azar, Nilofar N; Boehnke, Karsten K; Schumacher, Dirk D; Keil, Marlen M; Yildiriman, Reha R; Jandrasits, Christine C; Borodina, Tatiana T; Amstislavskiy, Vyacheslav V; Worth, Catherine L CL; Schweiger, Caroline C; Liebs, Sandra S; Lange, Martin M; Warnatz, Hans-Jörg HJ; Butcher, Lee M LM; Barrett, James E JE; Sultan, Marc M; Wierling, Christoph C; Golob-Schwarzl, Nicole N; Lax, Sigurd S; Uranitsch, Stefan S; Becker, Michael M; Welte, Yvonne Y; Regan, Joseph Lewis JL; Silvestrov, Maxine M; Kehler, Inge I; Fusi, Alberto A; Kessler, Thomas T; Herwig, Ralf R; Landegren, Ulf U; Wienke, Dirk D; Nilsson, Mats M; Velasco, Juan A JA; Garin-Chesa, Pilar P; Reinhard, Christoph C; Beck, Stephan S; Schäfer, Reinhold R; Regenbrecht, Christian R A CR; Henderson, David D; Lange, Bodo B; Haybaeck, Johannes J; Keilholz, Ulrich U; Hoffmann, Jens J; Lehrach, Hans H; Yaspo, Marie-Laure ML
Publication Date: 2017-02-10

Variant appearance in text: KRAS: K147Q
PubMed Link: 28186126
Variant Present in the following documents:
  • ncomms14262-s5.xlsx, sheet 2
View BVdb publication page



SIRT2 deletion enhances KRAS-induced tumorigenesis in vivo by regulating K147 acetylation status.

Oncotarget
Song, Ha Yong HY; Biancucci, Marco M; Kang, Hong-Jun HJ; O'Callaghan, Carol C; Park, Seong-Hoon SH; Principe, Daniel R DR; Jiang, Haiyan H; Yan, Yufan Y; Satchell, Karla Fullner KF; Raparia, Kirtee K; Gius, David D; Vassilopoulos, Athanassios A
Publication Date: 2016-12-06

Variant appearance in text: KRAS: K147Q
PubMed Link: 27637077
Variant Present in the following documents:
  • Main text
  • oncotarget-07-80336.pdf
  • oncotarget-07-80336-s001.pdf
View BVdb publication page



The American Pancreatic Association/Hirshberg Foundation Symposium celebrating the 10th anniversary of the Seed Grant program.

Pancreas
Hirshberg, Agi A; Carney, Jennifer B JB; Go, Vay Liang W VL
Publication Date: 2014-03

Variant appearance in text: KRAS: K147Q
PubMed Link: 24518493
Variant Present in the following documents:
  • mpa-43-153.pdf
View BVdb publication page