Publications:

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Analysis of Circulating Tumor DNA in Synchronous Metastatic Colorectal Cancer at Diagnosis Predicts Overall Patient Survival.

International Journal Of Molecular Sciences

Sayagués, José María JM; Montero, Juan Carlos JC; Jiménez-Pérez, Andrea A; Del Carmen, Sofía S; Rodríguez, Marta M; Vidal Tocino, Rosario R; Montero, Enrique E; Sanz, Julia J; Abad, Mar M

Publication Date: 2023-05-08

Variant appearance in text: KRAS: A146P

PubMed Link: 37176143

Variant Present in the following documents:

• ijms-24-08438.pdf

View BVdb publication page

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Pretreatment Plasma Circulating Tumor DNA RAS/BRAF Mutational Status in Refractory Metastatic Colorectal Cancer Patients Who Are Candidates for Anti-EGFR Rechallenge Therapy: A Pooled Analysis of the CAVE and VELO Clinical Trials.

Cancers

Ciardiello, Davide D; Napolitano, Stefania S; Famiglietti, Vincenzo V; Esposito, Lucia L; De Falco, Vincenzo V; Di Liello, Alessandra A; Avallone, Antonio A; Maiello, Evaristo E; Pietrantonio, Filippo F; Cremolini, Chiara C; Zampino, Maria Giulia MG; Fazio, Nicola N; Troiani, Teresa T; Martinelli, Erika E; Ciardiello, Fortunato F; Martini, Giulia G

Publication Date: 2023-04-01

Variant appearance in text: KRAS: A146P

PubMed Link: 37046778

Variant Present in the following documents:

• cancers-15-02117.pdf

View BVdb publication page

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Direct GDP-KRASG12C inhibitors and mechanisms of resistance: the tip of the iceberg.

Therapeutic Advances In Medical Oncology

Rosen, Joshua C JC; Sacher, Adrian A; Tsao, Ming-Sound MS

Publication Date: 2023

Variant appearance in text: KRAS: A146P

PubMed Link: 36950276

Variant Present in the following documents:

• Main text
• 10.1177_17588359231160141.pdf

View BVdb publication page

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KRAS, NRAS, BRAF, HER2 and MSI Status in a Large Consecutive Series of Colorectal Carcinomas.

International Journal Of Molecular Sciences

Martianov, Aleksandr S AS; Mitiushkina, Natalia V NV; Ershova, Anastasia N AN; Martynenko, Darya E DE; Bubnov, Mikhail G MG; Amankwah, Priscilla P; Yanus, Grigory A GA; Aleksakhina, Svetlana N SN; Tiurin, Vladislav I VI; Venina, Aigul R AR; Anuskina, Aleksandra A AA; Gorgul, Yuliy A YA; Shestakova, Anna D AD; Maidin, Mikhail A MA; Belyaev, Alexey M AM; Baboshkina, Liliya S LS; Iyevleva, Aglaya G AG; Imyanitov, Evgeny N EN

Publication Date: 2023-03-02

Variant appearance in text: KRAS: A146P

PubMed Link: 36902296

Variant Present in the following documents:

• Main text
• ijms-24-04868.pdf

View BVdb publication page

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High-risk multiple myeloma predicted by circulating plasma cells and its genetic characteristics.

Frontiers In Oncology

Xia, Yuan Y; Shen, Na N; Zhang, Run R; Wu, Yujie Y; Shi, Qinglin Q; Li, Jianyong J; Chen, Lijuan L; Xu, Min M; Jin, Yuanyuan Y

Publication Date: 2023

Variant appearance in text: rs121913527

PubMed Link: 36845679

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

View BVdb publication page

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Network expansion of genetic associations defines a pleiotropy map of human cell biology.

Nature Genetics

Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P

Publication Date: 2023-02-23

Variant appearance in text: KRAS: 436G>C; Ala146Pro

PubMed Link: 36823319

Variant Present in the following documents:

• 41588_2023_1327_MOESM4_ESM.xlsx, sheet 6

View BVdb publication page

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Dynamics of age- versus therapy-related clonal hematopoiesis in long-term survivors of pediatric cancer.

Cancer Discovery

Hagiwara, Kohei K; Natarajan, Sivaraman S; Wang, Zhaoming Z; Zubair, Haseeb H; Mulder, Heather L HL; Dong, Li L; Plyler, Emily M EM; Thimmaiah, Padma P; Ma, Xiaotu X; Ness, Kirsten K KK; Li, Zhenghong Z; Mulrooney, Daniel A DA; Wilson, Carmen L CL; Yasui, Yutaka Y; Hudson, Melissa M MM; Easton, John J; Robison, Leslie L LL; Zhang, Jinghui J

Publication Date: 2023-02-08

Variant appearance in text: KRAS: A146P

PubMed Link: 36751942

Variant Present in the following documents:

• cd-22-0956_tables_s2_s7_s8_s9_suppst1.xlsx, sheet 1
• cd-22-0956_tables_s2_s7_s8_s9_suppst1.xlsx, sheet 2
• cd-22-0956_tables_s2_s7_s8_s9_suppst1.xlsx, sheet 4

View BVdb publication page

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Spectrum and clinical features of gene mutations in Chinese pediatric acute lymphoblastic leukemia.

Bmc Pediatrics

Shen, Diying D; Liu, Lixia L; Xu, Xiaojun X; Song, Hua H; Zhang, Jingying J; Xu, Weiqun W; Zhao, Fenying F; Liang, Juan J; Liao, Chan C; Wang, Yan Y; Xia, Tian T; Wang, Chengcheng C; Lou, Feng F; Cao, Shanbo S; Qin, Jiayue J; Tang, Yongmin Y

Publication Date: 2023-02-04

Variant appearance in text: KRAS: 436G>C; A146P

PubMed Link: 36739388

Variant Present in the following documents:

• 12887_2023_3856_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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An innovative single-base extension method for synchronous detection of point mutations and MSI status in colorectal cancer.

Cancer Medicine

Liang, Li L; Li, Xin X; Nong, Lin L; Cai, Weijing W; Zhang, Jixin J; Liu, Ping P; Li, Ting T

Publication Date: 2022-12-30

Variant appearance in text: KRAS: A146P

PubMed Link: 36583506

Variant Present in the following documents:

View BVdb publication page

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Targeting of colorectal cancer organoids with zoledronic acid conjugated to the anti-EGFR antibody cetuximab.

Journal For Immunotherapy Of Cancer

Benelli, Roberto R; Costa, Delfina D; Salvini, Laura L; Tardito, Samuele S; Tosetti, Francesca F; Villa, Federico F; Zocchi, Maria Raffaella MR; Poggi, Alessandro A

Publication Date: 2022-12

Variant appearance in text: KRAS: A146P

PubMed Link: 36543375

Variant Present in the following documents:

• jitc-2022-005660supp001.pdf

View BVdb publication page

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Transcriptome-based molecular subtypes and differentiation hierarchies improve the classification framework of acute myeloid leukemia.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Cheng, Wen-Yan WY; Li, Jian-Feng JF; Zhu, Yong-Mei YM; Lin, Xiang-Jie XJ; Wen, Li-Jun LJ; Zhang, Fan F; Zhang, Yu-Liang YL; Zhao, Ming M; Fang, Hai H; Wang, Sheng-Yue SY; Lin, Xiao-Jing XJ; Qiao, Niu N; Yin, Wei W; Zhang, Jia-Nan JN; Dai, Yu-Ting YT; Jiang, Lu L; Sun, Xiao-Jian XJ; Xu, Yi Y; Zhang, Tong-Tong TT; Chen, Su-Ning SN; Zhu, Hong-Hu HH; Chen, Zhu Z; Jin, Jie J; Wu, De-Pei DP; Shen, Yang Y; Chen, Sai-Juan SJ

Publication Date: 2022-12-06

Variant appearance in text: KRAS: 436G>C; A146P

PubMed Link: 36442087

Variant Present in the following documents:

• pnas.2211429119.sd02.xlsx, sheet 1

View BVdb publication page

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A sex-informed approach to improve the personalised decision making process in myelodysplastic syndromes: a multicentre, observational cohort study.

The Lancet. Haematology

,

Publication Date: 2022-11-24

Variant appearance in text: KRAS: 436G>C; A146P

PubMed Link: 36436542

Variant Present in the following documents:

• mmc2.xlsx, sheet 1

View BVdb publication page

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Somatic mutation distribution across tumour cohorts provides a signal for positive selection in cancer.

Nature Communications

Boström, Martin M; Larsson, Erik E

Publication Date: 2022-11-17

Variant appearance in text: KRAS: A146P

PubMed Link: 36396655

Variant Present in the following documents:

• 41467_2022_34746_MOESM10_ESM.xlsx, sheet 1

View BVdb publication page

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Enhancing an Oxidative "Trojan Horse" Action of Vitamin C with Arsenic Trioxide for Effective Suppression of KRAS-Mutant Cancers: A Promising Path at the Bedside.

Cells

Burska, Agata N AN; Ilyassova, Bayansulu B; Dildabek, Aruzhan A; Khamijan, Medina M; Begimbetova, Dinara D; Molnár, Ferdinand F; Sarbassov, Dos D DD

Publication Date: 2022-11-01

Variant appearance in text: KRAS: A146P

PubMed Link: 36359850

Variant Present in the following documents:

• Main text
• cells-11-03454.pdf

View BVdb publication page

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Prevalence and patterns of mutations in RAS/RAF/MEK/ERK/MAPK signaling pathway in colorectal cancer in North Africa.

Bmc Cancer

Jafari, Meryem M; Laraqui, Abdelilah A; Baba, Walid W; Benmokhtar, Soukaina S; Zaitouni, Sara El SE; Ali, Abdelmounaim Ait AA; Bounaim, Ahmed A; Moujahid, Mountassir M; Tanz, Rachid R; Mahfoud, Tarik T; Sbitti, Yassir Y; Annaz, Hicham El HE; Abi, Rachid R; Tagajdid, Mohamed Rida MR; Kochri, Safae El SE; Lahlou, Idriss Amine IA; Hsaini, Houda El HE; Belayachi, Lamiae L; Benjouad, Abdelaziz A; Ichou, Mohammed M; En-Nya, Amina A; Ennibi, Khalid K

Publication Date: 2022-11-07

Variant appearance in text: KRAS: 436G>C; Ala146Pro

PubMed Link: 36344948

Variant Present in the following documents:

• Main text
• 12885_2022_Article_10235.pdf

View BVdb publication page

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Genomic landscape, immune characteristics and prognostic mutation signature of cervical cancer in China.

Bmc Medical Genomics

Liu, Jing J; Li, Zirong Z; Lu, Ting T; Pan, Junping J; Li, Li L; Song, Yanwen Y; Hu, Dan D; Zhuo, Yanhong Y; Chen, Ying Y; Xu, Qin Q

Publication Date: 2022-11-04

Variant appearance in text: KRAS: 436G>C; A146P; rs121913527

PubMed Link: 36333792

Variant Present in the following documents:

• 12920_2022_1376_MOESM1_ESM.xlsx, sheet 1

View BVdb publication page

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RaScALL: Rapid (Ra) screening (Sc) of RNA-seq data for prognostically significant genomic alterations in acute lymphoblastic leukaemia (ALL).

Plos Genetics

Rehn, Jacqueline J; Mayoh, Chelsea C; Heatley, Susan L SL; McClure, Barbara J BJ; Eadie, Laura N LN; Schutz, Caitlin C; Yeung, David T DT; Cowley, Mark J MJ; Breen, James J; White, Deborah L DL

Publication Date: 2022-10

Variant appearance in text: KRAS: A146P

PubMed Link: 36251721

Variant Present in the following documents:

• Main text
• pgen.1010300.pdf

View BVdb publication page

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Duplex Sequencing Uncovers Recurrent Low-frequency Cancer-associated Mutations in Infant and Childhood KMT2A-rearranged Acute Leukemia.

Hemasphere

Pilheden, Mattias M; Ahlgren, Louise L; Hyrenius-Wittsten, Axel A; Gonzalez-Pena, Veronica V; Sturesson, Helena H; Hansen Marquart, Hanne Vibeke HV; Lausen, Birgitte B; Castor, Anders A; Pronk, Cornelis Jan CJ; Barbany, Gisela G; Pokrovskaja Tamm, Katja K; Fogelstrand, Linda L; Lohi, Olli O; Norén-Nyström, Ulrika U; Asklin, Johanna J; Chen, Yilun Y; Song, Guangchun G; Walsh, Michael M; Ma, Jing J; Zhang, Jinghui J; Saal, Lao H LH; Gawad, Charles C; Hagström-Andersson, Anna K AK

Publication Date: 2022-10

Variant appearance in text: KRAS: A146P

PubMed Link: 36204688

Variant Present in the following documents:

• hs9-6-e785-s001.xlsx, sheet 6

View BVdb publication page

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Molecular Biology and Therapeutic Perspectives for K-Ras Mutant Non-Small Cell Lung Cancers.

Cancers

Cekani, Elona E; Epistolio, Samantha S; Dazio, Giulia G; Cefalì, Marco M; Wannesson, Luciano L; Frattini, Milo M; Froesch, Patrizia P

Publication Date: 2022-08-24

Variant appearance in text: KRAS: 436G>C; A146P

PubMed Link: 36077640

Variant Present in the following documents:

• cancers-14-04103.pdf

View BVdb publication page

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Brown Tumors Belong to the Spectrum of KRAS -driven Neoplasms.

The American Journal Of Surgical Pathology

Turek, Daniel D; Haefliger, Simon S; Ameline, Baptiste B; Alborelli, Ilaria I; Calgua, Byron B; Hartmann, Wolfgang W; Harder, Dorothee D; Flanagan, Adrienne M AM; Amary, Fernanda F; Baumhoer, Daniel D

Publication Date: 2022-11-01

Variant appearance in text: KRAS: A146P

PubMed Link: 36040039

Variant Present in the following documents:

• pas-46-1577.pdf

View BVdb publication page

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Distinguishing STAT3/STAT5B Mutated Large Granular Lymphocyte Leukemia from Myeloid Neoplasms by Genetic Profiling.

Blood Advances

Kavesh, Mark M; Mohebnasab, Maedeh M; Angel, Marcela Riveros MR; Xie, Wei W; Raess, Philipp W PW; Cui, Wei W; Press, Richard D RD; Yang, Guang G; Li, Peng P

Publication Date: 2022-08-08

Variant appearance in text: KRAS: 436G>C; A146P

PubMed Link: 35939786

Variant Present in the following documents:

• BLOODA_ADV-2022-008192-mmc1.pdf

View BVdb publication page

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Genomic Landscape of RTK/RAS Pathway and Tumor Immune Infiltration as Prognostic Indicator of Lung Adenocarcinoma.

Frontiers In Oncology

Yin, Xiang-Qian XQ; Yin, Xue-Hui XH; Yu, Ya-Qin YQ; Xu, Lang L; Zhang, Mao M

Publication Date: 2022

Variant appearance in text: N/A

PubMed Link: 35936718

Variant Present in the following documents:

View BVdb publication page

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Genome-wide analyses of 200,453 individuals yield new insights into the causes and consequences of clonal hematopoiesis.

Nature Genetics

Kar, Siddhartha P SP; Quiros, Pedro M PM; Gu, Muxin M; Jiang, Tao T; Mitchell, Jonathan J; Langdon, Ryan R; Iyer, Vivek V; Barcena, Clea C; Vijayabaskar, M S MS; Fabre, Margarete A MA; Carter, Paul P; Petrovski, Slavé S; Burgess, Stephen S; Vassiliou, George S GS

Publication Date: 2022-08

Variant appearance in text: KRAS: A146P

PubMed Link: 35835912

Variant Present in the following documents:

• 41588_2022_1121_MOESM3_ESM.xlsx, sheet 2
• 41588_2022_1121_MOESM3_ESM.xlsx, sheet 4

View BVdb publication page

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Longitudinal dynamics of clonal hematopoiesis identifies gene-specific fitness effects.

Nature Medicine

Robertson, Neil A NA; Latorre-Crespo, Eric E; Terradas-Terradas, Maria M; Lemos-Portela, Jorge J; Purcell, Alison C AC; Livesey, Benjamin J BJ; Hillary, Robert F RF; Murphy, Lee L; Fawkes, Angie A; MacGillivray, Louise L; Copland, Mhairi M; Marioni, Riccardo E RE; Marsh, Joseph A JA; Harris, Sarah E SE; Cox, Simon R SR; Deary, Ian J IJ; Schumacher, Linus J LJ; Kirschner, Kristina K; Chandra, Tamir T

Publication Date: 2022-07

Variant appearance in text: KRAS: 436G>C; A146P

PubMed Link: 35788175

Variant Present in the following documents:

• 41591_2022_Article_1883.pdf
• 41591_2022_1883_MOESM3_ESM.xlsx, sheet 5
• 41591_2022_1883_MOESM3_ESM.xlsx, sheet 4

View BVdb publication page

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The genetic heterogeneity and drug resistance mechanisms of relapsed refractory multiple myeloma.

Nature Communications

Vo, Josh N JN; Wu, Yi-Mi YM; Mishler, Jeanmarie J; Hall, Sarah S; Mannan, Rahul R; Wang, Lisha L; Ning, Yu Y; Zhou, Jin J; Hopkins, Alexander C AC; Estill, James C JC; Chan, Wallace K B WKB; Yesil, Jennifer J; Cao, Xuhong X; Rao, Arvind A; Tsodikov, Alexander A; Talpaz, Moshe M; Cole, Craig E CE; Ye, Jing C JC; , ; Bergsagel, P Leif PL; Auclair, Daniel D; Cho, Hearn Jay HJ; Robinson, Dan R DR; Chinnaiyan, Arul M AM

Publication Date: 2022-06-29

Variant appearance in text: KRAS: 436G>C; Ala146Pro

PubMed Link: 35768438

Variant Present in the following documents:

• 41467_2022_31430_MOESM4_ESM.xlsx, sheet 1

View BVdb publication page

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Clinical genomic profiling in the management of patients with soft tissue and bone sarcoma.

Nature Communications

Gounder, Mrinal M MM; Agaram, Narasimhan P NP; Trabucco, Sally E SE; Robinson, Victoria V; Ferraro, Richard A RA; Millis, Sherri Z SZ; Krishnan, Anita A; Lee, Jessica J; Attia, Steven S; Abida, Wassim W; Drilon, Alexander A; Chi, Ping P; Angelo, Sandra P D' SP; Dickson, Mark A MA; Keohan, Mary Lou ML; Kelly, Ciara M CM; Agulnik, Mark M; Chawla, Sant P SP; Choy, Edwin E; Chugh, Rashmi R; Meyer, Christian F CF; Myer, Parvathi A PA; Moore, Jessica L JL; Okimoto, Ross A RA; Pollock, Raphael E RE; Ravi, Vinod V; Singh, Arun S AS; Somaiah, Neeta N; Wagner, Andrew J AJ; Healey, John H JH; Frampton, Garrett M GM; Venstrom, Jeffrey M JM; Ross, Jeffrey S JS; Ladanyi, Marc M; Singer, Samuel S; Brennan, Murray F MF; Schwartz, Gary K GK; Lazar, Alexander J AJ; Thomas, David M DM; Maki, Robert G RG; Tap, William D WD; Ali, Siraj M SM; Jin, Dexter X DX

Publication Date: 2022-06-15

Variant appearance in text: KRAS: A146P

PubMed Link: 35705558

Variant Present in the following documents:

• 41467_2022_30496_MOESM2_ESM.xls, sheet 1

View BVdb publication page

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Clonal evolution after treatment pressure in multiple myeloma: heterogenous genomic aberrations and transcriptomic convergence.

Leukemia

Misund, Kristine K; Hofste Op Bruinink, Davine D; Coward, Eivind E; Hoogenboezem, Remco M RM; Rustad, Even Holth EH; Sanders, Mathijs A MA; Rye, Morten M; Sponaas, Anne-Marit AM; van der Holt, Bronno B; Zweegman, Sonja S; Hovig, Eivind E; Meza-Zepeda, Leonardo A LA; Sundan, Anders A; Myklebost, Ola O; Sonneveld, Pieter P; Waage, Anders A

Publication Date: 2022-07

Variant appearance in text: KRAS: A146P

PubMed Link: 35643867

Variant Present in the following documents:

• 41375_2022_1597_MOESM3_ESM.xlsx, sheet 7
• 41375_2022_1597_MOESM4_ESM.xlsx, sheet 1

View BVdb publication page

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Pathophysiologic and clinical implications of molecular profiles resultant from deletion 5q.

Ebiomedicine

Adema, Vera V; Palomo, Laura L; Walter, Wencke W; Mallo, Mar M; Hutter, Stephan S; La Framboise, Thomas T; Arenillas, Leonor L; Meggendorfer, Manja M; Radivoyevitch, Tomas T; Xicoy, Blanca B; Pellagatti, Andrea A; Haferlach, Claudia C; Boultwood, Jacqueline J; Kern, Wolfgang W; Visconte, Valeria V; Sekeres, Mikkael M; Barnard, John J; Haferlach, Torsten T; Solé, Francesc F; Maciejewski, Jaroslaw P JP

Publication Date: 2022-06

Variant appearance in text: KRAS: 436G>C; Ala146Pro

PubMed Link: 35617825

Variant Present in the following documents:

• mmc3.xlsx, sheet 1

View BVdb publication page

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Performance of Idylla™ RAS-BRAF mutation test for formalin-fixed paraffin-embedded tissues of colorectal cancer.

International Journal Of Clinical Oncology

Makutani, Yusuke Y; Sakai, Kazuko K; Yamada, Masahiro M; Wada, Toshiaki T; Chikugo, Takaaki T; Satou, Takao T; Iwasa, Yoko Y; Yamamoto, Hidekazu H; de Velasco, Marco A MA; Nishio, Kazuto K; Kawamura, Junichiro J

Publication Date: 2022-07

Variant appearance in text: KRAS: 436G>C; A146P

PubMed Link: 35474548

Variant Present in the following documents:

• 10147_2022_2167_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

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Clinically actionable cancer somatic variants (CACSV): a tumor interpreted dataset for analytical workflows.

Bmc Medical Genomics

Sobahy, Turki M TM; Tashkandi, Ghassan G; Bahussain, Donya D; Al-Harbi, Raneem R

Publication Date: 2022-04-25

Variant appearance in text: KRAS: 436G>C; A146P

PubMed Link: 35468810

Variant Present in the following documents:

• 12920_2022_1235_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Concurrent RAS and RAS/BRAF V600E Variants in Colorectal Cancer: More Frequent Than Expected? A Case Report.

Frontiers In Oncology

Zelli, Veronica V; Parisi, Alessandro A; Patruno, Leonardo L; Cannita, Katia K; Ficorella, Corrado C; Luzi, Carla C; Compagnoni, Chiara C; Zazzeroni, Francesca F; Alesse, Edoardo E; Tessitore, Alessandra A

Publication Date: 2022

Variant appearance in text: KRAS: A146P

PubMed Link: 35463316

Variant Present in the following documents:

• Main text
• fonc-12-863639.pdf

View BVdb publication page

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Response prediction and risk stratification of patients with rectal cancer after neoadjuvant therapy through an analysis of circulating tumour DNA.

Ebiomedicine

Liu, Wenyang W; Li, Yifei Y; Tang, Yuan Y; Song, Qianqian Q; Wang, Jingjing J; Li, Ning N; Chen, Silin S; Shi, Jinming J; Wang, Shulian S; Li, Yexiong Y; Jiao, Yuchen Y; Zeng, Yixin Y; Jin, Jing J

Publication Date: 2022-04

Variant appearance in text: KRAS: A146P; rs121913527

PubMed Link: 35306340

Variant Present in the following documents:

• mmc3.xlsx, sheet 2

View BVdb publication page

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Direct Targeting KRAS Mutation in Non-Small Cell Lung Cancer: Focus on Resistance.

Cancers

Reita, Damien D; Pabst, Lucile L; Pencreach, Erwan E; Guérin, Eric E; Dano, Laurent L; Rimelen, Valérie V; Voegeli, Anne-Claire AC; Vallat, Laurent L; Mascaux, Céline C; Beau-Faller, Michèle M

Publication Date: 2022-03-04

Variant appearance in text: KRAS: A146P

PubMed Link: 35267628

Variant Present in the following documents:

• Main text
• cancers-14-01321.pdf

View BVdb publication page

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Custom multi‑tumor next‑generation sequencing panel for routine molecular diagnosis of solid tumors: Validation and results from three‑year clinical use.

International Journal Of Molecular Medicine

Chevrier, Sandy S; Brasselet, Astrid A; Carnet, Marion M; Chevriaux, Angélique A; Gibeaud, Anne A; Jourdain, Marine M; Mananet, Hugo H; Truntzer, Caroline C; Beltjens, Françoise F; Charon-Barra, Céline C; Arnould, Laurent L; Albuisson, Juliette J; Comte, Anthony A; Derangère, Valentin V; Goussot, Vincent V; Boidot, Romain R

Publication Date: 2022-05

Variant appearance in text: KRAS: 436G>C; Ala146Pro

PubMed Link: 35244186

Variant Present in the following documents:

• Supplementary_Data2.xlsx, sheet 1
• Supplementary_Data3.xlsx, sheet 1

View BVdb publication page

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Gene fusions and oncogenic mutations in MLH1 deficient and BRAFV600E wild-type colorectal cancers.

Virchows Archiv : An International Journal Of Pathology

Ukkola, Iiris I; Nummela, Pirjo P; Kero, Mia M; Tammio, Hanna H; Tuominen, Jenni J; Kairisto, Veli V; Kallajoki, Markku M; Haglund, Caj C; Peltomäki, Päivi P; Kytölä, Soili S; Ristimäki, Ari A

Publication Date: 2022-04

Variant appearance in text: KRAS: A146P

PubMed Link: 35237889

Variant Present in the following documents:

• 428_2022_3302_MOESM1_ESM.pdf

View BVdb publication page

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The Molecular Tumor Board Portal supports clinical decisions and automated reporting for precision oncology.

Nature Cancer

Tamborero, David D; Dienstmann, Rodrigo R; Rachid, Maan Haj MH; Boekel, Jorrit J; Lopez-Fernandez, Adria A; Jonsson, Markus M; Razzak, Ali A; Braña, Irene I; De Petris, Luigi L; Yachnin, Jeffrey J; Baird, Richard D RD; Loriot, Yohann Y; Massard, Christophe C; Martin-Romano, Patricia P; Opdam, Frans F; Schlenk, Richard F RF; Vernieri, Claudio C; Masucci, Michele M; Villalobos, Xenia X; Chavarria, Elena E; , ; Balmaña, Judith J; Apolone, Giovanni G; Caldas, Carlos C; Bergh, Jonas J; Ernberg, Ingemar I; Fröhling, Stefan S; Garralda, Elena E; Karlsson, Claes C; Tabernero, Josep J; Voest, Emile E; Rodon, Jordi J; Lehtiö, Janne J

Publication Date: 2022-02

Variant appearance in text: KRAS: Ala146Pro

PubMed Link: 35221333

Variant Present in the following documents:

• 43018_2022_332_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

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Dynamics of RAS/BRAF Mutations in cfDNA from Metastatic Colorectal Carcinoma Patients Treated with Polychemotherapy and Anti-EGFR Monoclonal Antibodies.

Cancers

Rachiglio, Anna Maria AM; Forgione, Laura L; Pasquale, Raffaella R; Barone, Carlo Antonio CA; Maiello, Evaristo E; Antonuzzo, Lorenzo L; Cassata, Antonino A; Tonini, Giuseppe G; Bordonaro, Roberto R; Rosati, Gerardo G; Zaniboni, Alberto A; Lonardi, Sara S; Ferrari, Daris D; Frassineti, Giovanni Luca GL; Tamberi, Stefano S; Pisconti, Salvatore S; Di Fabio, Francesca F; Roma, Cristin C; Orlandi, Armando A; Latiano, Tiziana T; Damato, Angela A; Tortora, Giampaolo G; Pinto, Carmine C; Normanno, Nicola N

Publication Date: 2022-02-18

Variant appearance in text: KRAS: A146P

PubMed Link: 35205799

Variant Present in the following documents:

• cancers-14-01052.pdf

View BVdb publication page

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Mutational landscape of circulating tumor DNA identifies distinct molecular features associated with therapeutic response in patients with metastatic colorectal cancer.

Therapeutic Advances In Medical Oncology

Shi, Min M; Yuan, Hong H; Ji, Jun J; Zhang, Shouwei S; Li, Qingyuan Q; Chen, Yawei Y; Gong, Xiaoli X; Zhu, Zhenggang Z; Zhang, Jun J

Publication Date: 2022

Variant appearance in text: rs121913527

PubMed Link: 35096147

Variant Present in the following documents:

• sj-xls-4-tam-10.1177_17588359211070643.xls, sheet 1

View BVdb publication page

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Single-cell analysis of gastric pre-cancerous and cancer lesions reveals cell lineage diversity and intratumoral heterogeneity.

Npj Precision Oncology

Kim, Jihyun J; Park, Charny C; Kim, Kwang H KH; Kim, Eun Hye EH; Kim, Hyunki H; Woo, Jong Kyu JK; Seong, Je Kyung JK; Nam, Ki Taek KT; Lee, Yong Chan YC; Cho, Soo Young SY

Publication Date: 2022-01-27

Variant appearance in text: rs121913527

PubMed Link: 35087207

Variant Present in the following documents:

• 41698_2022_251_MOESM1_ESM.pdf

View BVdb publication page

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KLF3 and PAX6 are candidate driver genes in late-stage, MSI-hypermutated endometrioid endometrial carcinomas.

Plos One

Rudd, Meghan L ML; Hansen, Nancy F NF; Zhang, Xiaolu X; Urick, Mary Ellen ME; Zhang, Suiyuan S; Merino, Maria J MJ; , ; Mullikin, James C JC; Brody, Lawrence C LC; Bell, Daphne W DW

Publication Date: 2022

Variant appearance in text: rs121913527

PubMed Link: 35081118

Variant Present in the following documents:

• pone.0251286.s005.xlsx, sheet 8

View BVdb publication page

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KLF3 and PAX6 are candidate driver genes in late-stage, MSI-hypermutated endometrioid endometrial carcinomas.

Plos One

Rudd, Meghan L ML; Hansen, Nancy F NF; Zhang, Xiaolu X; Urick, Mary Ellen ME; Zhang, Suiyuan S; Merino, Maria J MJ; , ; Mullikin, James C JC; Brody, Lawrence C LC; Bell, Daphne W DW

Publication Date: 2022

Variant appearance in text: rs121913527

PubMed Link: 35081118

Variant Present in the following documents:

• pone.0251286.s005.xlsx, sheet 8

View BVdb publication page

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Identification of Immune-Related Gene Signatures in Lung Adenocarcinoma and Lung Squamous Cell Carcinoma.

Frontiers In Immunology

Li, Na N; Wang, Jiahong J; Zhan, Xianquan X

Publication Date: 2021

Variant appearance in text: KRAS: 436G>C; Ala146Pro

PubMed Link: 34887858

Variant Present in the following documents:

• Table_3.xlsx, sheet 1

View BVdb publication page

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Concordance of acquired mutations between metastatic lesions and liquid biopsy in metastatic colorectal cancer.

Future Science Oa

Taniguchi, Fumitaka F; Nyuya, Akihiro A; Toshima, Toshiaki T; Yasui, Kazuya K; Mori, Yoshiko Y; Okawaki, Makoto M; Kishimoto, Hiroyuki H; Umeda, Yuzo Y; Fujiwara, Toshiyoshi T; Tanioka, Hiroaki H; Yamaguchi, Yoshiyuki Y; Goel, Ajay A; Nagasaka, Takeshi T

Publication Date: 2021-12

Variant appearance in text: KRAS: A146P

PubMed Link: 34840814

Variant Present in the following documents:

• fsoa-07-757.pdf

View BVdb publication page

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Mutational landscape of high-grade B-cell lymphoma with MYC-, BCL2 and/or BCL6 rearrangements characterized by whole-exome sequencing.

Haematologica

Künstner, Axel A; Witte, Hanno M HM; Riedl, Jörg J; Bernard, Veronica V; Stölting, Stephanie S; Merz, Hartmut H; Olschewski, Vito V; Peter, Wolfgang W; Ketzer, Julius J; Busch, Yannik Y; Trojok, Peter P; Bubnoff, Nikolas von NV; Busch, Hauke H; Feller, Alfred C AC; Gebauer, Niklas N

Publication Date: 2022-08-01

Variant appearance in text: KRAS: A146P

PubMed Link: 34788985

Variant Present in the following documents:

• 2021_279631_KUNSTNER_TABS5_SUPPL.xlsx, sheet 1

View BVdb publication page

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Evaluation of the MGISEQ-2000 Sequencing Platform for Illumina Target Capture Sequencing Libraries.

Frontiers In Genetics

Lang, Jidong J; Zhu, Rongrong R; Sun, Xue X; Zhu, Siyu S; Li, Tianbao T; Shi, Xiaoli X; Sun, Yanqi Y; Yang, Zhou Z; Wang, Weiwei W; Bing, Pingping P; He, Binsheng B; Tian, Geng G

Publication Date: 2021

Variant appearance in text: KRAS: A146P

PubMed Link: 34777467

Variant Present in the following documents:

• DataSheet1.xlsx, sheet 4

View BVdb publication page

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Clinical Utility of Plasma-Based Comprehensive Molecular Profiling in Advanced Non-Small-Cell Lung Cancer.

Jco Precision Oncology

Schouten, Robert D RD; Vessies, Daan C L DCL; Bosch, Linda J W LJW; Barlo, Nicole P NP; van Lindert, Anne S R ASR; Cillessen, Saskia A G M SAGM; van den Broek, Daan D; van den Heuvel, Michel M MM; Monkhorst, Kim K

Publication Date: 2021-07

Variant appearance in text: KRAS: A146P

PubMed Link: 34632253

Variant Present in the following documents:

• po-5-1112.pdf

View BVdb publication page

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Clinical Utility of Plasma-Based Comprehensive Molecular Profiling in Advanced Non-Small-Cell Lung Cancer.

Jco Precision Oncology

Schouten, Robert D RD; Vessies, Daan C L DCL; Bosch, Linda J W LJW; Barlo, Nicole P NP; van Lindert, Anne S R ASR; Cillessen, Saskia A G M SAGM; van den Broek, Daan D; van den Heuvel, Michel M MM; Monkhorst, Kim K

Publication Date: 2021-07

Variant appearance in text: KRAS: A146P

PubMed Link: 34632253

Variant Present in the following documents:

• po-5-1112.pdf

View BVdb publication page

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: KRAS: A146P

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

View BVdb publication page

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Molecular profiling of advanced malignancies guides first-line N-of-1 treatments in the I-PREDICT treatment-naïve study.

Genome Medicine

Sicklick, Jason K JK; Kato, Shumei S; Okamura, Ryosuke R; Patel, Hitendra H; Nikanjam, Mina M; Fanta, Paul T PT; Hahn, Michael E ME; De, Pradip P; Williams, Casey C; Guido, Jessica J; Solomon, Benjamin M BM; McKay, Rana R RR; Krie, Amy A; Boles, Sarah G SG; Ross, Jeffrey S JS; Lee, J Jack JJ; Leyland-Jones, Brian B; Lippman, Scott M SM; Kurzrock, Razelle R

Publication Date: 2021-10-04

Variant appearance in text: KRAS: A146P

PubMed Link: 34607609

Variant Present in the following documents:

• 13073_2021_969_MOESM1_ESM.xlsx, sheet 1
• 13073_2021_969_MOESM1_ESM.xlsx, sheet 2

View BVdb publication page

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Characterization of Non-Small-Cell Lung Cancers With MET Exon 14 Skipping Alterations Detected in Tissue or Liquid: Clinicogenomics and Real-World Treatment Patterns.

Jco Precision Oncology

Lee, Jessica K JK; Madison, Russell R; Classon, Anthony A; Gjoerup, Ole O; Rosenzweig, Mark M; Frampton, Garrett M GM; Alexander, Brian M BM; Oxnard, Geoffrey R GR; Venstrom, Jeffrey M JM; Awad, Mark M MM; Schrock, Alexa B AB

Publication Date: 2021

Variant appearance in text: KRAS: A146P

PubMed Link: 34476332

Variant Present in the following documents:

• po-5-po.21.00122.pdf

View BVdb publication page

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Pretreatment 18F-FDG PET/CT Imaging Predicts the KRAS/NRAS/BRAF Gene Mutational Status in Colorectal Cancer.

Journal Of Oncology

He, Peng P; Zou, Yuan Y; Qiu, Jia J; Yang, Tianhong T; Peng, Lei L; Zhang, Xiangsong X

Publication Date: 2021

Variant appearance in text: KRAS: Ala146Pro

PubMed Link: 34239564

Variant Present in the following documents:

• Main text
• JO2021-6687291.pdf

View BVdb publication page

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Clinical and prognostic features of patients with detailed RAS/BRAF-mutant colorectal cancer in Japan.

Bmc Cancer

Ikoma, Tatsuki T; Shimokawa, Mototsugu M; Kotaka, Masahito M; Matsumoto, Toshihiko T; Nagai, Hiroki H; Boku, Shogen S; Shibata, Nobuhiro N; Yasui, Hisateru H; Satake, Hironaga H

Publication Date: 2021-05-07

Variant appearance in text: KRAS: A146P

PubMed Link: 33962575

Variant Present in the following documents:

• Main text

View BVdb publication page

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Spatially interacting phosphorylation sites and mutations in cancer.

Nature Communications

Huang, Kuan-Lin KL; Scott, Adam D AD; Zhou, Daniel Cui DC; Wang, Liang-Bo LB; Weerasinghe, Amila A; Elmas, Abdulkadir A; Liu, Ruiyang R; Wu, Yige Y; Wendl, Michael C MC; Wyczalkowski, Matthew A MA; Baral, Jessika J; Sengupta, Sohini S; Lai, Chin-Wen CW; Ruggles, Kelly K; Payne, Samuel H SH; Raphael, Benjamin B; Fenyö, David D; Chen, Ken K; Mills, Gordon G; Ding, Li L

Publication Date: 2021-04-19

Variant appearance in text: KRAS: A146P

PubMed Link: 33875650

Variant Present in the following documents:

• 41467_2021_22481_MOESM4_ESM.xlsx, sheet 5
• 41467_2021_22481_MOESM4_ESM.xlsx, sheet 1

View BVdb publication page

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The Metabolic Landscape of RAS-Driven Cancers from biology to therapy.

Nature Cancer

Mukhopadhyay, Suman S; Vander Heiden, Matthew G MG; McCormick, Frank F

Publication Date: 2021-03

Variant appearance in text: KRAS: A146P

PubMed Link: 33870211

Variant Present in the following documents:

• NIHMS1684793-supplement-Supplementary_table.xls, sheet 3

View BVdb publication page

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The Metabolic Landscape of RAS-Driven Cancers from biology to therapy.

Nature Cancer

Mukhopadhyay, Suman S; Vander Heiden, Matthew G MG; McCormick, Frank F

Publication Date: 2021-03

Variant appearance in text: KRAS: A146P

PubMed Link: 33870211

Variant Present in the following documents:

• NIHMS1684793-supplement-Supplementary_table.xls, sheet 3

View BVdb publication page

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