KRAS c.400G>A ;(p.A134T)

Variant ID: 12-25378598-C-T

NM_004985.3(KRAS):c.400G>A;(p.A134T)

This variant was identified in 8 publications

View GRCh38 version.




Publications:


Clinical utility of liquid biopsy and integrative genomic profiling in early-stage and oligometastatic cancer patients treated with radiotherapy.

British Journal Of Cancer
Cifuentes, Guadalupe A GA; Santiago, Adrián A; Méndez Blanco, Lucía L; Fueyo, María M; López Martínez, Esther E; Soria, Raquel R; Martín López, Irene I; Cucarella Beltrán, Pepa P; Pardo-Coto, Pablo P; Rodriguez-Rubi, David D; Urquilla, Karla K; Durán, Noelia S NS; Álvarez, Rebeca R; Lago, Claudia G CG; Otero, Andrea A; Diñeiro, Marta M; Capín, Raquel R; Cadiñanos, Juan J; Cabanillas, Rubén R
Publication Date: 2022-12-22

Variant appearance in text: KRAS: Ala134Thr
PubMed Link: 36550207
Variant Present in the following documents:
  • Main text
View BVdb publication page



KRAS signaling in malignant pleural mesothelioma.

Embo Molecular Medicine
Marazioti, Antonia A; Krontira, Anthi C AC; Behrend, Sabine J SJ; Giotopoulou, Georgia A GA; Ntaliarda, Giannoula G; Blanquart, Christophe C; Bayram, Hasan H; Iliopoulou, Marianthi M; Vreka, Malamati M; Trassl, Lilith L; Pepe, Mario A A MAA; Hackl, Caroline M CM; Klotz, Laura V LV; Weiss, Stefanie A I SAI; Koch, Ina I; Lindner, Michael M; Hatz, Rudolph A RA; Behr, Juergen J; Wagner, Darcy E DE; Papadaki, Helen H; Antimisiaris, Sophia G SG; Jean, Didier D; Deshayes, Sophie S; Grégoire, Marc M; Kayalar, Özgecan Ö; Mortazavi, Deniz D; Dilege, Şükrü Ş; Tanju, Serhan S; Erus, Suat S; Yavuz, Ömer Ö; Bulutay, Pınar P; Fırat, Pınar P; Psallidas, Ioannis I; Spella, Magda M; Giopanou, Ioanna I; Lilis, Ioannis I; Lamort, Anne-Sophie AS; Stathopoulos, Georgios T GT
Publication Date: 2021-12-13

Variant appearance in text: KRAS: A134T
PubMed Link: 34898002
Variant Present in the following documents:
  • Main text
  • EMMM-14-e13631-s008.pdf
View BVdb publication page



KRAS signaling in malignant pleural mesothelioma.

Embo Molecular Medicine
Marazioti, Antonia A; Krontira, Anthi C AC; Behrend, Sabine J SJ; Giotopoulou, Georgia A GA; Ntaliarda, Giannoula G; Blanquart, Christophe C; Bayram, Hasan H; Iliopoulou, Marianthi M; Vreka, Malamati M; Trassl, Lilith L; Pepe, Mario A A MAA; Hackl, Caroline M CM; Klotz, Laura V LV; Weiss, Stefanie A I SAI; Koch, Ina I; Lindner, Michael M; Hatz, Rudolph A RA; Behr, Juergen J; Wagner, Darcy E DE; Papadaki, Helen H; Antimisiaris, Sophia G SG; Jean, Didier D; Deshayes, Sophie S; Grégoire, Marc M; Kayalar, Özgecan Ö; Mortazavi, Deniz D; Dilege, Şükrü Ş; Tanju, Serhan S; Erus, Suat S; Yavuz, Ömer Ö; Bulutay, Pınar P; Fırat, Pınar P; Psallidas, Ioannis I; Spella, Magda M; Giopanou, Ioanna I; Lilis, Ioannis I; Lamort, Anne-Sophie AS; Stathopoulos, Georgios T GT
Publication Date: 2022-02-07

Variant appearance in text: KRAS: A134T
PubMed Link: 34898002
Variant Present in the following documents:
  • Main text
  • EMMM-14-e13631-s008.pdf
View BVdb publication page



Establishment and characterization of a new human colon cancer cell line, PUMC-CRC1.

Scientific Reports
Bian, Xiaocui X; Cao, Fang F; Wang, Xiaowan X; Hou, Yuhong Y; Zhao, Haitao H; Liu, Yuqin Y
Publication Date: 2021-06-23

Variant appearance in text: KRAS: 400G>A; A134T
PubMed Link: 34162944
Variant Present in the following documents:
  • Main text
View BVdb publication page



Therapy-induced mutations drive the genomic landscape of relapsed acute lymphoblastic leukemia.

Blood
Li, Benshang B; Brady, Samuel W SW; Ma, Xiaotu X; Shen, Shuhong S; Zhang, Yingchi Y; Li, Yongjin Y; Szlachta, Karol K; Dong, Li L; Liu, Yu Y; Yang, Fan F; Wang, Ningling N; Flasch, Diane A DA; Myers, Matthew A MA; Mulder, Heather L HL; Ding, Lixia L; Liu, Yanling Y; Tian, Liqing L; Hagiwara, Kohei K; Xu, Ke K; Zhou, Xin X; Sioson, Edgar E; Wang, Tianyi T; Yang, Liu L; Zhao, Jie J; Zhang, Hui H; Shao, Ying Y; Sun, Hongye H; Sun, Lele L; Cai, Jiaoyang J; Sun, Hui-Ying HY; Lin, Ting-Nien TN; Du, Lijuan L; Li, Hui H; Rusch, Michael M; Edmonson, Michael N MN; Easton, John J; Zhu, Xiaofan X; Zhang, Jingliao J; Cheng, Cheng C; Raphael, Benjamin J BJ; Tang, Jingyan J; Downing, James R JR; Alexandrov, Ludmil B LB; Zhou, Bin-Bing S BS; Pui, Ching-Hon CH; Yang, Jun J JJ; Zhang, Jinghui J
Publication Date: 2020-01-02

Variant appearance in text: KRAS: A134T
PubMed Link: 31697823
Variant Present in the following documents:
  • Main text
View BVdb publication page



Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Publication Date: 2018

Variant appearance in text: KRAS: A134T
PubMed Link: 29698444
Variant Present in the following documents:
  • pone.0196434.s001.xlsx, sheet 3
  • pone.0196434.s001.xlsx, sheet 1
  • pone.0196434.s001.xlsx, sheet 2
View BVdb publication page



Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Nature Communications
Kis, Olena O; Kaedbey, Rayan R; Chow, Signy S; Danesh, Arnavaz A; Dowar, Mark M; Li, Tiantian T; Li, Zhihua Z; Liu, Jessica J; Mansour, Mark M; Masih-Khan, Esther E; Zhang, Tong T; Bratman, Scott V SV; Oza, Amit M AM; Kamel-Reid, Suzanne S; Trudel, Suzanne S; Pugh, Trevor J TJ
Publication Date: 2017-05-11

Variant appearance in text: KRAS: 400G>A
PubMed Link: 28492226
Variant Present in the following documents:
  • ncomms15086-s3.xlsx, sheet 1
View BVdb publication page



PIK3CA Mutations Contribute to Acquired Cetuximab Resistance in Patients with Metastatic Colorectal Cancer.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Xu, Jian-Ming JM; Wang, Yan Y; Wang, You-Liang YL; Wang, Yan Y; Liu, Tao T; Ni, Ming M; Li, Man-Sheng MS; Lin, Li L; Ge, Fei-Jiao FJ; Gong, Chun C; Gu, Jun-Yan JY; Jia, Ru R; Wang, He-Fei HF; Chen, Yu-Ling YL; Liu, Rong-Rui RR; Zhao, Chuan-Hua CH; Tan, Zhao-Li ZL; Jin, Yang Y; Zhu, Yun-Ping YP; Ogino, Shuji S; Qian, Zhi-Rong ZR
Publication Date: 2017-08-15

Variant appearance in text: KRAS: A134T
PubMed Link: 28424201
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genome-wide mutational landscape of mucinous carcinomatosis peritonei of appendiceal origin.

Genome Medicine
Alakus, Hakan H; Babicky, Michele L ML; Ghosh, Pradipta P; Yost, Shawn S; Jepsen, Kristen K; Dai, Yang Y; Arias, Angelo A; Samuels, Michael L ML; Mose, Evangeline S ES; Schwab, Richard B RB; Peterson, Michael R MR; Lowy, Andrew M AM; Frazer, Kelly A KA; Harismendy, Olivier O
Publication Date: 2014

Variant appearance in text: KRAS: A134T
PubMed Link: 24944587
Variant Present in the following documents:
  • gm559-S3.xls, sheet 12
View BVdb publication page