KRAS c.341T>C ;(p.V114A)

Variant ID: 12-25378657-A-G

NM_004985.3(KRAS):c.341T>C;(p.V114A)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


Spectrum of Mechanisms of Resistance to Crizotinib and Lorlatinib in ROS1 Fusion-Positive Lung Cancer.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Lin, Jessica J JJ; Choudhury, Noura J NJ; Yoda, Satoshi S; Zhu, Viola W VW; Johnson, Ted W TW; Sakhtemani, Ramin R; Dagogo-Jack, Ibiayi I; Digumarthy, Subba R SR; Lee, Charlotte C; Do, Andrew A; Peterson, Jennifer J; Prutisto-Chang, Kylie K; Malik, Wafa W; Hubbeling, Harper G HG; Langenbucher, Adam A; Schoenfeld, Adam J AJ; Falcon, Christina J CJ; Temel, Jennifer S JS; Sequist, Lecia V LV; Yeap, Beow Y BY; Lennerz, Jochen K JK; Shaw, Alice T AT; Lawrence, Michael S MS; Ou, Sai-Hong Ignatius SI; Hata, Aaron N AN; Drilon, Alexander A; Gainor, Justin F JF
Publication Date: 2021-05-15

Variant appearance in text: KRAS: V114A
PubMed Link: 33685866
Variant Present in the following documents:
  • Main text
View BVdb publication page



Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Publication Date: 2018

Variant appearance in text: KRAS: V114A
PubMed Link: 29698444
Variant Present in the following documents:
  • pone.0196434.s001.xlsx, sheet 1
  • pone.0196434.s001.xlsx, sheet 2
View BVdb publication page



Amplicon sequencing of colorectal cancer: variant calling in frozen and formalin-fixed samples.

Plos One
Betge, Johannes J; Kerr, Grainne G; Miersch, Thilo T; Leible, Svenja S; Erdmann, Gerrit G; Galata, Christian L CL; Zhan, Tianzuo T; Gaiser, Timo T; Post, Stefan S; Ebert, Matthias P MP; Horisberger, Karoline K; Boutros, Michael M
Publication Date: 2015

Variant appearance in text: KRAS: V114A
PubMed Link: 26010451
Variant Present in the following documents:
  • pone.0127146.s014.xlsx, sheet 3
View BVdb publication page