Development of syngeneic murine cell lines for use in immunocompetent orthotopic lung cancer models.
Cancer Cell International
Nolan, Kyle K; Verzosa, Gregory G; Cleaver, Tim T; Tippimanchai, Darinee D; DePledge, Lisa N LN; Wang, Xiao-Jing XJ; Young, Christian C; Le, Anh A; Doebele, Robert R; Li, Howard H; Malkoski, Stephen P SP
Dual PI3K/mTOR Inhibition in Colorectal Cancers with APC and PIK3CA Mutations.
Molecular Cancer Research : Mcr
Foley, Tyler M TM; Payne, Susan N SN; Pasch, Cheri A CA; Yueh, Alex E AE; Van De Hey, Dana R DR; Korkos, Demetra P DP; Clipson, Linda L; Maher, Molly E ME; Matkowskyj, Kristina A KA; Newton, Michael A MA; Deming, Dustin A DA
Colon Cancer Tumorigenesis Initiated by the H1047R Mutant PI3K.
Plos One
Yueh, Alexander E AE; Payne, Susan N SN; Leystra, Alyssa A AA; Van De Hey, Dana R DR; Foley, Tyler M TM; Pasch, Cheri A CA; Clipson, Linda L; Matkowskyj, Kristina A KA; Deming, Dustin A DA
PIK3CA mutations can initiate pancreatic tumorigenesis and are targetable with PI3K inhibitors.
Oncogenesis
Payne, S N SN; Maher, M E ME; Tran, N H NH; Van De Hey, D R DR; Foley, T M TM; Yueh, A E AE; Leystra, A A AA; Pasch, C A CA; Jeffrey, J J JJ; Clipson, L L; Matkowskyj, K A KA; Deming, D A DA
mTOR inhibition elicits a dramatic response in PI3K-dependent colon cancers.
Plos One
Deming, Dustin A DA; Leystra, Alyssa A AA; Farhoud, Mohammed M; Nettekoven, Laura L; Clipson, Linda L; Albrecht, Dawn D; Washington, Mary Kay MK; Sullivan, Ruth R; Weichert, Jamey P JP; Halberg, Richard B RB