KRAS c.311A>G ;(p.K104R)

Variant ID: 12-25378687-T-C

NM_004985.3(KRAS):c.311A>G;(p.K104R)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


KRAS Ubiquitination at Lysine 104 Retains Exchange Factor Regulation by Dynamically Modulating the Conformation of the Interface.

Iscience
Yin, Guowei G; Zhang, Jerry J; Nair, Vinay V; Truong, Vinh V; Chaia, Angelo A; Petela, Johnny J; Harrison, Joseph J; Gorfe, Alemayehu A AA; Campbell, Sharon L SL
Publication Date: 2020-08-10

Variant appearance in text: KRAS: K104R
PubMed Link: 32882514
Variant Present in the following documents:
  • Main text
  • main.pdf
  • mmc1.pdf
View BVdb publication page



Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Publication Date: 2018

Variant appearance in text: KRAS: K104R
PubMed Link: 29698444
Variant Present in the following documents:
  • pone.0196434.s001.xlsx, sheet 1
  • pone.0196434.s001.xlsx, sheet 3
  • pone.0196434.s001.xlsx, sheet 2
View BVdb publication page



A KRAS GTPase K104Q Mutant Retains Downstream Signaling by Offsetting Defects in Regulation.

The Journal Of Biological Chemistry
Yin, Guowei G; Kistler, Samantha S; George, Samuel D SD; Kuhlmann, Nora N; Garvey, Leslie L; Huynh, Minh M; Bagni, Rachel K RK; Lammers, Michael M; Der, Channing J CJ; Campbell, Sharon L SL
Publication Date: 2017-03-17

Variant appearance in text: KRAS: K104R
PubMed Link: 28154176
Variant Present in the following documents:
  • Main text
View BVdb publication page