KRAS c.283C>A ;(p.H95N)

Variant ID: 12-25380175-G-T

NM_004985.3(KRAS):c.283C>A;(p.H95N)

This variant was identified in 6 publications

View GRCh38 version.




Publications:


Beyond Structural Bioinformatics for Genomics with Dynamics Characterization of an Expanded KRAS Mutational Landscape.

Biorxiv : The Preprint Server For Biology
Ratnasinghe, Brian D BD; Haque, Neshatul N; Wagenknecht, Jessica B JB; Jensen, Davin R DR; Esparza, Guadalupe V GV; Leverence, Elise N EN; De Assuncao, Thiago Milech TM; Mathison, Angela J AJ; Lomberk, Gwen G; Smith, Brian C BC; Volkman, Brian F BF; Urrutia, Raul R; Zimmermann, Michael T MT
Publication Date: 2023-04-28

Variant appearance in text: KRAS: H95N
PubMed Link: 37207265
Variant Present in the following documents:
  • Main text
  • nihpp-2023.04.28.536249v1.pdf
View BVdb publication page



Direct GDP-KRASG12C inhibitors and mechanisms of resistance: the tip of the iceberg.

Therapeutic Advances In Medical Oncology
Rosen, Joshua C JC; Sacher, Adrian A; Tsao, Ming-Sound MS
Publication Date: 2023

Variant appearance in text: KRAS: H95N
PubMed Link: 36950276
Variant Present in the following documents:
  • Main text
  • 10.1177_17588359231160141.pdf
View BVdb publication page



A saturation mutagenesis screen uncovers resistant and sensitizing secondary KRAS mutations to clinical KRASG12C inhibitors.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Feng, Siyu S; Callow, Marinella G MG; Fortin, Jean-Philippe JP; Khan, Zia Z; Bray, David D; Costa, Mike M; Shi, Zhen Z; Wang, Weiru W; Evangelista, Marie M
Publication Date: 2022-05-03

Variant appearance in text: KRAS: H95N
PubMed Link: 35471904
Variant Present in the following documents:
  • pnas.202120512.pdf
  • pnas.2120512119.sapp.pdf
View BVdb publication page



Higher Mutation Burden in High Proliferation Compartments of Heterogeneous Melanoma Tumors.

International Journal Of Molecular Sciences
Grzywa, Tomasz M TM; Koppolu, Agnieszka A AA; Paskal, Wiktor W; Klicka, Klaudia K; Rydzanicz, Małgorzata M; Wejman, Jarosław J; Płoski, Rafał R; Włodarski, Paweł K PK
Publication Date: 2021-04-09

Variant appearance in text: KRAS: 283C>A; His95Asn
PubMed Link: 33918692
Variant Present in the following documents:
  • Main text
View BVdb publication page



Computational Screening and Analysis of Lung Cancer Related Non-Synonymous Single Nucleotide Polymorphisms on the Human Kirsten Rat Sarcoma Gene.

Molecules (Basel, Switzerland)
Wang, Qiankun Q; Mehmood, Aamir A; Wang, Heng H; Xu, Qin Q; Xiong, Yi Y; Wei, Dong-Qing DQ
Publication Date: 2019-05-21

Variant appearance in text: KRAS: H95N; rs1309399018
PubMed Link: 31117243
Variant Present in the following documents:
  • Main text
  • molecules-24-01951.pdf
View BVdb publication page



Resectable lung lesions malignancy assessment and cancer detection by ultra-deep sequencing of targeted gene mutations in plasma cell-free DNA.

Journal Of Medical Genetics
Peng, Muyun M; Xie, Yuancai Y; Li, Xiaohua X; Qian, Youhui Y; Tu, Xiaonian X; Yao, Xumei X; Cheng, Fangsheng F; Xu, Feiyue F; Kong, Deju D; He, Bing B; Liu, Chaoyu C; Cao, Fengjun F; Yang, Haoxian H; Yu, Fenglei F; Xu, Chuanbo C; Tian, Geng G
Publication Date: 2019-10

Variant appearance in text: KRAS: 283C>A; His95Asn
PubMed Link: 30981987
Variant Present in the following documents:
  • jmedgenet-2018-105825supp002.xlsx, sheet 5
View BVdb publication page