KRAS c.274_275delinsCG ;(p.D92R)

Variant ID: 12-25380183-TC-CG

NM_004985.3(KRAS):c.274_275delinsCG;(p.D92R)

This variant was identified in 2 publications

View GRCh38 version.




Publications:


Direct GDP-KRASG12C inhibitors and mechanisms of resistance: the tip of the iceberg.

Therapeutic Advances In Medical Oncology
Rosen, Joshua C JC; Sacher, Adrian A; Tsao, Ming-Sound MS
Publication Date: 2023

Variant appearance in text: KRAS: D92R
PubMed Link: 36950276
Variant Present in the following documents:
  • Main text
  • 10.1177_17588359231160141.pdf
View BVdb publication page



A saturation mutagenesis screen uncovers resistant and sensitizing secondary KRAS mutations to clinical KRASG12C inhibitors.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Feng, Siyu S; Callow, Marinella G MG; Fortin, Jean-Philippe JP; Khan, Zia Z; Bray, David D; Costa, Mike M; Shi, Zhen Z; Wang, Weiru W; Evangelista, Marie M
Publication Date: 2022-05-03

Variant appearance in text: KRAS: D92R
PubMed Link: 35471904
Variant Present in the following documents:
  • pnas.2120512119.sapp.pdf
View BVdb publication page