KRAS c.218G>A ;(p.R73K)

Variant ID: 12-25380240-C-T

NM_004985.3(KRAS):c.218G>A;(p.R73K)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


Defining an embryonal rhabdomyosarcoma endotype.

Cold Spring Harbor Molecular Case Studies
Ricker, Cora A CA; Crawford, Kenneth K; Matlock, Kevin K; Lathara, Melvin M; Seguin, Bernard B; Rudzinski, Erin R ER; Berlow, Noah E NE; Keller, Charles C
Publication Date: 2020-04

Variant appearance in text: KRAS: 218G>A
PubMed Link: 32238403
Variant Present in the following documents:
  • Main text
  • MCS005066Ric.pdf
View BVdb publication page



Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Publication Date: 2018

Variant appearance in text: KRAS: R73K
PubMed Link: 29698444
Variant Present in the following documents:
  • pone.0196434.s001.xlsx, sheet 3
  • pone.0196434.s001.xlsx, sheet 1
  • pone.0196434.s001.xlsx, sheet 2
View BVdb publication page



Oncogenic K-Ras Binds to an Anionic Membrane in Two Distinct Orientations: A Molecular Dynamics Analysis.

Biophysical Journal
Prakash, Priyanka P; Zhou, Yong Y; Liang, Hong H; Hancock, John F JF; Gorfe, Alemayehu A AA
Publication Date: 2016-03-08

Variant appearance in text: K-Ras4B: R73K
PubMed Link: 26958889
Variant Present in the following documents:
  • Main text
View BVdb publication page