Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.
Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Gene mutations in primary tumors and corresponding patient-derived xenografts derived from non-small cell lung cancer.
Cancer Letters
Hao, Chuncheng C; Wang, Li L; Peng, Shaohua S; Cao, Mengru M; Li, Hongyu H; Hu, Jing J; Huang, Xiao X; Liu, Wei W; Zhang, Hui H; Wu, Shuhong S; Pataer, Apar A; Heymach, John V JV; Eterovic, Agda Karina AK; Zhang, Qingxiu Q; Shaw, Kenna R KR; Chen, Ken K; Futreal, Andrew A; Wang, Michael M; Hofstetter, Wayne W; Mehran, Reza R; Rice, David D; Roth, Jack A JA; Sepesi, Boris B; Swisher, Stephen G SG; Vaporciyan, Ara A; Walsh, Garrett L GL; Johnson, Faye M FM; Fang, Bingliang B