KRAS c.205G>A ;(p.D69N)

Variant ID: 12-25380253-C-T

NM_004985.3(KRAS):c.205G>A;(p.D69N)

This variant was identified in 6 publications

View GRCh38 version.




Publications:


Correlation of changes in subclonal architecture with progression in the MMRF CoMMpass study.

Translational Oncology
Kaur, Gurvinder G; Jena, Lingaraja L; Gupta, Ritu R; Farswan, Akanksha A; Gupta, Anubha A; Sriram, K K
Publication Date: 2022-06-28

Variant appearance in text: KRAS: 205G>A; Asp69Asn
PubMed Link: 35777247
Variant Present in the following documents:
  • mmc5.xls, sheet 3
View BVdb publication page



Identification of the nucleotide-free state as a therapeutic vulnerability for inhibition of selected oncogenic RAS mutants.

Cell Reports
Khan, Imran I; Koide, Akiko A; Zuberi, Mariyam M; Ketavarapu, Gayatri G; Denbaum, Eric E; Teng, Kai Wen KW; Rhett, J Matthew JM; Spencer-Smith, Russell R; Hobbs, G Aaron GA; Camp, Ernest Ramsay ER; Koide, Shohei S; O'Bryan, John P JP
Publication Date: 2022-02-08

Variant appearance in text: KRAS: D69N
PubMed Link: 35139380
Variant Present in the following documents:
  • nihms-1778820.pdf
View BVdb publication page



Accurate detection of KRAS, NRAS and BRAF mutations in metastatic colorectal cancers by bridged nucleic acid-clamp real-time PCR.

Bmc Medical Genomics
Nagakubo, Yuki Y; Hirotsu, Yosuke Y; Amemiya, Kenji K; Oyama, Toshio T; Mochizuki, Hitoshi H; Omata, Masao M
Publication Date: 2019-11-11

Variant appearance in text: KRAS: 205G>A
PubMed Link: 31711486
Variant Present in the following documents:
  • 12920_2019_Article_610.pdf
View BVdb publication page



Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Publication Date: 2018

Variant appearance in text: KRAS: D69N
PubMed Link: 29698444
Variant Present in the following documents:
  • pone.0196434.s001.xlsx, sheet 3
  • pone.0196434.s001.xlsx, sheet 2
  • pone.0196434.s001.xlsx, sheet 1
View BVdb publication page



Predicting the functional impact of protein mutations: application to cancer genomics.

Nucleic Acids Research
Reva, Boris B; Antipin, Yevgeniy Y; Sander, Chris C
Publication Date: 2011-09-01

Variant appearance in text: KRAS: D69N
PubMed Link: 21727090
Variant Present in the following documents:
  • supp_gkr407_Supplement2_Table_SM1_COSMIC_mutations.xls, sheet 1
View BVdb publication page



Mutations in epidermal growth factor receptor and K-ras in Chinese patients with colorectal cancer.

Bmc Medical Genetics
Yunxia, Zuo Z; Jun, Cao C; Guanshan, Zhu Z; Yachao, Lu L; Xueke, Zhou Z; Jin, Li L
Publication Date: 2010-02-26

Variant appearance in text: KRAS: Asp69Asn
PubMed Link: 20184776
Variant Present in the following documents:
  • 1471-2350-11-34.pdf
View BVdb publication page