Publications:

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Is adagrasib just another sotorasib?-or, should we differentiate their usage according to patients' clinical presentation?

Translational Lung Cancer Research

Oya, Yuko Y; Mitsudomi, Tetsuya T

Publication Date: 2023-05-31

Variant appearance in text: KRAS: R68M

PubMed Link: 37323182

Variant Present in the following documents:

• Main text
• tlcr-12-05-940.pdf

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Recent Advances in Covalent Drug Discovery.

Pharmaceuticals (Basel, Switzerland)

Schaefer, Daniel D; Cheng, Xinlai X

Publication Date: 2023-04-28

Variant appearance in text: KRAS: R68M

PubMed Link: 37242447

Variant Present in the following documents:

• Main text
• pharmaceuticals-16-00663.pdf

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Direct GDP-KRASG12C inhibitors and mechanisms of resistance: the tip of the iceberg.

Therapeutic Advances In Medical Oncology

Rosen, Joshua C JC; Sacher, Adrian A; Tsao, Ming-Sound MS

Publication Date: 2023

Variant appearance in text: KRAS: R68M

PubMed Link: 36950276

Variant Present in the following documents:

• Main text
• 10.1177_17588359231160141.pdf

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Targeted therapies for KRAS-mutant non-small cell lung cancer: from preclinical studies to clinical development-a narrative review.

Translational Lung Cancer Research

Santarpia, Mariacarmela M; Ciappina, Giuliana G; Spagnolo, Calogera Claudia CC; Squeri, Andrea A; Passalacqua, Maria Ilenia MI; Aguilar, Andrés A; Gonzalez-Cao, Maria M; Giovannetti, Elisa E; Silvestris, Nicola N; Rosell, Rafael R

Publication Date: 2023-02-28

Variant appearance in text: KRAS: R68M

PubMed Link: 36895930

Variant Present in the following documents:

• Main text
• tlcr-12-02-346.pdf

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Circulating tumour DNA analysis predicts relapse and improves risk stratification in primary refractory multiple myeloma.

Blood Cancer Journal

Mithraprabhu, Sridurga S; Reynolds, John J; Turner, Rose R; Quach, Hang H; Horvath, Noemi N; Kerridge, Ian I; Kalff, Anna A; Bergin, Krystal K; Hocking, Jay J; Yuen, Flora F; Khong, Tiffany T; Durie, Brian M BM; Spencer, Andrew A

Publication Date: 2023-02-13

Variant appearance in text: KRAS: 203G>T; R68M

PubMed Link: 36781844

Variant Present in the following documents:

• 41408_2023_796_MOESM2_ESM.xlsx, sheet 1

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KRAS Mutations in Solid Tumors: Characteristics, Current Therapeutic Strategy, and Potential Treatment Exploration.

Journal Of Clinical Medicine

Yang, Yunkai Y; Zhang, Huan H; Huang, Shanshan S; Chu, Qian Q

Publication Date: 2023-01-16

Variant appearance in text: KRAS: R68M

PubMed Link: 36675641

Variant Present in the following documents:

• Main text
• jcm-12-00709.pdf

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Targeting KRAS G12C mutations in colorectal cancer.

Gastroenterology Report

Zhao, Ming-He MH; Wu, Ai-Wen AW

Publication Date: 2023

Variant appearance in text: KRAS: R68M

PubMed Link: 36632627

Variant Present in the following documents:

• Main text
• goac083.pdf

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How to manage KRAS G12C-mutated advanced non-small-cell lung cancer.

Drugs In Context

Ricciuti, Biagio B; Mira, Alessia A; Andrini, Elisa E; Scaparone, Pietro P; Michelina, Sandra Vietti SV; Pecci, Federica F; Cantini, Luca L; De Giglio, Andrea A; Lamberti, Giuseppe G; Ambrogio, Chiara C; Metro, Giulio G

Publication Date: 2022

Variant appearance in text: KRAS: R68M

PubMed Link: 36452878

Variant Present in the following documents:

• Main text
• dic-2022-7-4.pdf

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A sex-informed approach to improve the personalised decision making process in myelodysplastic syndromes: a multicentre, observational cohort study.

The Lancet. Haematology

,

Publication Date: 2022-11-24

Variant appearance in text: KRAS: 203G>T; R68M

PubMed Link: 36436542

Variant Present in the following documents:

• mmc2.xlsx, sheet 1

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Somatic mutation distribution across tumour cohorts provides a signal for positive selection in cancer.

Nature Communications

Boström, Martin M; Larsson, Erik E

Publication Date: 2022-11-17

Variant appearance in text: KRAS: R68M

PubMed Link: 36396655

Variant Present in the following documents:

• 41467_2022_34746_MOESM10_ESM.xlsx, sheet 1

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Molecular Biology and Therapeutic Perspectives for K-Ras Mutant Non-Small Cell Lung Cancers.

Cancers

Cekani, Elona E; Epistolio, Samantha S; Dazio, Giulia G; Cefalì, Marco M; Wannesson, Luciano L; Frattini, Milo M; Froesch, Patrizia P

Publication Date: 2022-08-24

Variant appearance in text: KRAS: 203G>T; R68M

PubMed Link: 36077640

Variant Present in the following documents:

• Main text
• cancers-14-04103.pdf

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The current state of the art and future trends in RAS-targeted cancer therapies.

Nature Reviews. Clinical Oncology

Punekar, Salman R SR; Velcheti, Vamsidhar V; Neel, Benjamin G BG; Wong, Kwok-Kin KK

Publication Date: 2022-10

Variant appearance in text: KRAS: R68M

PubMed Link: 36028717

Variant Present in the following documents:

• Main text
• 41571_2022_Article_671.pdf

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Conquering oncogenic KRAS and its bypass mechanisms.

Theranostics

Hou, Pingping P; Wang, Y Alan YA

Publication Date: 2022

Variant appearance in text: KRAS: R68M

PubMed Link: 35966590

Variant Present in the following documents:

• Main text
• thnov12p5691.pdf

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Molecular evolutionary process of advanced gastric cancer during sequential chemotherapy detected by circulating tumor DNA.

Journal Of Translational Medicine

Xi, Wenqi W; Zhou, Chenfei C; Xu, Fei F; Sun, Debin D; Wang, Shengzhou S; Chen, Yawei Y; Ji, Jun J; Ma, Tao T; Wu, Junwei J; Shangguan, Chengfang C; Zhu, Zhenggang Z; Zhang, Jun J

Publication Date: 2022-08-12

Variant appearance in text: KRAS: 203G>T; R68M

PubMed Link: 35962408

Variant Present in the following documents:

• 12967_2022_3567_MOESM9_ESM.xlsx, sheet 1

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Targeting KRAS G12C-Mutated Advanced Colorectal Cancer: Research and Clinical Developments.

Oncotargets And Therapy

Ji, Jingran J; Wang, Chongkai C; Fakih, Marwan M

Publication Date: 2022

Variant appearance in text: KRAS: R68M

PubMed Link: 35837349

Variant Present in the following documents:

• Main text
• ott-15-747.pdf

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Targeting KRAS Mutant in Non-Small Cell Lung Cancer: Novel Insights Into Therapeutic Strategies.

Frontiers In Oncology

Désage, Anne-Laure AL; Léonce, Camille C; Swalduz, Aurélie A; Ortiz-Cuaran, Sandra S

Publication Date: 2022

Variant appearance in text: KRAS: R68M

PubMed Link: 35251972

Variant Present in the following documents:

• Main text
• fonc-12-796832.pdf

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Targeting KRAS in Non-Small Cell Lung Cancer.

Frontiers In Oncology

Corral de la Fuente, Elena E; Olmedo Garcia, Maria Eugenia ME; Gomez Rueda, Ana A; Lage, Yolanda Y; Garrido, Pilar P

Publication Date: 2021

Variant appearance in text: KRAS: R68M

PubMed Link: 35083149

Variant Present in the following documents:

• Main text
• fonc-11-792635.pdf

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A Breakthrough Brought about by Targeting KRASG12C: Nonconformity Is Punished.

Cancers

Ning, Wenjuan W; Yang, Zhang Z; Kocher, Gregor J GJ; Dorn, Patrick P; Peng, Ren-Wang RW

Publication Date: 2022-01-13

Variant appearance in text: KRAS: R68M

PubMed Link: 35053550

Variant Present in the following documents:

• Main text

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A Breakthrough Brought about by Targeting KRASG12C: Nonconformity Is Punished.

Cancers

Ning, Wenjuan W; Yang, Zhang Z; Kocher, Gregor J GJ; Dorn, Patrick P; Peng, Ren-Wang RW

Publication Date: 2022-01-13

Variant appearance in text: KRAS: R68M

PubMed Link: 35053550

Variant Present in the following documents:

• Main text

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Resistance to KRASG12C Inhibitors in Non-Small Cell Lung Cancer.

Frontiers In Oncology

Blaquier, Juan Bautista JB; Cardona, Andrés Felipe AF; Recondo, Gonzalo G

Publication Date: 2021

Variant appearance in text: KRAS: R68M

PubMed Link: 35004309

Variant Present in the following documents:

• Main text
• fonc-11-787585.pdf

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Targeting Oncogenic KRAS in Non-Small-Cell Lung Cancer.

Cancers

Sunaga, Noriaki N; Miura, Yosuke Y; Kasahara, Norimitsu N; Sakurai, Reiko R

Publication Date: 2021-11-26

Variant appearance in text: KRAS: R68M

PubMed Link: 34885068

Variant Present in the following documents:

• Main text
• cancers-13-05956.pdf

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Targeting Oncogenic KRAS in Non-Small-Cell Lung Cancer.

Cancers

Sunaga, Noriaki N; Miura, Yosuke Y; Kasahara, Norimitsu N; Sakurai, Reiko R

Publication Date: 2021-11-26

Variant appearance in text: KRAS: R68M

PubMed Link: 34885068

Variant Present in the following documents:

• Main text
• cancers-13-05956.pdf

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KRAS mutation: from undruggable to druggable in cancer.

Signal Transduction And Targeted Therapy

Huang, Lamei L; Guo, Zhixing Z; Wang, Fang F; Fu, Liwu L

Publication Date: 2021-11-15

Variant appearance in text: KRAS: R68M

PubMed Link: 34776511

Variant Present in the following documents:

• Main text
• 41392_2021_Article_780.pdf

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Spotlight on Sotorasib (AMG 510) for KRAS G12C Positive Non-Small Cell Lung Cancer.

Lung Cancer (Auckland, N.Z.)

Zhang, Shannon S SS; Nagasaka, Misako M

Publication Date: 2021

Variant appearance in text: KRAS: R68M

PubMed Link: 34675734

Variant Present in the following documents:

• Main text

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KRAS G12C Mutations in NSCLC: From Target to Resistance.

Cancers

Addeo, Alfredo A; Banna, Giuseppe Luigi GL; Friedlaender, Alex A

Publication Date: 2021-05-21

Variant appearance in text: KRAS: R68M

PubMed Link: 34064232

Variant Present in the following documents:

• Main text
• cancers-13-02541.pdf

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Spatially interacting phosphorylation sites and mutations in cancer.

Nature Communications

Huang, Kuan-Lin KL; Scott, Adam D AD; Zhou, Daniel Cui DC; Wang, Liang-Bo LB; Weerasinghe, Amila A; Elmas, Abdulkadir A; Liu, Ruiyang R; Wu, Yige Y; Wendl, Michael C MC; Wyczalkowski, Matthew A MA; Baral, Jessika J; Sengupta, Sohini S; Lai, Chin-Wen CW; Ruggles, Kelly K; Payne, Samuel H SH; Raphael, Benjamin B; Fenyö, David D; Chen, Ken K; Mills, Gordon G; Ding, Li L

Publication Date: 2021-04-19

Variant appearance in text: KRAS: R68M

PubMed Link: 33875650

Variant Present in the following documents:

• 41467_2021_22481_MOESM4_ESM.xlsx, sheet 1
• 41467_2021_22481_MOESM4_ESM.xlsx, sheet 6

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mTOR Signaling and SREBP Activity Increase FADS2 Expression and Can Activate Sapienate Biosynthesis.

Cell Reports

Triki, Mouna M; Rinaldi, Gianmarco G; Planque, Melanie M; Broekaert, Dorien D; Winkelkotte, Alina M AM; Maier, Carina R CR; Janaki Raman, Sudha S; Vandekeere, Anke A; Van Elsen, Joke J; Orth, Martin F MF; Grünewald, Thomas G P TGP; Schulze, Almut A; Fendt, Sarah-Maria SM

Publication Date: 2020-06-23

Variant appearance in text: KRAS: R68M

PubMed Link: 32579932

Variant Present in the following documents:

• mmc5.xlsx, sheet 3

View BVdb publication page

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NOTCH target gene HES5 mediates oncogenic and tumor suppressive functions in hepatocarcinogenesis.

Oncogene

Luiken, Sarah S; Fraas, Angelika A; Bieg, Matthias M; Sugiyanto, Raisatun R; Goeppert, Benjamin B; Singer, Stephan S; Ploeger, Carolin C; Warsow, Gregor G; Marquardt, Jens U JU; Sticht, Carsten C; De La Torre, Carolina C; Pusch, Stefan S; Mehrabi, Arianeb A; Gretz, Norbert N; Schlesner, Matthias M; Eils, Roland R; Schirmacher, Peter P; Longerich, Thomas T; Roessler, Stephanie S

Publication Date: 2020-04

Variant appearance in text: KRAS: 203G>T; Arg68Met

PubMed Link: 32055024

Variant Present in the following documents:

• 41388_2020_1198_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Nature Communications

Kis, Olena O; Kaedbey, Rayan R; Chow, Signy S; Danesh, Arnavaz A; Dowar, Mark M; Li, Tiantian T; Li, Zhihua Z; Liu, Jessica J; Mansour, Mark M; Masih-Khan, Esther E; Zhang, Tong T; Bratman, Scott V SV; Oza, Amit M AM; Kamel-Reid, Suzanne S; Trudel, Suzanne S; Pugh, Trevor J TJ

Publication Date: 2017-05-11

Variant appearance in text: KRAS: 203G>T

PubMed Link: 28492226

Variant Present in the following documents:

• ncomms15086-s3.xlsx, sheet 1

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LowMACA: exploiting protein family analysis for the identification of rare driver mutations in cancer.

Bmc Bioinformatics

Melloni, Giorgio E M GE; de Pretis, Stefano S; Riva, Laura L; Pelizzola, Mattia M; Céol, Arnaud A; Costanza, Jole J; Müller, Heiko H; Zammataro, Luca L

Publication Date: 2016-02-09

Variant appearance in text: KRAS: R68M

PubMed Link: 26860319

Variant Present in the following documents:

• 12859_2016_935_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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