KRAS c.176_177delinsAC ;(p.A59D)

Variant ID: 12-25380281-TG-GT

NM_004985.3(KRAS):c.176_177delinsAC;(p.A59D)

This variant was identified in 6 publications

View GRCh38 version.




Publications:


Whole-transcriptome analysis in acute lymphoblastic leukemia: a report from the DFCI ALL Consortium Protocol 16-001.

Blood Advances
Tran, Thai Hoa TH; Langlois, Sylvie S; Meloche, Caroline C; Caron, Maxime M; Saint-Onge, Pascal P; Rouette, Alexandre A; Bataille, Alain R AR; Jimenez-Cortes, Camille C; Sontag, Thomas T; Bittencourt, Henrique H; Laverdière, Caroline C; Lavallée, Vincent-Philippe VP; Leclerc, Jean-Marie JM; Cole, Peter D PD; Gennarini, Lisa M LM; Kahn, Justine M JM; Kelly, Kara M KM; Michon, Bruno B; Santiago, Raoul R; Stevenson, Kristen E KE; Welch, Jennifer J G JJG; Schroeder, Kaitlin M KM; Koch, Victoria V; Cellot, Sonia S; Silverman, Lewis B LB; Sinnett, Daniel D
Publication Date: 2022-02-22

Variant appearance in text: KRAS: A59D
PubMed Link: 34933343
Variant Present in the following documents:
  • advancesADV2021005634-suppl1.xlsx, sheet 1
View BVdb publication page



The genomic landscape of carcinomas with mucinous differentiation.

Scientific Reports
Nguyen, Bastien B; Sanchez-Vega, Francisco F; Fong, Christopher J CJ; Chatila, Walid K WK; Boroujeni, Amir Momeni AM; Pareja, Fresia F; Weigelt, Britta B; Sotiriou, Christos C; Larsimont, Denis D; Reis-Filho, Jorge S JS; Desmedt, Christine C; Schultz, Nikolaus N
Publication Date: 2021-05-04

Variant appearance in text: KRAS: A59D
PubMed Link: 33947930
Variant Present in the following documents:
  • Main text
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EZH2 inactivation in RAS-driven myeloid neoplasms hyperactivates RAS-signaling and increases MEK inhibitor sensitivity.

Leukemia
Berg, Johannes Lorenz JL; Perfler, Bianca B; Hatzl, Stefan S; Uhl, Barbara B; Reinisch, Andreas A; Pregartner, Gudrun G; Berghold, Andrea A; Penz, Thomas T; Schuster, Michael M; Geissler, Klaus K; Prokesch, Andreas A; Müller-Tidow, Carsten C; Hoefler, Gerald G; Kashofer, Karl K; Wölfler, Albert A; Sill, Heinz H; Caraffini, Veronica V; Zebisch, Armin A
Publication Date: 2021-05

Variant appearance in text: KRAS: A59D
PubMed Link: 33589750
Variant Present in the following documents:
  • 41375_2021_1161_MOESM1_ESM.pdf
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EGFR inhibition triggers an adaptive response by co-opting antiviral signaling pathways in lung cancer.

Nature Cancer
Gong, Ke K; Guo, Gao G; Panchani, Nishah N; Bender, Matthew E ME; Gerber, David E DE; Minna, John D JD; Fattah, Farjana F; Gao, Boning B; Peyton, Michael M; Kernstine, Kemp K; Mukherjee, Bipasha B; Burma, Sandeep S; Chiang, Cheng-Ming CM; Zhang, Shanrong S; Sathe, Adwait Amod AA; Xing, Chao C; Dao, Kathryn H KH; Zhao, Dawen D; Akbay, Esra A EA; Habib, Amyn A AA
Publication Date: 2020-04

Variant appearance in text: KRAS: A59D
PubMed Link: 33269343
Variant Present in the following documents:
  • Main text
View BVdb publication page



A Spontaneous Aggressive ERα+ Mammary Tumor Model Is Driven by Kras Activation.

Cell Reports
Campbell, Katie M KM; O'Leary, Kathleen A KA; Rugowski, Debra E DE; Mulligan, William A WA; Barnell, Erica K EK; Skidmore, Zachary L ZL; Krysiak, Kilannin K; Griffith, Malachi M; Schuler, Linda A LA; Griffith, Obi L OL
Publication Date: 2019-08-06

Variant appearance in text: KRAS: A59D
PubMed Link: 31390566
Variant Present in the following documents:
  • Main text
View BVdb publication page



Prospective study of a molecular selection profile for RAS wild type colorectal cancer patients receiving irinotecan-cetuximab.

Journal Of Translational Medicine
Giampieri, Riccardo R; Mandolesi, Alessandra A; Abouelkhair, Khaled M KM; Loretelli, Cristian C; Del Prete, Michela M; Faloppi, Luca L; Maristella, Bianconi B; Ibrahim, Ezzeldin M EM; Scarpelli, Marina M; Cascinu, Stefano S; Scartozzi, Mario M
Publication Date: 2015-05-07

Variant appearance in text: KRAS: A59D
PubMed Link: 25943333
Variant Present in the following documents:
  • Main text
  • 12967_2015_Article_501.pdf
View BVdb publication page