KRAS c.175_176delinsAA ;(p.A59K)

Variant ID: 12-25380282-GC-TT

NM_004985.3(KRAS):c.175_176delinsAA;(p.A59K)

This variant was identified in 8 publications

View GRCh38 version.




Publications:


Typical tumor immune microenvironment status determine prognosis in lung adenocarcinoma.

Translational Oncology
Ren, Caixia C; Li, Jinyu J; Zhou, Yang Y; Zhang, Shuyu S; Wang, Qi Q
Publication Date: 2022-04

Variant appearance in text: KRAS: A59K
PubMed Link: 35176624
Variant Present in the following documents:
  • mmc2.xlsx, sheet 9
View BVdb publication page



A chemoresistance lncRNA signature for recurrence risk stratification of colon cancer patients with chemotherapy.

Molecular Therapy. Nucleic Acids
Wang, Hao H; Gao, Yuzhen Y; Vafaei, Somayeh S; Yu, Qiaoyan Q; Zhang, Jun J; Wang, Liangjing L
Publication Date: 2022-03-08

Variant appearance in text: KRAS: A59K
PubMed Link: 35036055
Variant Present in the following documents:
  • mmc2.pdf
View BVdb publication page



Proteogenomics of non-small cell lung cancer reveals molecular subtypes associated with specific therapeutic targets and immune evasion mechanisms.

Nature Cancer
Lehtiö, Janne J; Arslan, Taner T; Siavelis, Ioannis I; Pan, Yanbo Y; Socciarelli, Fabio F; Berkovska, Olena O; Umer, Husen M HM; Mermelekas, Georgios G; Pirmoradian, Mohammad M; Jönsson, Mats M; Brunnström, Hans H; Brustugun, Odd Terje OT; Purohit, Krishna Pinganksha KP; Cunningham, Richard R; Foroughi Asl, Hassan H; Isaksson, Sofi S; Arbajian, Elsa E; Aine, Mattias M; Karlsson, Anna A; Kotevska, Marija M; Gram Hansen, Carsten C; Drageset Haakensen, Vilde V; Helland, Åslaug Å; Tamborero, David D; Johansson, Henrik J HJ; Branca, Rui M RM; Planck, Maria M; Staaf, Johan J; Orre, Lukas M LM
Publication Date: 2021-11

Variant appearance in text: KRAS: A59K
PubMed Link: 34870237
Variant Present in the following documents:
  • EMS133264-supplement-Source_Data_to_Extended_Data_Fig_9.xlsx, sheet 1
View BVdb publication page



Construction and validation of a 15-gene ferroptosis signature in lung adenocarcinoma.

Peerj
Tu, Guangxu G; Peng, Weilin W; Cai, Qidong Q; Zhao, Zhenyu Z; Peng, Xiong X; He, Boxue B; Zhang, Pengfei P; Shi, Shuai S; Tao, Yongguang Y; Wang, Xiang X
Publication Date: 2021

Variant appearance in text: KRAS: A59K
PubMed Link: 34277151
Variant Present in the following documents:
  • peerj-09-11687-s004.xlsx, sheet 1
View BVdb publication page



A KRAS-responsive long non-coding RNA controls microRNA processing.

Nature Communications
Shi, Lei L; Magee, Peter P; Fassan, Matteo M; Sahoo, Sudhakar S; Leong, Hui Sun HS; Lee, Dave D; Sellers, Robert R; Brullé-Soumaré, Laura L; Cairo, Stefano S; Monteverde, Tiziana T; Volinia, Stefano S; Smith, Duncan D DD; Di Leva, Gianpiero G; Galuppini, Francesca F; Paliouras, Athanasios R AR; Zeng, Kang K; O'Keefe, Raymond R; Garofalo, Michela M
Publication Date: 2021-04-01

Variant appearance in text: KRAS: A59K
PubMed Link: 33795683
Variant Present in the following documents:
  • 41467_2021_22337_MOESM4_ESM.xlsx, sheet 1
View BVdb publication page



Enhancer remodeling promotes tumor-initiating activity in NRF2-activated non-small cell lung cancers.

Nature Communications
Okazaki, Keito K; Anzawa, Hayato H; Liu, Zun Z; Ota, Nao N; Kitamura, Hiroshi H; Onodera, Yoshiaki Y; Alam, Md Morshedul MM; Matsumaru, Daisuke D; Suzuki, Takuma T; Katsuoka, Fumiki F; Tadaka, Shu S; Motoike, Ikuko I; Watanabe, Mika M; Hayasaka, Kazuki K; Sakurada, Akira A; Okada, Yoshinori Y; Yamamoto, Masayuki M; Suzuki, Takashi T; Kinoshita, Kengo K; Sekine, Hiroki H; Motohashi, Hozumi H
Publication Date: 2020-11-20

Variant appearance in text: KRAS: A59K
PubMed Link: 33219226
Variant Present in the following documents:
  • 41467_2020_19593_MOESM4_ESM.xlsx, sheet 8
View BVdb publication page



Inactivation of tumor suppressor gene Clusterin leads to hyperactivation of TAK1-NF-κB signaling axis in lung cancer cells and denotes a therapeutic opportunity.

Theranostics
Chen, Zhipeng Z; Fan, Zhenzhen Z; Dou, Xiaowei X; Zhou, Qian Q; Zeng, Guandi G; Liu, Lu L; Chen, Wensheng W; Lan, Ruirui R; Liu, Wanting W; Ru, Guoqing G; Yu, Lei L; He, Qing-Yu QY; Chen, Liang L
Publication Date: 2020

Variant appearance in text: KRAS: A59K
PubMed Link: 33052230
Variant Present in the following documents:
  • thnov10p11520s2.xlsx, sheet 1
View BVdb publication page



Identification of a novel prognostic DNA methylation signature for lung adenocarcinoma based on consensus clustering method.

Cancer Medicine
Cai, Qidong Q; He, Boxue B; Xie, Hui H; Zhang, Pengfei P; Peng, Xiong X; Zhang, Yuqian Y; Zhao, Zhenyu Z; Wang, Xiang X
Publication Date: 2020-10

Variant appearance in text: KRAS: A59K
PubMed Link: 32860318
Variant Present in the following documents:
  • CAM4-9-7488-s009.xlsx, sheet 1
View BVdb publication page