Molecular Neuropathology in Practice: Clinical Profiling and Integrative Analysis of Molecular Alterations in Glioblastoma.
Academic Pathology
Nasrallah, MacLean P MP; Binder, Zev A ZA; Oldridge, Derek A DA; Zhao, Jianhua J; Lieberman, David B DB; Roth, Jacquelyn J JJ; Watt, Christopher D CD; Sukhadia, Shrey S; Klinman, Eva E; Daber, Robert D RD; Desai, Arati A; Brem, Steven S; O'Rourke, Donald M DM; Morrissette, Jennifer J D JJD
Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.
Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Mutational landscape reflects the biological continuum of plasma cell dyscrasias.
Blood Cancer Journal
Rossi, A A; Voigtlaender, M M; Janjetovic, S S; Thiele, B B; Alawi, M M; März, M M; Brandt, A A; Hansen, T T; Radloff, J J; Schön, G G; Hegenbart, U U; Schönland, S S; Langer, C C; Bokemeyer, C C; Binder, M M
Clinical applicability and cost of a 46-gene panel for genomic analysis of solid tumours: Retrospective validation and prospective audit in the UK National Health Service.
Plos Medicine
Hamblin, Angela A; Wordsworth, Sarah S; Fermont, Jilles M JM; Page, Suzanne S; Kaur, Kulvinder K; Camps, Carme C; Kaisaki, Pamela P; Gupta, Avinash A; Talbot, Denis D; Middleton, Mark M; Henderson, Shirley S; Cutts, Anthony A; Vavoulis, Dimitrios V DV; Housby, Nick N; Tomlinson, Ian I; Taylor, Jenny C JC; Schuh, Anna A
Spatio-temporal mutation profiles of case-matched colorectal carcinomas and their metastases reveal unique de novo mutations in metachronous lung metastases by targeted next generation sequencing.
Molecular Cancer
Kovaleva, Valentina V; Geissler, Anna-Lena AL; Lutz, Lisa L; Fritsch, Ralph R; Makowiec, Frank F; Wiesemann, Sebastian S; Hopt, Ulrich T UT; Passlick, Bernward B; Werner, Martin M; Lassmann, Silke S
Publication Date: 2016-10-18
Variant appearance in text: KRAS: 145G>A; Glu49Lys
Prognostic role of KRAS mutations in Sardinian patients with colorectal carcinoma.
Oncology Letters
Palomba, Grazia G; Cossu, Antonio A; Paliogiannis, Panagiotis P; Pazzola, Antonio A; Baldino, Giovanni G; Scartozzi, Mario M; Ionta, Maria Teresa MT; Ortu, Salvatore S; Capelli, Francesca F; Lanzillo, Annamaria A; Sedda, Tito T; Sanna, Giovanni G; Barca, Michela M; Virdis, Luciano L; Budroni, Mario M; Palmieri, Giuseppe G
mutation3D: Cancer Gene Prediction Through Atomic Clustering of Coding Variants in the Structural Proteome.
Human Mutation
Meyer, Michael J MJ; Lapcevic, Ryan R; Romero, Alfonso E AE; Yoon, Mark M; Das, Jishnu J; Beltrán, Juan Felipe JF; Mort, Matthew M; Stenson, Peter D PD; Cooper, David N DN; Paccanaro, Alberto A; Yu, Haiyuan H
Assessing the clinical value of targeted massively parallel sequencing in a longitudinal, prospective population-based study of cancer patients.
British Journal Of Cancer
Wong, S Q SQ; Fellowes, A A; Doig, K K; Ellul, J J; Bosma, T J TJ; Irwin, D D; Vedururu, R R; Tan, A Y-C AY; Weiss, J J; Chan, K S KS; Lucas, M M; Thomas, D M DM; Dobrovic, A A; Parisot, J P JP; Fox, S B SB
Publication Date: 2015-04-14
Variant appearance in text: KRAS: 145G>A; Glu49Lys
High resolution melting analysis of KRAS, BRAF and PIK3CA in KRAS exon 2 wild-type metastatic colorectal cancer.
Bmc Cancer
Guedes, Joana G JG; Veiga, Isabel I; Rocha, Patrícia P; Pinto, Pedro P; Pinto, Carla C; Pinheiro, Manuela M; Peixoto, Ana A; Fragoso, Maria M; Raimundo, Ana A; Ferreira, Paula P; Machado, Manuela M; Sousa, Nuno N; Lopes, Paula P; Araújo, António A; Macedo, Joana J; Alves, Fernando F; Coutinho, Camila C; Henrique, Rui R; Santos, Lúcio L LL; Teixeira, Manuel R MR
Publication Date: 2013-04-01
Variant appearance in text: KRAS: 145G>A; Glu49Lys
Prevalence of KRAS, BRAF, and PIK3CA somatic mutations in patients with colorectal carcinoma may vary in the same population: clues from Sardinia.
Journal Of Translational Medicine
Palomba, Grazia G; Colombino, Maria M; Contu, Antonio A; Massidda, Bruno B; Baldino, Giovanni G; Pazzola, Antonio A; Ionta, MariaTeresa M; Capelli, Francesca F; Trova, Vittorio V; Sedda, Tito T; Sanna, Giovanni G; Tanda, Francesco F; Budroni, Mario M; , ; Palmieri, Giuseppe G; Cossu, Antonio A; Contu, Marta M; Cuccu, Angelo A; Farris, Antonio A; Macciò, Antonio A; Mameli, Giuseppe G; Olmeo, Nina N; Ortu, Salvatore S; Petretto, Elisabetta E; Pusceddu, Valeria V; Virdis, Luciano L