KRAS c.127_128delinsGC ;(p.Q43A)

Variant ID: 12-25380330-TG-GC

NM_004985.3(KRAS):c.127_128delinsGC;(p.Q43A)

This variant was identified in 2 publications

View GRCh38 version.




Publications:


AIMP2-DX2 provides therapeutic interface to control KRAS-driven tumorigenesis.

Nature Communications
Kim, Dae Gyu DG; Choi, Yongseok Y; Lee, Yuno Y; Lim, Semi S; Kong, Jiwon J; Song, JaeHa J; Roh, Younah Y; Harmalkar, Dipesh S DS; Lee, Kwanshik K; Goo, Ja-Il JI; Cho, Hye Young HY; Mushtaq, Ameeq Ul AU; Lee, Jihye J; Park, Song Hwa SH; Kim, Doyeun D; Min, Byung Soh BS; Lee, Kang Young KY; Jeon, Young Ho YH; Lee, Sunkyung S; Lee, Kyeong K; Kim, Sunghoon S
Publication Date: 2022-05-11

Variant appearance in text: KRAS: Q43A
PubMed Link: 35546148
Variant Present in the following documents:
  • 41467_2022_30149_MOESM1_ESM.pdf
View BVdb publication page



KRAS interaction with RAF1 RAS-binding domain and cysteine-rich domain provides insights into RAS-mediated RAF activation.

Nature Communications
Tran, Timothy H TH; Chan, Albert H AH; Young, Lucy C LC; Bindu, Lakshman L; Neale, Chris C; Messing, Simon S; Dharmaiah, Srisathiyanarayanan S; Taylor, Troy T; Denson, John-Paul JP; Esposito, Dominic D; Nissley, Dwight V DV; Stephen, Andrew G AG; McCormick, Frank F; Simanshu, Dhirendra K DK
Publication Date: 2021-02-19

Variant appearance in text: KRAS: Q43A
PubMed Link: 33608534
Variant Present in the following documents:
  • Main text
  • 41467_2021_21422_MOESM4_ESM.xlsx, sheet 7
  • 41467_2021_Article_21422.pdf
  • 41467_2021_21422_MOESM1_ESM.pdf
  • 41467_2021_21422_MOESM4_ESM.xlsx, sheet 4
View BVdb publication page