Publications:

Landscape of somatic single nucleotide variants and indels in colorectal cancer and impact on survival.

Nature Communications

Zaidi, Syed H SH; Harrison, Tabitha A TA; Phipps, Amanda I AI; Steinfelder, Robert R; Trinh, Quang M QM; Qu, Conghui C; Banbury, Barbara L BL; Georgeson, Peter P; Grasso, Catherine S CS; Giannakis, Marios M; Adams, Jeremy B JB; Alwers, Elizabeth E; Amitay, Efrat L EL; Barfield, Richard T RT; Berndt, Sonja I SI; Borozan, Ivan I; Brenner, Hermann H; Brezina, Stefanie S; Buchanan, Daniel D DD; Cao, Yin Y; Chan, Andrew T AT; Chang-Claude, Jenny J; Connolly, Charles M CM; Drew, David A DA; Farris, Alton Brad AB; Figueiredo, Jane C JC; French, Amy J AJ; Fuchs, Charles S CS; Garraway, Levi A LA; Gruber, Steve S; Guinter, Mark A MA; Hamilton, Stanley R SR; Harlid, Sophia S; Heisler, Lawrence E LE; Hidaka, Akihisa A; Hopper, John L JL; Huang, Wen-Yi WY; Huyghe, Jeroen R JR; Jenkins, Mark A MA; Krzyzanowski, Paul M PM; Lemire, Mathieu M; Lin, Yi Y; Luo, Xuemei X; Mardis, Elaine R ER; McPherson, John D JD; Miller, Jessica K JK; Moreno, Victor V; Mu, Xinmeng Jasmine XJ; Nishihara, Reiko R; Papadopoulos, Nickolas N; Pasternack, Danielle D; Quist, Michael J MJ; Rafikova, Adilya A; Reid, Emma E G EEG; Shinbrot, Eve E; Shirts, Brian H BH; Stein, Lincoln D LD; Teney, Cherie D CD; Timms, Lee L; Um, Caroline Y CY; Van Guelpen, Bethany B; Van Tassel, Megan M; Wang, Xiaolong X; Wheeler, David A DA; Yung, Christina K CK; Hsu, Li L; Ogino, Shuji S; Gsur, Andrea A; Newcomb, Polly A PA; Gallinger, Steven S; Hoffmeister, Michael M; Campbell, Peter T PT; Thibodeau, Stephen N SN; Sun, Wei W; Hudson, Thomas J TJ; Peters, Ulrike U

Publication Date: 2020-07-20

Variant appearance in text: KRAS: D38E

PubMed Link: 32686686

Variant Present in the following documents:

• 41467_2020_17386_MOESM4_ESM.xlsx, sheet 1

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Autoinhibition in Ras effectors Raf, PI3Kα, and RASSF5: a comprehensive review underscoring the challenges in pharmacological intervention.

Biophysical Reviews

Nussinov, Ruth R; Zhang, Mingzhen M; Tsai, Chung-Jung CJ; Liao, Tsung-Jen TJ; Fushman, David D; Jang, Hyunbum H

Publication Date: 2018-10

Variant appearance in text: KRAS: D38E

PubMed Link: 30269291

Variant Present in the following documents:

• Main text

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Ras effector mutant expression suggest a negative regulator inhibits lung tumor formation.

Plos One

Vandal, Guillaume G; Geiling, Benjamin B; Dankort, David D

Publication Date: 2014

Variant appearance in text: KRAS: D38E

PubMed Link: 24489653

Variant Present in the following documents:

• Main text
• pone.0084745.pdf

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Genetic analysis of Ras signalling pathways in cell proliferation, migration and survival.

The Embo Journal

Drosten, Matthias M; Dhawahir, Alma A; Sum, Eleanor Y M EY; Urosevic, Jelena J; Lechuga, Carmen G CG; Esteban, Luis M LM; Castellano, Esther E; Guerra, Carmen C; Santos, Eugenio E; Barbacid, Mariano M

Publication Date: 2010-03-17

Variant appearance in text: K-Ras4B: D38E

PubMed Link: 20150892

Variant Present in the following documents:

• Main text

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Activated Ras induces cytoplasmic vacuolation and non-apoptotic death in glioblastoma cells via novel effector pathways.

Cellular Signalling

Kaul, Aparna A; Overmeyer, Jean H JH; Maltese, William A WA

Publication Date: 2007-05

Variant appearance in text: K-Ras4B: D38E

PubMed Link: 17210246

Variant Present in the following documents:

• Main text

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