Publications:

Covalent inhibitor targets KRasG12C: A new paradigm for drugging the undruggable and challenges ahead.

Genes & Diseases

Li, Hui-Yu HY; Qi, Wei-Liang WL; Wang, Yu-Xiang YX; Meng, Ling-Hua LH

Publication Date: 2023-03

Variant appearance in text: KRAS: Y32S

PubMed Link: 37223497

Variant Present in the following documents:

• Main text

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The current state of the art and future trends in RAS-targeted cancer therapies.

Nature Reviews. Clinical Oncology

Punekar, Salman R SR; Velcheti, Vamsidhar V; Neel, Benjamin G BG; Wong, Kwok-Kin KK

Publication Date: 2022-10

Variant appearance in text: KRAS: Y32S

PubMed Link: 36028717

Variant Present in the following documents:

• Main text
• 41571_2022_Article_671.pdf

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: KRAS: Y32S

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

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Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association

Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H

Publication Date: 2020-07

Variant appearance in text: KRAS: Y32S

PubMed Link: 32107691

Variant Present in the following documents:

• 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12

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Allele-specific inhibitors inactivate mutant KRAS G12C by a trapping mechanism.

Science (New York, N.Y.)

Lito, Piro P; Solomon, Martha M; Li, Lian-Sheng LS; Hansen, Rasmus R; Rosen, Neal N

Publication Date: 2016-02-05

Variant appearance in text: KRAS: Y32S

PubMed Link: 26841430

Variant Present in the following documents:

• Main text

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