KRAS c.82T>C ;(p.F28L)

Variant ID: 12-25398237-A-G

NM_004985.3(KRAS):c.82T>C;(p.F28L)

This variant was identified in 13 publications

View GRCh38 version.




Publications:


Beyond Structural Bioinformatics for Genomics with Dynamics Characterization of an Expanded KRAS Mutational Landscape.

Biorxiv : The Preprint Server For Biology
Ratnasinghe, Brian D BD; Haque, Neshatul N; Wagenknecht, Jessica B JB; Jensen, Davin R DR; Esparza, Guadalupe V GV; Leverence, Elise N EN; De Assuncao, Thiago Milech TM; Mathison, Angela J AJ; Lomberk, Gwen G; Smith, Brian C BC; Volkman, Brian F BF; Urrutia, Raul R; Zimmermann, Michael T MT
Publication Date: 2023-04-28

Variant appearance in text: KRAS: F28L
PubMed Link: 37207265
Variant Present in the following documents:
  • Main text
  • nihpp-2023.04.28.536249v1.pdf
View BVdb publication page



A full-proteome, interaction-specific characterization of mutational hotspots across human cancers.

Genome Research
Chen, Siwei S; Liu, Yuan Y; Zhang, Yingying Y; Wierbowski, Shayne D SD; Lipkin, Steven M SM; Wei, Xiaomu X; Yu, Haiyuan H
Publication Date: 2022-01

Variant appearance in text: KRAS: F28L
PubMed Link: 34963661
Variant Present in the following documents:
  • supp_gr.275437.121_Supplementary_Table_1.xlsx, sheet 3
View BVdb publication page



Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology
Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C
Publication Date: 2021

Variant appearance in text: KRAS: F28L
PubMed Link: 34630336
Variant Present in the following documents:
  • Table_1.xlsx, sheet 2
View BVdb publication page



Whole-genome sequencing of recurrent neuroblastoma reveals somatic mutations that affect key players in cancer progression and telomere maintenance.

Scientific Reports
Fransson, Susanne S; Martinez-Monleon, Angela A; Johansson, Mathias M; Sjöberg, Rose-Marie RM; Björklund, Caroline C; Ljungman, Gustaf G; Ek, Torben T; Kogner, Per P; Martinsson, Tommy T
Publication Date: 2020-12-31

Variant appearance in text: KRAS: F28L
PubMed Link: 33384420
Variant Present in the following documents:
  • 41598_2020_Article_78370.pdf
View BVdb publication page



Clinical advantage of targeted sequencing for unbiased tumor mutational burden estimation in samples with low tumor purity.

Journal For Immunotherapy Of Cancer
Hong, Tae Hee TH; Cha, Hongui H; Shim, Joon Ho JH; Lee, Boram B; Chung, Jongsuk J; Lee, Chung C; Kim, Nayoung K D NKD; Choi, Yoon-La YL; Hwang, Soohyun S; Lee, Yoomi Y; Park, Sehhoon S; Jung, Hyun Ae HA; Kim, Ji-Yeon JY; Park, Yeon Hee YH; Sun, Jong-Mu JM; Ahn, Jin Seok JS; Ahn, Myung-Ju MJ; Park, Keunchil K; Lee, Se-Hoon SH; Park, Woong-Yang WY
Publication Date: 2020-10

Variant appearance in text: KRAS: F28L
PubMed Link: 33077514
Variant Present in the following documents:
  • jitc-2020-001199supp002.pdf
View BVdb publication page



Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association
Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H
Publication Date: 2020-07

Variant appearance in text: KRAS: F28L
PubMed Link: 32107691
Variant Present in the following documents:
  • 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12
View BVdb publication page



Comparative analysis of functional assay evidence use by ClinGen Variant Curation Expert Panels.

Genome Medicine
Kanavy, Dona M DM; McNulty, Shannon M SM; Jairath, Meera K MK; Brnich, Sarah E SE; Bizon, Chris C; Powell, Bradford C BC; Berg, Jonathan S JS
Publication Date: 2019-11-29

Variant appearance in text: KRAS: F28L
PubMed Link: 31783775
Variant Present in the following documents:
  • 13073_2019_683_MOESM2_ESM.xlsx, sheet 13
View BVdb publication page



From mutations to mechanisms and dysfunction via computation and mining of protein energy landscapes.

Bmc Genomics
Qiao, Wanli W; Akhter, Nasrin N; Fang, Xiaowen X; Maximova, Tatiana T; Plaku, Erion E; Shehu, Amarda A
Publication Date: 2018-09-24

Variant appearance in text: KRAS: F28L
PubMed Link: 30255791
Variant Present in the following documents:
  • 12864_2018_Article_5024.pdf
View BVdb publication page



Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Publication Date: 2018

Variant appearance in text: KRAS: F28L
PubMed Link: 29698444
Variant Present in the following documents:
  • pone.0196434.s001.xlsx, sheet 1
View BVdb publication page



Quantitative Systems Pharmacology Analysis of KRAS G12C Covalent Inhibitors.

Cpt: Pharmacometrics & Systems Pharmacology
Stites, Edward C EC; Shaw, Andrey S AS
Publication Date: 2018-05

Variant appearance in text: KRAS: F28L
PubMed Link: 29484842
Variant Present in the following documents:
  • Main text
  • PSP4-7-342.pdf
View BVdb publication page



KRAS Alleles: The Devil Is in the Detail.

Trends In Cancer
Haigis, Kevin M KM
Publication Date: 2017-10

Variant appearance in text: KRAS: F28L
PubMed Link: 28958387
Variant Present in the following documents:
  • Main text
View BVdb publication page



RASopathy Gene Mutations in Melanoma.

The Journal Of Investigative Dermatology
Halaban, Ruth R; Krauthammer, Michael M
Publication Date: 2016-09

Variant appearance in text: KRAS: F28L
PubMed Link: 27236105
Variant Present in the following documents:
  • Main text
View BVdb publication page



Germline KRAS mutations cause aberrant biochemical and physical properties leading to developmental disorders.

Human Mutation
Gremer, Lothar L; Merbitz-Zahradnik, Torsten T; Dvorsky, Radovan R; Cirstea, Ion C IC; Kratz, Christian Peter CP; Zenker, Martin M; Wittinghofer, Alfred A; Ahmadian, Mohammad Reza MR
Publication Date: 2011-01

Variant appearance in text: KRAS: F28L
PubMed Link: 20949621
Variant Present in the following documents:
  • Main text
View BVdb publication page