KRAS c.49_50delinsGA ;(p.S17D)

Variant ID: 12-25398269-CT-TC

NM_004985.3(KRAS):c.49_50delinsGA;(p.S17D)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


Elucidating the mechanism behind and investigating the efficacy of Traditional Chinese Medicine and Traditional Tibetan Medicine in combination with standard therapeutics in hepatocellular carcinoma and cholangiocarcinoma in vitro.

Frontiers In Pharmacology
Suo, Huizhen H; Hochnadel, Inga I; Petriv, Nataliia N; Franke, Raimo R; Schmidt, Jennifer J; Limanska, Nataliia N; Tugai, Alisa A; Jedicke, Nils N; Broenstrup, Mark M; Manns, Michael P MP; Yevsa, Tetyana T
Publication Date: 2022

Variant appearance in text: KRAS: S17D
PubMed Link: 36172191
Variant Present in the following documents:
  • Main text
View BVdb publication page



Comprehensive Genomic Profiling of Neuroendocrine Carcinomas of the Gastrointestinal System.

Cancer Discovery
Yachida, Shinichi S; Totoki, Yasushi Y; Noë, Michaël M; Nakatani, Yoichiro Y; Horie, Masafumi M; Kawasaki, Kenta K; Nakamura, Hiromi H; Saito-Adachi, Mihoko M; Suzuki, Masami M; Takai, Erina E; Hama, Natsuko N; Higuchi, Ryota R; Hirono, Seiko S; Shiba, Satoshi S; Kato, Mamoru M; Furukawa, Eisaku E; Arai, Yasuhito Y; Rokutan, Hirofumi H; Hashimoto, Taiki T; Mitsunaga, Shuichi S; Kanda, Mitsuro M; Tanaka, Hidenori H; Takata, So S; Shimomura, Ayaka A; Oshima, Minoru M; Hackeng, Wenzel M WM; Okumura, Tomoyuki T; Okano, Keiichi K; Yamamoto, Masakazu M; Yamaue, Hiroki H; Morizane, Chigusa C; Arihiro, Koji K; Furukawa, Toru T; Sato, Toshiro T; Kiyono, Tohru T; Brosens, Lodewijk A A LAA; Wood, Laura D LD; Hruban, Ralph H RH; Shibata, Tatsuhiro T
Publication Date: 2022-03-01

Variant appearance in text: KRAS: S17D
PubMed Link: 34880079
Variant Present in the following documents:
  • 692.pdf
View BVdb publication page



Failure to induce apoptosis via BCL-2 family proteins underlies lack of efficacy of combined MEK and PI3K inhibitors for KRAS-mutant lung cancers.

Cancer Research
Hata, Aaron N AN; Yeo, Alan A; Faber, Anthony C AC; Lifshits, Eugene E; Chen, Zhao Z; Cheng, Katherine A KA; Walton, Zandra Z; Sarosiek, Kristopher A KA; Letai, Anthony A; Heist, Rebecca S RS; Mino-Kenudson, Mari M; Wong, Kwok-Kin KK; Engelman, Jeffrey A JA
Publication Date: 2014-06-01

Variant appearance in text: KRAS: S17D
PubMed Link: 24675361
Variant Present in the following documents:
  • Main text
View BVdb publication page