KRAS c.39C>A ;(p.G13=)

Variant ID: 12-25398280-G-T

NM_004985.3(KRAS):c.39C>A;(p.G13=)

This variant was identified in 30 publications

View GRCh38 version.




Publications:


Network expansion of genetic associations defines a pleiotropy map of human cell biology.

Nature Genetics
Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P
Publication Date: 2023-02-23

Variant appearance in text: KRAS: 39C>A
PubMed Link: 36823319
Variant Present in the following documents:
  • 41588_2023_1327_MOESM4_ESM.xlsx, sheet 6
View BVdb publication page



Somatic mutation distribution across tumour cohorts provides a signal for positive selection in cancer.

Nature Communications
Boström, Martin M; Larsson, Erik E
Publication Date: 2022-11-17

Variant appearance in text: KRAS: G13G
PubMed Link: 36396655
Variant Present in the following documents:
  • 41467_2022_34746_MOESM10_ESM.xlsx, sheet 1
View BVdb publication page



Genomic landscape, immune characteristics and prognostic mutation signature of cervical cancer in China.

Bmc Medical Genomics
Liu, Jing J; Li, Zirong Z; Lu, Ting T; Pan, Junping J; Li, Li L; Song, Yanwen Y; Hu, Dan D; Zhuo, Yanhong Y; Chen, Ying Y; Xu, Qin Q
Publication Date: 2022-11-04

Variant appearance in text: KRAS: 39C>A
PubMed Link: 36333792
Variant Present in the following documents:
  • 12920_2022_1376_MOESM1_ESM.xlsx, sheet 1
View BVdb publication page



Genomic Landscape of RTK/RAS Pathway and Tumor Immune Infiltration as Prognostic Indicator of Lung Adenocarcinoma.

Frontiers In Oncology
Yin, Xiang-Qian XQ; Yin, Xue-Hui XH; Yu, Ya-Qin YQ; Xu, Lang L; Zhang, Mao M
Publication Date: 2022

Variant appearance in text: KRAS: 39C>A; G13G
PubMed Link: 35936718
Variant Present in the following documents:
  • Table_4.xlsx, sheet 2
View BVdb publication page



The Effect of the Kirsten Rat Sarcoma Viral Oncogene Homolog (Kras) Proto-Oncogene, GTPase Genetic Polymorphism on the Safety and Efficacy of Bevacizumab Combination Treatment Regimens for Patients with Nonsquamous, Non-Small Cell Lung Cancer with Brain Metastases.

Genetic Testing And Molecular Biomarkers
Song, Zizheng Z; Ren, Guanying G; Wang, Xiaolei X; Hu, Ling L
Publication Date: 2022-05

Variant appearance in text: rs397517040
PubMed Link: 35638910
Variant Present in the following documents:
  • Main text
  • gtmb.2021.0219.pdf
View BVdb publication page



Establishment of patient-derived organoids and a characterization-based drug discovery platform for treatment of pancreatic cancer.

Bmc Cancer
Watanabe, Sadanori S; Yogo, Akitada A; Otsubo, Tsuguteru T; Umehara, Hiroki H; Oishi, Jun J; Kodo, Toru T; Masui, Toshihiko T; Takaishi, Shigeo S; Seno, Hiroshi H; Uemoto, Shinji S; Hatano, Etsuro E
Publication Date: 2022-05-03

Variant appearance in text: rs397517040
PubMed Link: 35505283
Variant Present in the following documents:
  • 12885_2022_9619_MOESM1_ESM.xlsx, sheet 7
  • 12885_2022_9619_MOESM1_ESM.xlsx, sheet 8
  • 12885_2022_9619_MOESM1_ESM.xlsx, sheet 3
  • 12885_2022_9619_MOESM1_ESM.xlsx, sheet 9
  • 12885_2022_9619_MOESM1_ESM.xlsx, sheet 5
  • 12885_2022_9619_MOESM1_ESM.xlsx, sheet 4
View BVdb publication page



KLF3 and PAX6 are candidate driver genes in late-stage, MSI-hypermutated endometrioid endometrial carcinomas.

Plos One
Rudd, Meghan L ML; Hansen, Nancy F NF; Zhang, Xiaolu X; Urick, Mary Ellen ME; Zhang, Suiyuan S; Merino, Maria J MJ; , ; Mullikin, James C JC; Brody, Lawrence C LC; Bell, Daphne W DW
Publication Date: 2022

Variant appearance in text: rs397517040
PubMed Link: 35081118
Variant Present in the following documents:
  • pone.0251286.s005.xlsx, sheet 8
View BVdb publication page



KLF3 and PAX6 are candidate driver genes in late-stage, MSI-hypermutated endometrioid endometrial carcinomas.

Plos One
Rudd, Meghan L ML; Hansen, Nancy F NF; Zhang, Xiaolu X; Urick, Mary Ellen ME; Zhang, Suiyuan S; Merino, Maria J MJ; , ; Mullikin, James C JC; Brody, Lawrence C LC; Bell, Daphne W DW
Publication Date: 2022

Variant appearance in text: rs397517040
PubMed Link: 35081118
Variant Present in the following documents:
  • pone.0251286.s005.xlsx, sheet 8
View BVdb publication page



Oncogene Concatenated Enriched Amplicon Nanopore Sequencing for rapid, accurate, and affordable somatic mutation detection.

Genome Biology
Thirunavukarasu, Deepak D; Cheng, Lauren Y LY; Song, Ping P; Chen, Sherry X SX; Borad, Mitesh J MJ; Kwong, Lawrence L; James, Phillip P; Turner, Daniel J DJ; Zhang, David Yu DY
Publication Date: 2021-09-06

Variant appearance in text: rs397517040
PubMed Link: 34482832
Variant Present in the following documents:
  • 13059_2021_2449_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



Clinical Utility of Liquid Biopsy-Based Actionable Mutations Detected via ddPCR.

Biomedicines
Palacín-Aliana, Irina I; García-Romero, Noemí N; Asensi-Puig, Adrià A; Carrión-Navarro, Josefa J; González-Rumayor, Víctor V; Ayuso-Sacido, Ángel Á
Publication Date: 2021-07-28

Variant appearance in text: KRAS: G13G
PubMed Link: 34440110
Variant Present in the following documents:
  • Main text
  • biomedicines-09-00906.pdf
View BVdb publication page



Clinical Application of Next-Generation Sequencing of Plasma Cell-Free DNA for Genotyping Untreated Advanced Non-Small Cell Lung Cancer.

Cancers
Fernandes, Maria Gabriela O MGO; Cruz-Martins, Natália N; Souto Moura, Conceição C; Guimarães, Susana S; Pereira Reis, Joana J; Justino, Ana A; Pina, Maria João MJ; Magalhães, Adriana A; Queiroga, Henrique H; Machado, José Carlos JC; Hespanhol, Venceslau V; Costa, José Luis JL
Publication Date: 2021-05-30

Variant appearance in text: KRAS: G13G
PubMed Link: 34070940
Variant Present in the following documents:
  • Main text
  • cancers-13-02707.pdf
View BVdb publication page



Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Thoracic Cancer
Asselta, Rosanna R; Di Tommaso, Luca L; Perrino, Matteo M; Destro, Annarita A; Giordano, Laura L; Cardamone, Giulia G; Rubino, Luca L; Santoro, Armando A; Duga, Stefano S; Zucali, Paolo Andrea PA
Publication Date: 2021-05

Variant appearance in text: KRAS: 39C>A; G13G
PubMed Link: 33704917
Variant Present in the following documents:
  • TCA-12-1271-s003.xls, sheet 1
View BVdb publication page



Circulating Tumor DNA Detection by Digital-Droplet PCR in Pancreatic Ductal Adenocarcinoma: A Systematic Review.

Cancers
Huerta, Marisol M; Roselló, Susana S; Sabater, Luis L; Ferrer, Ana A; Tarazona, Noelia N; Roda, Desamparados D; Gambardella, Valentina V; Alfaro-Cervelló, Clara C; Garcés-Albir, Marina M; Cervantes, Andrés A; Ibarrola-Villava, Maider M
Publication Date: 2021-02-27

Variant appearance in text: KRAS: G13G
PubMed Link: 33673558
Variant Present in the following documents:
  • Main text
  • cancers-13-00994.pdf
View BVdb publication page



Usefulness of a novel device to divide core needle biopsy specimens in a spatially matched fashion.

Scientific Reports
Shiraishi, Takumi T; Inui, Shogo S; Inoue, Yuta Y; Saito, Yumiko Y; Taga, Hideto H; Kaneko, Masatomo M; Tsuji, Keisuke K; Ueda, Saya S; Ueda, Takashi T; Matsugasumi, Toru T; Taniguchi, Hidefumi H; Ueno, Akihisa A; Yamada, Takeshi T; Yamada, Yasuhiro Y; Iwata, Tsuyoshi T; Fujihara, Atsuko A; Hongo, Fumiya F; Ukimura, Osamu O
Publication Date: 2020-10-13

Variant appearance in text: rs397517040
PubMed Link: 33051506
Variant Present in the following documents:
  • 41598_2020_74136_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



The Clinical Significance of RAS, PIK3CA, and PTEN Mutations in Non-Small Cell Lung Cancer Using Cell-Free DNA.

Journal Of Clinical Medicine
Chang, Won Jin WJ; Sung, Jae Sook JS; Lee, Sung Yong SY; Kang, Eun Joo EJ; Kwon, Nak-Jung NJ; Kim, Hae Mi HM; Shin, Sang Won SW; Choi, Jung Yoon JY; Choi, Yoon Ji YJ; Kim, Ju Won JW; Park, Kyong Hwa KH; Kim, Yeul Hong YH
Publication Date: 2020-08-14

Variant appearance in text: KRAS: G13G
PubMed Link: 32823871
Variant Present in the following documents:
  • Main text
  • jcm-09-02642-s001.pdf
  • jcm-09-02642.pdf
View BVdb publication page



Landscape of somatic single nucleotide variants and indels in colorectal cancer and impact on survival.

Nature Communications
Zaidi, Syed H SH; Harrison, Tabitha A TA; Phipps, Amanda I AI; Steinfelder, Robert R; Trinh, Quang M QM; Qu, Conghui C; Banbury, Barbara L BL; Georgeson, Peter P; Grasso, Catherine S CS; Giannakis, Marios M; Adams, Jeremy B JB; Alwers, Elizabeth E; Amitay, Efrat L EL; Barfield, Richard T RT; Berndt, Sonja I SI; Borozan, Ivan I; Brenner, Hermann H; Brezina, Stefanie S; Buchanan, Daniel D DD; Cao, Yin Y; Chan, Andrew T AT; Chang-Claude, Jenny J; Connolly, Charles M CM; Drew, David A DA; Farris, Alton Brad AB; Figueiredo, Jane C JC; French, Amy J AJ; Fuchs, Charles S CS; Garraway, Levi A LA; Gruber, Steve S; Guinter, Mark A MA; Hamilton, Stanley R SR; Harlid, Sophia S; Heisler, Lawrence E LE; Hidaka, Akihisa A; Hopper, John L JL; Huang, Wen-Yi WY; Huyghe, Jeroen R JR; Jenkins, Mark A MA; Krzyzanowski, Paul M PM; Lemire, Mathieu M; Lin, Yi Y; Luo, Xuemei X; Mardis, Elaine R ER; McPherson, John D JD; Miller, Jessica K JK; Moreno, Victor V; Mu, Xinmeng Jasmine XJ; Nishihara, Reiko R; Papadopoulos, Nickolas N; Pasternack, Danielle D; Quist, Michael J MJ; Rafikova, Adilya A; Reid, Emma E G EEG; Shinbrot, Eve E; Shirts, Brian H BH; Stein, Lincoln D LD; Teney, Cherie D CD; Timms, Lee L; Um, Caroline Y CY; Van Guelpen, Bethany B; Van Tassel, Megan M; Wang, Xiaolong X; Wheeler, David A DA; Yung, Christina K CK; Hsu, Li L; Ogino, Shuji S; Gsur, Andrea A; Newcomb, Polly A PA; Gallinger, Steven S; Hoffmeister, Michael M; Campbell, Peter T PT; Thibodeau, Stephen N SN; Sun, Wei W; Hudson, Thomas J TJ; Peters, Ulrike U
Publication Date: 2020-07-20

Variant appearance in text: KRAS: G13G
PubMed Link: 32686686
Variant Present in the following documents:
  • 41467_2020_17386_MOESM4_ESM.xlsx, sheet 1
View BVdb publication page



mTOR Signaling and SREBP Activity Increase FADS2 Expression and Can Activate Sapienate Biosynthesis.

Cell Reports
Triki, Mouna M; Rinaldi, Gianmarco G; Planque, Melanie M; Broekaert, Dorien D; Winkelkotte, Alina M AM; Maier, Carina R CR; Janaki Raman, Sudha S; Vandekeere, Anke A; Van Elsen, Joke J; Orth, Martin F MF; Grünewald, Thomas G P TGP; Schulze, Almut A; Fendt, Sarah-Maria SM
Publication Date: 2020-06-23

Variant appearance in text: KRAS: G13G
PubMed Link: 32579932
Variant Present in the following documents:
  • mmc5.xlsx, sheet 3
View BVdb publication page



Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D.

Nature Communications
Kennedy, Susan A SA; Jarboui, Mohamed-Ali MA; Srihari, Sriganesh S; Raso, Cinzia C; Bryan, Kenneth K; Dernayka, Layal L; Charitou, Theodosia T; Bernal-Llinares, Manuel M; Herrera-Montavez, Carlos C; Krstic, Aleksandar A; Matallanas, David D; Kotlyar, Max M; Jurisica, Igor I; Curak, Jasna J; Wong, Victoria V; Stagljar, Igor I; LeBihan, Thierry T; Imrie, Lisa L; Pillai, Priyanka P; Lynn, Miriam A MA; Fasterius, Erik E; Al-Khalili Szigyarto, Cristina C; Breen, James J; Kiel, Christina C; Serrano, Luis L; Rauch, Nora N; Rukhlenko, Oleksii O; Kholodenko, Boris N BN; Iglesias-Martinez, Luis F LF; Ryan, Colm J CJ; Pilkington, Ruth R; Cammareri, Patrizia P; Sansom, Owen O; Shave, Steven S; Auer, Manfred M; Horn, Nicola N; Klose, Franziska F; Ueffing, Marius M; Boldt, Karsten K; Lynn, David J DJ; Kolch, Walter W
Publication Date: 2020-01-24

Variant appearance in text: KRAS: G13G
PubMed Link: 31980649
Variant Present in the following documents:
  • 41467_2019_14224_MOESM1_ESM.pdf
View BVdb publication page



A pan-cancer analysis of synonymous mutations.

Nature Communications
Sharma, Yogita Y; Miladi, Milad M; Dukare, Sandeep S; Boulay, Karine K; Caudron-Herger, Maiwen M; Groß, Matthias M; Backofen, Rolf R; Diederichs, Sven S
Publication Date: 2019-06-12

Variant appearance in text: KRAS: G13G
PubMed Link: 31189880
Variant Present in the following documents:
  • Main text
  • 41467_2019_Article_10489.pdf
View BVdb publication page



An integrated genomic analysis of anaplastic meningioma identifies prognostic molecular signatures.

Scientific Reports
Collord, Grace G; Tarpey, Patrick P; Kurbatova, Natalja N; Martincorena, Inigo I; Moran, Sebastian S; Castro, Manuel M; Nagy, Tibor T; Bignell, Graham G; Maura, Francesco F; Young, Matthew D MD; Berna, Jorge J; Tubio, Jose M C JMC; McMurran, Chris E CE; Young, Adam M H AMH; Sanders, Mathijs M; Noorani, Imran I; Price, Stephen J SJ; Watts, Colin C; Leipnitz, Elke E; Kirsch, Matthias M; Schackert, Gabriele G; Pearson, Danita D; Devadass, Abel A; Ram, Zvi Z; Collins, V Peter VP; Allinson, Kieren K; Jenkinson, Michael D MD; Zakaria, Rasheed R; Syed, Khaja K; Hanemann, C Oliver CO; Dunn, Jemma J; McDermott, Michael W MW; Kirollos, Ramez W RW; Vassiliou, George S GS; Esteller, Manel M; Behjati, Sam S; Brazma, Alvis A; Santarius, Thomas T; McDermott, Ultan U
Publication Date: 2018-09-10

Variant appearance in text: KRAS: G13G
PubMed Link: 30202034
Variant Present in the following documents:
  • 41598_2018_31659_MOESM2_ESM.xlsx, sheet 30
View BVdb publication page



The landscape of somatic mutation in sporadic Chinese colorectal cancer.

Oncotarget
Liu, Zhe Z; Yang, Chao C; Li, Xiangchun X; Luo, Wen W; Roy, Bhaskar B; Xiong, Teng T; Zhang, Xiuqing X; Yang, Huanming H; Wang, Jian J; Ye, Zhenhao Z; Chen, Yang Y; Song, Jinghe J; Ma, Shuai S; Zhou, Yong Y; Yang, Min M; Fang, Xiaodong X; Du, Jie J
Publication Date: 2018-06-08

Variant appearance in text: rs397517040
PubMed Link: 29937994
Variant Present in the following documents:
  • oncotarget-09-27412-s005.xlsx, sheet 1
View BVdb publication page



Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Publication Date: 2018

Variant appearance in text: KRAS: G13G
PubMed Link: 29698444
Variant Present in the following documents:
  • pone.0196434.s001.xlsx, sheet 3
  • pone.0196434.s001.xlsx, sheet 1
  • pone.0196434.s001.xlsx, sheet 2
View BVdb publication page



DNA terminal structure-mediated enzymatic reaction for ultra-sensitive discrimination of single nucleotide variations in circulating cell-free DNA.

Nucleic Acids Research
Wu, Tongbo T; Chen, Wei W; Yang, Ziyu Z; Tan, Haocheng H; Wang, Jiayu J; Xiao, Xianjin X; Li, Mengyuan M; Zhao, Meiping M
Publication Date: 2018-02-28

Variant appearance in text: KRAS: G13G
PubMed Link: 29190359
Variant Present in the following documents:
  • gkx1218_supp.pdf
View BVdb publication page



Pan-urologic cancer genomic subtypes that transcend tissue of origin.

Nature Communications
Chen, Fengju F; Zhang, Yiqun Y; Bossé, Dominick D; Lalani, Aly-Khan A AA; Hakimi, A Ari AA; Hsieh, James J JJ; Choueiri, Toni K TK; Gibbons, Don L DL; Ittmann, Michael M; Creighton, Chad J CJ
Publication Date: 2017-08-04

Variant appearance in text: KRAS: 39C>A
PubMed Link: 28775315
Variant Present in the following documents:
  • 41467_2017_289_MOESM7_ESM.xlsx, sheet 1
View BVdb publication page



Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Nature Communications
Kis, Olena O; Kaedbey, Rayan R; Chow, Signy S; Danesh, Arnavaz A; Dowar, Mark M; Li, Tiantian T; Li, Zhihua Z; Liu, Jessica J; Mansour, Mark M; Masih-Khan, Esther E; Zhang, Tong T; Bratman, Scott V SV; Oza, Amit M AM; Kamel-Reid, Suzanne S; Trudel, Suzanne S; Pugh, Trevor J TJ
Publication Date: 2017-05-11

Variant appearance in text: KRAS: G13G; rs397517040
PubMed Link: 28492226
Variant Present in the following documents:
  • ncomms15086-s3.xlsx, sheet 1
View BVdb publication page



VarDict: a novel and versatile variant caller for next-generation sequencing in cancer research.

Nucleic Acids Research
Lai, Zhongwu Z; Markovets, Aleksandra A; Ahdesmaki, Miika M; Chapman, Brad B; Hofmann, Oliver O; McEwen, Robert R; Johnson, Justin J; Dougherty, Brian B; Barrett, J Carl JC; Dry, Jonathan R JR
Publication Date: 2016-06-20

Variant appearance in text: KRAS: 39C>A
PubMed Link: 27060149
Variant Present in the following documents:
  • supp_gkw227_nar-03544-met-k-2015-File003.xls, sheet 2
View BVdb publication page



KRAS and BRAF gene mutations and DNA mismatch repair status in Chinese colorectal carcinoma patients.

World Journal Of Gastroenterology
Ye, Ju-Xiang JX; Liu, Yan Y; Qin, Yun Y; Zhong, Hao-Hao HH; Yi, Wei-Ning WN; Shi, Xue-Ying XY
Publication Date: 2015-02-07

Variant appearance in text: KRAS: G13G
PubMed Link: 25663779
Variant Present in the following documents:
  • Main text
View BVdb publication page



The role of kras mutations and MSI status in diagnosis of colorectal cancer.

Gastroenterology And Hepatology From Bed To Bench
Shemirani, Atena Irani AI; Haghighi, Mahdi Montazer MM; Milanizadeh, Saman S; Taleghani, Mohammad Yaghoob MY; Fatemi, Seyed Reza SR; Damavand, Behzad B; Akbari, Zahra Z; Zali, Mohammad Reza MR
Publication Date: 2011

Variant appearance in text: KRAS: Gly13Gly
PubMed Link: 24834160
Variant Present in the following documents:
  • GHFBB-4-070.pdf
View BVdb publication page



Comprehensive mutation analysis in colorectal flat adenomas.

Plos One
Voorham, Quirinus J M QJ; Carvalho, Beatriz B; Spiertz, Angela J AJ; Claes, Bart B; Mongera, Sandra S; van Grieken, Nicole C T NC; Grabsch, Heike H; Kliment, Martin M; Rembacken, Bjorn B; van de Wiel, Mark A MA; Quirke, Philip P; Mulder, Chris J J CJ; Lambrechts, Diether D; van Engeland, Manon M; Meijer, Gerrit A GA
Publication Date: 2012

Variant appearance in text: KRAS: 39C>A
PubMed Link: 22848674
Variant Present in the following documents:
  • Main text
View BVdb publication page



KRAS, BRAF and PIK3CA mutations and the loss of PTEN expression in Chinese patients with colorectal cancer.

Plos One
Mao, Chen C; Zhou, Junhua J; Yang, Zuyao Z; Huang, Yafang Y; Wu, Xinyin X; Shen, Hong H; Tang, Jinling J; Chen, Qing Q
Publication Date: 2012

Variant appearance in text: KRAS: G13G
PubMed Link: 22586484
Variant Present in the following documents:
  • Main text
  • pone.0036653.pdf
View BVdb publication page



SNaPshot and StripAssay as valuable alternatives to direct sequencing for KRAS mutation detection in colon cancer routine diagnostics.

The Journal Of Molecular Diagnostics : Jmd
Fariña Sarasqueta, Arantza A; Moerland, Elna E; de Bruyne, Hanneke H; de Graaf, Henk H; Vrancken, Tamara T; van Lijnschoten, Gesina G; van den Brule, Adriaan J C AJ
Publication Date: 2011-03

Variant appearance in text: KRAS: 39C>A
PubMed Link: 21354055
Variant Present in the following documents:
  • Main text
View BVdb publication page